2-acetylaminofluorene has been researched along with Neoplasms in 78 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aromatic amine 2-acetylaminofluorene (AAF) produced neoplasms in diverse target organs of many animal species." | 4.79 | 2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation. ( Verna, L; Whysner, J; Williams, GM, 1996) |
| "Susceptibility to cancer is determined at different levels such as the genetic polymorphism of enzymes involved in the activation and detoxification of carcinogens, the polymorphism of genes that maintains the genome stability, like those involved in DNA repair or recombination processes, and finally the polymorphism in oncogenes or tumour suppressor genes." | 2.41 | The early detection of frameshift mutations induced by a food-borne carcinogen in rats: a new tool for molecular epidemiology. ( Burnouf, DY; Fuchs, RP, 2000) |
| "Mouse models that mimic the human skin cancer-prone disease xeroderma pigmentosum (XP) provide an useful experimental system with which to study the relationship between the DNA repair process of nucleotide excision repair (NER) and ultraviolet- (UV) induced skin carcinogenesis." | 2.41 | Cancer predisposition in mutant mice defective in multiple genetic pathways: uncovering important genetic interactions. ( Burns, DK; Cheo, DL; Friedberg, EC; Meira, LB; Nahari, D; Reis, AM, 2001) |
| "To develop DR-HepG2, hepatocellular carcinoma cell line (HepG2) was transfected with 2-Acetylaminofluorene (AAF) and Aflatoxin B1 (AFB)." | 1.39 | Evaluation of hydro-alcoholic extract of Eclipta alba for its multidrug resistance reversal potential: an in vitro study. ( Chaudhary, H; Jena, PK; Seshadri, S, 2013) |
| "Comparisons on a linear and the Rozman logarithmic scale for dosage versus carcinogenicity in rodents are presented for methyl eugenol (ME), nitrosodiethylamine (NDEA), ethyl carbamate (EC) and 2-acetylaminofluorene (AAF)." | 1.33 | Comparisons of thresholds for carcinogenicity on linear and logarithmic dosage scales. ( Waddell, WJ, 2005) |
| " This is commonly thought of as a dose-response relationship which is linear at low dose." | 1.29 | Thresholds in chemical carcinogenesis. ( Auton, TR; Purchase, IF, 1995) |
| "Data for nine different types of tumors from the large ED01 study conducted at the National Center for Toxicological Research were used to compare tumor prevalence rates among litters with the tumor rates expected under the assumption of homogeneity of tumor rates among litters." | 1.27 | Occurrence of tumors among litters of BALB/c female mice. ( Chen, JJ; Gaylor, DW; Greenman, DL; Thompson, CH, 1985) |
| " A number of mathematical dose-response models have been proposed for extrapolation purposes; we have shown how similar they can appear to one another in the range of observable response rates, yet how different they become at lower, unobservable response rates, the region of primary interest." | 1.27 | Statistical aspects of the estimation of human risks. ( Brown, CC, 1985) |
| "Other malignant neoplasms, including leiomyosarcomas, granulosa cells tumors, adrenocortical carcinomas, angiosarcomas, squamous cell carcinomas, and harderian gland tumors, metastasized at an incidence of less than 5%." | 1.26 | Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide. ( Frith, CH; Littlefield, NA; Umholtz, R, 1981) |
