2-acetylaminofluorene has been researched along with Urinary Calculi in 1 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Urinary Calculi: Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In contrast, nongenotoxic chemicals, such as chemicals causing urinary calculi or sodium saccharin and related sodium and potassium salts, frequently are carcinogenic only at high doses and/or only in specific species." | 4.79 | Human relevance of animal carcinogenicity studies. ( Cohen, SM, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, SM | 1 |
1 review available for 2-acetylaminofluorene and Urinary Calculi
| Article | Year |
|---|---|
Human relevance of animal carcinogenicity studies.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenicity Tests; Cocarcinogenesis; Disease Models, Animal; FAN | 1995 |