2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Abnormalities, Autosome in 6 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mimmler, M | 1 |
| Peter, S | 1 |
| Kraus, A | 1 |
| Stroh, S | 1 |
| Nikolova, T | 1 |
| Seiwert, N | 1 |
| Hasselwander, S | 1 |
| Neitzel, C | 1 |
| Haub, J | 1 |
| Monien, BH | 1 |
| Nicken, P | 1 |
| Steinberg, P | 1 |
| Shay, JW | 1 |
| Kaina, B | 1 |
| Fahrer, J | 1 |
| Christian, AT | 1 |
| Snyderwine, EG | 1 |
| Tucker, JD | 3 |
| El-Zein, R | 1 |
| Etzel, CJ | 1 |
| Lopez, MS | 1 |
| Gu, Y | 1 |
| Spitz, MR | 1 |
| Strom, SS | 1 |
| Director, AE | 1 |
| Nath, J | 1 |
| Ramsey, MJ | 1 |
| Swiger, RR | 1 |
| Otsuka, C | 1 |
| Miura, KF | 1 |
| Satoh, T | 1 |
| Hatanaka, M | 1 |
| Wakabayashi, K | 1 |
| Ishidate, M | 1 |
| Buonarati, MH | 1 |
| Minkler, JL | 1 |
| Wu, RW | 1 |
| Thompson, LH | 1 |
| Felton, JS | 1 |
6 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Abnormalities, Autosome
| Article | Year |
|---|---|
DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Carcinogens; Cattle; Cell Line; Cell Survival; Chec | 2016 |
Comparative genomic hybridization analysis of PhIP-induced mammary carcinomas in rats reveals a cytogenetic signature.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chromosome Aberrations; Chromosomes; DNA, Ne | 2002 |
Human sensitivity to PhIP: a novel marker for prostate cancer risk.
Topics: Adult; Aged; Case-Control Studies; Cells, Cultured; Chromosome Aberrations; Chromosome Breakage; Dos | 2006 |
Cytogenetic analysis of mice chronically fed the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine.
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Diet; Dose-Response Relationship, Drug; Female; Fo | 1996 |
Cytogenetic effects of a food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-beta]pyridine (PhIP), and its metabolite, 2-hydroxyamino-1-methy-6-phenylimidazo[4,5-beta]pyridine (N-OH-PhIP), on human and Chinese hamster cells in vitro.
Topics: Adult; Animals; Biotransformation; Cells, Cultured; CHO Cells; Chromosome Aberrations; Cricetinae; F | 1996 |
Metabolic activation and cytogenetic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in Chinese hamster ovary cells expressing murine cytochrome P450 IA2.
Topics: Animals; Biotransformation; Cell Line; Chromosome Aberrations; Cytochrome P-450 CYP1A2; Cytochrome P | 1991 |