| "These neoplasms included cholangiomas, hepatoadenomas, cholangiocarcinomas, and hepatocellular cancers." | 1.25 | Tumor induction by carcinogenic agents in aquarium fish. ( Khudoley, VV; Pliss, GB, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 64 (82.05) | 18.7374 |
| 1990's | 5 (6.41) | 18.2507 |
| 2000's | 6 (7.69) | 29.6817 |
| 2010's | 3 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wacher, VJ | 1 |
| Wu, CY | 1 |
| Benet, LZ | 1 |
| Chaudhary, H | 1 |
| Jena, PK | 1 |
| Seshadri, S | 1 |
| FOULDS, L | 2 |
| ORR, JW | 1 |
| BIELSCHOWSKY, F | 3 |
| HOCH-LIGETI, C | 2 |
| HARRIS, PN | 1 |
| DUNNING, WF | 2 |
| CURTIS, MR | 2 |
| MADSEN, ME | 1 |
| HEIMAN, J | 1 |
| MEISEL, D | 1 |
| Chen, CM | 1 |
| Lu, TF | 1 |
| Chen, MH | 1 |
| Hsu, CM | 1 |
| ENGEL, RW | 3 |
| COPELAND, DH | 3 |
| MORRIS, HP | 5 |
| EYESTONE, WH | 1 |
| LAIRD, AK | 1 |
| MILLER, EC | 4 |
| RUTMAN, RJ | 1 |
| CANTAROW, A | 2 |
| PASCHKIS, KE | 2 |
| MIYAJI, T | 1 |
| MOSZKOWSKI, LI | 1 |
| SENOO, T | 1 |
| OGATA, M | 1 |
| ODA, T | 1 |
| KAWAI, K | 1 |
| SAYAMA, Y | 1 |
| ISHIDA, H | 1 |
| MATSUO, H | 1 |
| MORI, K | 1 |
| ICHII, S | 2 |
| NAGASE, K | 1 |
| WAGNER, BP | 2 |
| VELAT, CA | 1 |
| MAISIN, J | 1 |
| LAMBERT, G | 1 |
| DECKERS-PASSAU, L | 1 |
| MALDAGUE, P | 1 |
| DAY, ED | 1 |
| PLANINSEK, JA | 1 |
| PRESSMAN, D | 1 |
| PERRY, DJ | 1 |
| RAY, FE | 1 |
| SNELL, KC | 1 |
| STEWART, HL | 1 |
| BENSON, WR | 1 |
| SIDRANSKY, H | 1 |
| CLARK, S | 1 |
| BABA, T | 1 |
| DYER, HM | 2 |
| KELLY, MG | 1 |
| IRVING, C | 1 |
| WEISBURGER, JH | 1 |
| WEISBURGER, EK | 2 |
| JABARA, AG | 1 |
| MELICOW, MM | 1 |
| USON, AC | 1 |
| PRICE, TD | 1 |
| MILLER, JA | 2 |
| ENOMOTO, M | 1 |
| CHENG, YS | 1 |
| CHIANG, CM | 1 |
| YAO, T | 1 |
| LAWS, JO | 1 |
| RUDALI, G | 1 |
| ROYER, R | 1 |
| MABILLE, P | 1 |
| DONIACH, I | 1 |
| RUSSELL, DS | 1 |
| BONSER, GM | 1 |
| GREEN, HN | 1 |
| ROSS, HE | 1 |
| HALL, WH | 2 |
| GRIFFIN, AC | 1 |
| COOK, H | 1 |
| CUNNINGHAM, L | 1 |
| ALLISON, JB | 1 |
| WASE, AW | 1 |
| LEATHEM, JH | 2 |
| WAINIO, WW | 1 |
| STASNEY, J | 1 |
| MAUN, ME | 1 |
| MORRIS, HR | 1 |
| WESTFALL, BB | 1 |
| Waddell, WJ | 1 |
| DUNN, TB | 1 |
| DUBNIK, CS | 1 |
| Frith, CH | 1 |
| Littlefield, NA | 1 |
| Umholtz, R | 1 |
| Floyd, RA | 1 |
| Vernie, LN | 1 |
| Poirier, MC | 1 |
| Jacobs, MM | 1 |
| Purchase, IF | 1 |
| Auton, TR | 1 |
| Verna, L | 1 |
| Whysner, J | 1 |
| Williams, GM | 1 |
| Burnouf, D | 1 |
| Miturski, R | 1 |
| Nagao, M | 1 |
| Nakagama, H | 1 |
| Nothisen, M | 1 |
| Wagner, J | 1 |
| Fuchs, RP | 2 |
| Burnouf, DY | 1 |
| van Steeg, H | 1 |
| Meira, LB | 1 |
| Reis, AM | 1 |
| Cheo, DL | 1 |
| Nahari, D | 1 |
| Burns, DK | 1 |
| Friedberg, EC | 1 |
| Gelderblom, WC | 1 |
| Galendo, D | 1 |
| Abel, S | 1 |
| Swanevelder, S | 1 |
| Marasas, WF | 1 |
| Wild, CP | 1 |
| Calvin, M | 1 |
| Sell, S | 1 |
| Becker, FF | 1 |
| Leffert, HL | 1 |
| Watabe, L | 1 |
| Pliss, GB | 1 |
| Khudoley, VV | 1 |
| Sivak, A | 1 |
| Yamamoto, RS | 1 |
| Tomatis, L | 1 |
| Kriek, E | 1 |
| Cohen, SM | 1 |
| Ellwein, LB | 1 |
| Chiang, CL | 1 |
| Conforti, PM | 1 |
| Pero, RW | 1 |
| Seidegård, J | 1 |
| Miller, DG | 1 |
| Gaylor, DW | 1 |
| Chen, JJ | 1 |
| Greenman, DL | 1 |
| Thompson, CH | 1 |
| Baan, RA | 1 |
| Zaalberg, OB | 1 |
| Fichtinger-Schepman, AM | 1 |
| Muysken-Schoen, MA | 1 |
| Lansbergen, MJ | 1 |
| Lohman, PH | 1 |
| Brown, CC | 1 |
| Beland, FA | 1 |
| Kadlubar, FF | 1 |
12 reviews available for 2-acetylaminofluorene and Neoplasms
| Article | Year |
|---|---|
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.
