2-acetylaminofluorene has been researched along with Rodent Diseases in 3 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Rodent Diseases: Diseases of rodents of the order RODENTIA. This term includes diseases of Sciuridae (squirrels), Geomyidae (gophers), Heteromyidae (pouched mice), Castoridae (beavers), Cricetidae (rats and mice), Muridae (Old World rats and mice), Erethizontidae (porcupines), and Caviidae (guinea pigs).
Excerpt | Relevance | Reference |
---|---|---|
"Data for nine different types of tumors from the large ED01 study conducted at the National Center for Toxicological Research were used to compare tumor prevalence rates among litters with the tumor rates expected under the assumption of homogeneity of tumor rates among litters." | 1.27 | Occurrence of tumors among litters of BALB/c female mice. ( Chen, JJ; Gaylor, DW; Greenman, DL; Thompson, CH, 1985) |
"Osteosarcomas were found in 16 of 24,192 (0." | 1.26 | Osteosarcomas in BALB/c female mice. ( Frith, CH; Highman, B; Johnson, BP, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (66.67) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Frith, CH | 1 |
Johnson, BP | 1 |
Highman, B | 1 |
Yoon, BI | 1 |
Jung, SY | 1 |
Hur, K | 1 |
Lee, JH | 1 |
Joo, KH | 1 |
Lee, YS | 1 |
Kim, DY | 1 |
Gaylor, DW | 1 |
Chen, JJ | 1 |
Greenman, DL | 1 |
Thompson, CH | 1 |
3 other studies available for 2-acetylaminofluorene and Rodent Diseases
Article | Year |
---|---|
Osteosarcomas in BALB/c female mice.
Topics: 2-Acetylaminofluorene; Animals; Bone Neoplasms; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; O | 1982 |
Differentiation of hamster liver oval cell following Clonorchis sinensis infection.
Topics: 2-Acetylaminofluorene; Albumins; Alkylating Agents; alpha-Fetoproteins; Animals; Carcinogens; Clonor | 2000 |
Occurrence of tumors among litters of BALB/c female mice.
Topics: 2-Acetylaminofluorene; Age Factors; Animals; Female; Litter Size; Liver Neoplasms; Mice; Mice, Inbre | 1985 |