2-acetylaminofluorene has been researched along with Obesity in 1 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Groups of 28 week old DIO and LEAN mice were dosed with the bioactivation-dependent DNA-reactive hepatocarcinogen 2-acetylaminofluorene (AAF), at 2." | 1.39 | Hepatocellular proliferation and hepatocarcinogen bioactivation in mice with diet-induced fatty liver and obesity. ( Duan, JD; Hayes, AN; Iatropoulos, MJ; Jeffrey, AM; Leach, MW; Stedman, NL; Williams, GM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iatropoulos, MJ | 1 |
| Duan, JD | 1 |
| Jeffrey, AM | 1 |
| Leach, MW | 1 |
| Hayes, AN | 1 |
| Stedman, NL | 1 |
| Williams, GM | 1 |
1 other study available for 2-acetylaminofluorene and Obesity
| Article | Year |
|---|---|
Hepatocellular proliferation and hepatocarcinogen bioactivation in mice with diet-induced fatty liver and obesity.
Topics: 2-Acetylaminofluorene; Animal Feed; Animals; Carcinogens; Cell Proliferation; Diet, Fat-Restricted; | 2013 |