Topics: Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, | 1995 |
Selenium in carcinogenesis.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Cisplatin; Environme | 1984 |
2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenicity Tests; Carcinogens; Cell Division; DNA; Humans; Mice | 1996 |
Molecular approach in cancer epidemiology: early detection of carcinogen-induced mutations in a whole genome (Review).
Topics: 2-Acetylaminofluorene; Carcinogens, Environmental; DNA Adducts; Frameshift Mutation; Genome, Human; | 2000 |
The early detection of frameshift mutations induced by a food-borne carcinogen in rats: a new tool for molecular epidemiology.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; DNA; Food; Frameshift Mutation; Humans; Molecular Epide | 2000 |
The role of nucleotide excision repair and loss of p53 in mutagenesis and carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; DNA Repair; Genes, p53; Humans; Lac Operon; Mutation; Neoplasms | 2001 |
Cancer predisposition in mutant mice defective in multiple genetic pathways: uncovering important genetic interactions.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Disease Models, Animal; DNA Repair; Genes, p53; Genetic | 2001 |
Carcinogenesis.
Topics: 2-Acetylaminofluorene; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Carcinogens; Chemical Phenomena; | 1975 |
Some current perspectives on chemical carcinogenesis in humans and experimental animals: Presidential Address.
Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Biotransformation; Carcinogens; Carcinogens, Environment | 1978 |
Cocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Viral; Cocarcinogenesis; Diet; Gas | 1979 |
The role of hormones on digestive and urinary tract carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Body Weight; Carcinogens; Diet; Female; Food; Gonadal Steroid Hormon | 1976 |
Genetic errors, cell proliferation, and carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Ascorbic Acid; Carcinogens; Cell Division; DNA Replication; Humans; | 1991 |
66 other studies available for 2-acetylaminofluorene and Neoplasms
| Article | Year |
|---|---|
Evaluation of hydro-alcoholic extract of Eclipta alba for its multidrug resistance reversal potential: an in vitro study.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cass | 2013 |
The structure and progression of vesical tumours induced in mice by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Abdominal Cavity; Animals; Disease Progression; Mice; Neoplasms; Tissues; Uri | 1950 |
The histology of pulmonary tumours of the rat induced by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Lung Neoplasms; Neoplasms; Rats | 1947 |
The carcinogenic action of 2-acetylaminofluorene and related compounds.
Topics: 2-Acetylaminofluorene; Carcinogens; Fluorenes; Humans; Neoplasms; Urinary Bladder Neoplasms | 1946 |
Succinoxidase activity of hepatic tumours produced in rats by feeding 2-acetaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Liver; Liver Neoplasms; Neoplasms; Oxidoreductases; Rats | 1947 |
The induction of tumours in mice of the R3 strain by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Fluorenes; Mice; Neoplasms | 1947 |
Production of tumors in rats by 2-aminofluorene and 2-acetylaminofluorene; failure of liver extract and of dietary protein level to influence liver tumor production.
