2-acetylaminofluorene has been researched along with Osteosarcoma in 2 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Other malignant neoplasms, including leiomyosarcomas, granulosa cells tumors, adrenocortical carcinomas, angiosarcomas, squamous cell carcinomas, and harderian gland tumors, metastasized at an incidence of less than 5%." | 1.26 | Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide. ( Frith, CH; Littlefield, NA; Umholtz, R, 1981) |
| "Osteosarcomas were found in 16 of 24,192 (0." | 1.26 | Osteosarcomas in BALB/c female mice. ( Frith, CH; Highman, B; Johnson, BP, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frith, CH | 2 |
| Littlefield, NA | 1 |
| Umholtz, R | 1 |
| Johnson, BP | 1 |
| Highman, B | 1 |
2 other studies available for 2-acetylaminofluorene and Osteosarcoma
| Article | Year |
|---|---|
Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Adenocarcinoma; Animals; Carcinogens; Female; Fibrosarcoma; Kidney Neoplasms; | 1981 |
Osteosarcomas in BALB/c female mice.
Topics: 2-Acetylaminofluorene; Animals; Bone Neoplasms; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; O | 1982 |