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2-acetylaminofluorene and Papilloma

2-acetylaminofluorene has been researched along with Papilloma in 7 studies

2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
" Hence, the levels of statistical significance obtained for dose-response trends and comparisons of treated and control groups were similar using 48 animals per dose groups with B6C3 mice, or combinations of 24 animals per dose from 2 genotypes, or 12 animals per dose from the 4 hybrid genotypes."1.28Bladder and liver tumorigenesis induced by 2-acetylaminofluorene in different F1 mouse hybrids: variation within genotypes and effects of using more than one genotype on risk assessment. ( Blackwell, BN; Gaylor, DW; Moore, GE; Wolff, GL, 1991)
"Bladder cancer was also present in rats administered the sequence of FANFT, 2-FAA, and 3,3'-DCB."1.26Summation effect of N-butyl-n-(4-hydroxybutyl)nitrosamine, N-(4-(5-nitro-2-furyl)-2-thiazoly)formamide, N-2-fluoroenylacetamide, and 3,3'-dichlorobenzidine on urinary bladder carcinogenesis in rats. ( Hananouchi, M; Hirose, M; Miyata, Y; Mizutani, M; Tatematsu, M, 1977)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MILLER, EC1
MILLER, JA1
ENOMOTO, M1
Williams, GM1
Maeura, Y1
Weisburger, JH1
Chen, JJ1
Anichkov, NM1
Tatematsu, M1
Miyata, Y1
Mizutani, M1
Hananouchi, M1
Hirose, M1
Matsumoto, M1
Hopp, ML1
Oyasu, R1
Wolff, GL1
Gaylor, DW1
Blackwell, BN1
Moore, GE1

Reviews

1 review available for 2-acetylaminofluorene and Papilloma

ArticleYear
[Experimental replication of bladder tumors. Morphologic features of early stages of their development].
    Vestnik Akademii meditsinskikh nauk SSSR, 1979, Issue:9

    Topics: 2-Acetylaminofluorene; 2-Naphthylamine; Animals; Butylhydroxybutylnitrosamine; Cell Membrane; Cell T

1979

Other Studies

6 other studies available for 2-acetylaminofluorene and Papilloma

ArticleYear
THE COMPARATIVE CARCINOGENICITIES OF 2-ACETYLAMINOFLUORENE AND ITS N-HYDROXY METABOLITE IN MICE, HAMSTERS, AND GUINEA PIGS.
    Cancer research, 1964, Volume: 24

    Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cricetinae; Croton Oil; Fluorenes; Guinea Pigs; Injecti

1964
Simultaneous inhibition of liver carcinogenicity and enhancement of bladder carcinogenicity of N-2-fluorenylacetamide by butylated hydroxytoluene.
    Cancer letters, 1983, Volume: 19, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Butylated Hydroxytoluene; Carcinoma; Carcinoma, Hepatocellular; Coca

1983
Global tests for analysis of multiple tumour data from animal carcinogenicity experiments.
    Statistics in medicine, 1996, Jun-15, Volume: 15, Issue:11

    Topics: 2-Acetylaminofluorene; Adenoma; Animals; Biological Assay; Carcinogenicity Tests; Carcinogens; Carci

1996
Summation effect of N-butyl-n-(4-hydroxybutyl)nitrosamine, N-(4-(5-nitro-2-furyl)-2-thiazoly)formamide, N-2-fluoroenylacetamide, and 3,3'-dichlorobenzidine on urinary bladder carcinogenesis in rats.
    Gan, 1977, Volume: 68, Issue:2

    Topics: 2-Acetylaminofluorene; 3,3'-Dichlorobenzidine; Animals; Benzidines; Biliary Tract Diseases; Butylhyd

1977
Effect of pair-feeding of carcinogen on the incidence of bladder tumors in hamsters. Role of indole, age, and sex.
    Investigative urology, 1976, Volume: 14, Issue:3

    Topics: 2-Acetylaminofluorene; Administration, Oral; Age Factors; Animals; Carcinoma; Cricetinae; Diet; Fema

1976
Bladder and liver tumorigenesis induced by 2-acetylaminofluorene in different F1 mouse hybrids: variation within genotypes and effects of using more than one genotype on risk assessment.
    Journal of toxicology and environmental health, 1991, Volume: 33, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Carcinoma; Female; Genotype; Liver Neoplasms, Experimental; Male; Mi

1991