Topics: 2-Acetylaminofluorene; Animals; Diet; Dietary Proteins; Fluorenes; Liver; Liver Extracts; Liver Neop | 1947 |
The induction of neoplasms in five strains of rats with acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Fluorenes; Neoplasms; Neoplasms, Experimental; Rats | 1947 |
Tumors of the salivary and parathyroid glands in rats fed with 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Fluorenes; Neoplasms; Neoplasms, Experimental; Parathyroid Glands; P | 1946 |
2‑Acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Humans; Neoplasms | 2011 |
Semiparametric transformation models for current status data with informative censoring.
Topics: 2-Acetylaminofluorene; Algorithms; Animals; Carcinogens; Dose-Response Relationship, Drug; Female; M | 2012 |
The influence of dietary casein level on tumor induction with 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Caseins; Diet; Neoplasms; Neoplasms, Experimental | 1952 |
Tumors of the liver and urinary bladder of the dog after ingestion of 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Dogs; Fluorenes; Liver; Neoplasms; Urinary Bladder | 1953 |
Studies on the intracellular composition of livers from rats fed 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Fluorenes; Liver; Neoplasms; Nucleic Acids; Proteins; Rats; Riboflav | 1953 |
Studies in 2-acetylaminofluorene carcinogenesis. I. The intracellular distribution of nucleic acids and protein in rat liver.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Fluorenes; Liver; Neoplasms; Neoplasms, Experimental | 1954 |
[Inhibition of 2-acetylaminofluorene tumors in rats with simultaneously fed 20-methylcholanthrene, 9:10-dimethyl-1:2-benzanthracene and chrysene, and consideration of sex difference in tumor genesis with 2-acetyl-aminoflurene].
Topics: 2-Acetylaminofluorene; Animals; Benz(a)Anthracenes; Carcinogens; Chrysenes; Fluorenes; Gonadal Stero | 1953 |
Catalase and uricase studies on rats during 2-acetylaminofluorene carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Catalase; En | 1954 |
Tumors induced by 2-acetylaminofluorene in buffalo-strain rats ingesting different levels of riboflavine.
Topics: 2-Acetylaminofluorene; Animals; Buffaloes; Fluorenes; Neoplasms; Rats; Riboflavin | 1955 |
Cancers of the liver in rat caused by p. dimethylaminoazobenzene and 2. acetylaminofluorene; prophylaxis & pathogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Liver Neoplasms, Experimental; Neoplasms; p-Dimethylami | 1957 |
Localization of radioiodinated antibodies in rats bearing tumors induced by N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Fluorenes; Neoplasms; Rats | 1960 |
The effect of adrenalectomy on the development of tumours induced by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Adrenalectomy; Animals; Fluorenes; Neoplasms; Neoplasms, Experimental | 1961 |
Comparative study of cancer and other lesions of rats fed N.N'-2,7-fluorenylene-bisacetamide or N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Fluorenes; Neoplasms; Rats | 1961 |
Intraocular tumor after ethionine and N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Ethionine; Eye Neoplasms; Fluorenes; Neoplasms; Neoplasms, Experimen | 1962 |
Influence of p-hydroxy-propiophenone on liver tumorigenesis in rats ingesting ethionine and N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Carcinogens; Ethionine; Fluorenes; Hydroxypropiophen | 1963 |
THE METABOLISM OF N-2-FLUORENYLACETAMIDE IN THE RHESUS MONKEY.
Topics: 2-Acetylaminofluorene; Animals; Fluorenes; Haplorhini; Macaca mulatta; Metabolism; Neoplasms; Neopla | 1963 |
CARCINOGENICITY AND METABOLISM OF 2-ACETYLAMINOFLUORENE IN THE RABBIT.
Topics: 2-Acetylaminofluorene; Fluorenes; Kidney; Liver; Metabolism; Neoplasms; Neoplasms, Experimental; Rab | 1963 |
ENDOGENOUS AND EXOGENOUS FACTORS IN CHEMICAL CARCINOGENESIS BY N-2-FLUORENYLACETAMIDE.
