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2-acetylaminofluorene and Rodent Diseases

2-acetylaminofluorene has been researched along with Rodent Diseases in 3 studies

2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

Rodent Diseases: Diseases of rodents of the order RODENTIA. This term includes diseases of Sciuridae (squirrels), Geomyidae (gophers), Heteromyidae (pouched mice), Castoridae (beavers), Cricetidae (rats and mice), Muridae (Old World rats and mice), Erethizontidae (porcupines), and Caviidae (guinea pigs).

Research Excerpts

ExcerptRelevanceReference
"Data for nine different types of tumors from the large ED01 study conducted at the National Center for Toxicological Research were used to compare tumor prevalence rates among litters with the tumor rates expected under the assumption of homogeneity of tumor rates among litters."1.27Occurrence of tumors among litters of BALB/c female mice. ( Chen, JJ; Gaylor, DW; Greenman, DL; Thompson, CH, 1985)
"Osteosarcomas were found in 16 of 24,192 (0."1.26Osteosarcomas in BALB/c female mice. ( Frith, CH; Highman, B; Johnson, BP, 1982)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frith, CH1
Johnson, BP1
Highman, B1
Yoon, BI1
Jung, SY1
Hur, K1
Lee, JH1
Joo, KH1
Lee, YS1
Kim, DY1
Gaylor, DW1
Chen, JJ1
Greenman, DL1
Thompson, CH1

Other Studies

3 other studies available for 2-acetylaminofluorene and Rodent Diseases

ArticleYear
Osteosarcomas in BALB/c female mice.
    Laboratory animal science, 1982, Volume: 32, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Bone Neoplasms; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; O

1982
Differentiation of hamster liver oval cell following Clonorchis sinensis infection.
    The Journal of veterinary medical science, 2000, Volume: 62, Issue:12

    Topics: 2-Acetylaminofluorene; Albumins; Alkylating Agents; alpha-Fetoproteins; Animals; Carcinogens; Clonor

2000
Occurrence of tumors among litters of BALB/c female mice.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:4

    Topics: 2-Acetylaminofluorene; Age Factors; Animals; Female; Litter Size; Liver Neoplasms; Mice; Mice, Inbre

1985