Topics: 2-Acetylaminofluorene; Carbon Isotopes; Carcinogenesis; Fluorenes; Liver Neoplasms; Metabolism; Neop | 1963 |
A COMPARISON OF THE PATHOLOGICAL EFFECTS OF 2-ACETYLAMINOFLUORENE, 4-ACETYLAMINOBIPHENYL, AND 2-ACETYLAMINOBIPHENYL IN THE DOG.
Topics: 2-Acetylaminofluorene; Amines; Aminobiphenyl Compounds; Biphenyl Compounds; Carcinogens; Carcinoma, | 1963 |
BLADDER TUMOR INDUCTION IN RATS FED 2-ACETAMIDOFLUORENE (2-AAF) AND A PYRIDOXINE-DEFICIENT DIET.
Topics: 2-Acetylaminofluorene; Carcinogens; Diet; Fluorenes; Liver; Liver Cirrhosis; Liver Cirrhosis, Experi | 1964 |
THE COMPARATIVE CARCINOGENICITIES OF 2-ACETYLAMINOFLUORENE AND ITS N-HYDROXY METABOLITE IN MICE, HAMSTERS, AND GUINEA PIGS.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cricetinae; Croton Oil; Fluorenes; Guinea Pigs; Injecti | 1964 |
[THE EFFECTS OF DIET AND DOSAGE OF CARCINOGEN ON THE INDUCTION OF LIVER TUMORS IN RATS FED 2-ACETYLAMINOFLUORENE].
Topics: 2-Acetylaminofluorene; Carcinogens; Carcinoma, Hepatocellular; Diet; Fluorenes; Liver Neoplasms; Neo | 1965 |
The early changes produced in the auditory sebaceous gland (Zymbal's gland) of the rat by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Ear, External; Fluorenes; Hyperplasia; Hypertrophy; Neoplasms; Rats; | 1955 |
Studies on the enzymatic synthesis of p-aminohippuric acid by the liver of rats fed 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Fluorenes; Liver; Neoplasms; p-Aminohippuric Acid; Rats | 1955 |
The effect of radioactive iodine alone and in combination with methylthiouracil and acetylaminofluorene upon tumour production in the rat's thyroid gland.
Topics: 2-Acetylaminofluorene; Adenoma; Iodine; Iodine Compounds; Lymphoma, Non-Hodgkin; Methylthiouracil; N | 1950 |
Primary tumours of the brain and meninges in rats fed 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Brain; Carcinogens; Meninges; Neoplasms; Rats | 1950 |
Epithelial neoplastic changes in the urinary tract of rabbits induced by feeding with 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Fluorenes; Neoplasms; Rabbits; Urinary Tract | 1950 |
Influence of diet on the relative incidence of eye, mammary, ear-duct, and liver tumors in rats fed 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Diet; Dietetics; Incidence; Liver Neoplasms; Neoplasms; Nutritional | 1951 |
Further studies on the recovery of 2-acetylaminofluorene from rats following oral administration.
Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Neoplasms; Rats | 1951 |
Carcinogenesis in parabiotic rats; tumours of liver and seminal vesicle induced by acetylaminofluorene in normal males joined to castrated males or females.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Female; Humans; Liver Neoplasms; Male; Neoplasms; Ra | 1951 |
Protective action of stock diets against the cancer-inducing action of 2-acetylaminofluorene in rats.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Diet; Neoplasms; Rats | 1952 |
Tissue proteins and carcinogenesis; precancerous changes in the liver and serum proteins of rats fed acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Blood Proteins; Carcinogenesis; Fluorenes; Liver; Neoplasms; Rats | 1949 |
Some effects of 2-acetylaminofluorene on the dog.
Topics: 2-Acetylaminofluorene; Animals; Dogs; Neoplasms | 1950 |
Effect of partial ablation of the bone marrow and of splenectomy on the hepatic lesions produced by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Bone Marrow; Humans; Liver; Neoplasms; Splenectomy | 1950 |
The effect of added dietary tryptophane on the occurrence of 2-acetylaminofluorene-induced liver and bladder cancer in rats.
Topics: 2-Acetylaminofluorene; Animals; Diet; Liver; Neoplasms; Rats; Tryptophan; Urinary Bladder Neoplasms | 1950 |
Some studies of the excretion of diazotizable material after feeding 2-acetylaminofluorene to rats.
Topics: 2-Acetylaminofluorene; Animals; Fluorides; Neoplasms; Rats | 1950 |
Comparisons of thresholds for carcinogenicity on linear and logarithmic dosage scales.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; E | 2005 |
Plasma and Liver Protein Levels in Rats Fed the Carcinogen 2-Acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Fluorenes; Liver; Neoplasms; Rats | 1949 |
The role of initiating and promoting factors in the pathogenesis of tumors of the thyroid.
Topics: 2-Acetylaminofluorene; Animals; Neoplasms; Rats; Thyroid Gland; Thyroid Neoplasms | 1948 |
Two transplantable rat carcinomas induced with N-acetyl-2-aminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Neoplasms; Rats | 1948 |
Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Adenocarcinoma; Animals; Carcinogens; Female; Fibrosarcoma; Kidney Neoplasms; | 1981 |
Free-radical events in chemical and biochemical reactions involving carcinogenic arylamines.
Topics: 2-Acetylaminofluorene; Animals; Electron Spin Resonance Spectroscopy; Enzyme Activation; Female; Flu | 1981 |
The use of antibodies to detect carcinogen - DNA adducts in vivo and in vitro.
Topics: 2-Acetylaminofluorene; Animals; Benzopyrenes; Carcinogens; Cisplatin; DNA; Immune Sera; Liver; Neopl | 1983 |
Effects of selenium on chemical carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Butylated Hydroxytolue | 1980 |
Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules.
Topics: 2-Acetylaminofluorene; Aflatoxins; Allylbenzene Derivatives; Animals; Anisoles; Biotransformation; C | 1981 |
Thresholds in chemical carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenicity Tests; Carcinogens; Dose-Response Relationship, Drug | 1995 |
Cancer initiation by fumonisin B(1) in rat liver--role of cell proliferation.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carboxylic Acids; Carcinogens; Cell Division; | 2001 |
Expression of an oncodevelopmental gene product (alpha-fetoprotein) during fetal development and adult oncogenesis.
Topics: 2-Acetylaminofluorene; Age Factors; alpha-Fetoproteins; Animals; Animals, Newborn; Carcinoma, Hepato | 1976 |
Tumor induction by carcinogenic agents in aquarium fish.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Adenoma, Bile Duct | 1975 |
Validity and limitations of long-term experimentation in cancer research.
Topics: 2-Acetylaminofluorene; Amines; Animals; Bis(Chloromethyl) Ether; Carcinogens, Environmental; Dichlor | 1977 |
Fifty years of research on N-acetyl-2-aminofluorene, one of the most versatile compounds in experimental cancer research.
Topics: 2-Acetylaminofluorene; Animals; DNA; History, 20th Century; Humans; Immunochemistry; Mutagenesis, Si | 1992 |
A survival model and estimation of time to tumor.
Topics: 2-Acetylaminofluorene; Animals; Female; Humans; Mice; Models, Biological; Neoplasms; Stochastic Proc | 1989 |
Development of biochemical markers sensitive to ecogenetic variation and their use in assessing risk from genotoxic exposures.
Topics: 2-Acetylaminofluorene; Aging; DNA Repair; Genetic Markers; Glutathione Transferase; Humans; Mutagens | 1986 |
Occurrence of tumors among litters of BALB/c female mice.
Topics: 2-Acetylaminofluorene; Age Factors; Animals; Female; Litter Size; Liver Neoplasms; Mice; Mice, Inbre | 1985 |
Use of monoclonal and polyclonal antibodies against DNA adducts for the detection of DNA lesions in isolated DNA and in single cells.
Topics: 2-Acetylaminofluorene; Animals; Antibodies; Antibodies, Monoclonal; Antigen-Antibody Complex; Antine | 1985 |
Statistical aspects of the estimation of human risks.
Topics: 2-Acetylaminofluorene; Carcinogens; Environmental Pollution; Humans; Liver Neoplasms; Models, Biolog | 1985 |
Formation and persistence of arylamine DNA adducts in vivo.
Topics: 1-Naphthylamine; 2-Acetylaminofluorene; 2-Naphthylamine; Amines; Aminobiphenyl Compounds; Animals; B | 1985 |