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2-acetylaminofluorene and Neoplasm Metastasis

2-acetylaminofluorene has been researched along with Neoplasm Metastasis in 9 studies

2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
" In our model, rats subjected to 2-acetylaminofluorene/ partial-hepatectomy followed by aflatoxin injection (APA regimen) developed well-differentiated hepatocholangiocarcinomas."3.75Establishment of cancer cell lines from rat hepatocholangiocarcinoma and assessment of the role of granulocyte-colony stimulating factor and hepatocyte growth factor in their growth, motility and survival. ( Gasbarrini, A; Pani, G; Petersen, BE; Piscaglia, AC; Shupe, TD; Tesori, V, 2009)
"The development from primary focus to metastasis was histologically investigated in 2,7-FAA-induced leukemia in rats."1.29Early metastatic stage of 2,7-FAA-induced leukemia in rats. ( Takayama, S, 1994)
"Pulmonary metastases occurred only in the tubulopleomorphic adenocarcinomas."1.26Morphologic characteristics of benign and malignant renal cell tumors in control and 2-acetylaminofluorene-treated BALB/c female mice. ( Frith, CH; Shinohara, Y, 1980)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Piscaglia, AC1
Shupe, TD1
Pani, G1
Tesori, V1
Gasbarrini, A1
Petersen, BE1
Kloppel, TM2
Morré, DJ2
Frith, CH2
Farmer, JH1
Greenman, DL1
Shaw, GW1
Shinohara, Y1
Takayama, S3
Fujiwara, M2
Jacobsen, LB1
Reuber, MD1

Other Studies

9 other studies available for 2-acetylaminofluorene and Neoplasm Metastasis

ArticleYear
Establishment of cancer cell lines from rat hepatocholangiocarcinoma and assessment of the role of granulocyte-colony stimulating factor and hepatocyte growth factor in their growth, motility and survival.
    Journal of hepatology, 2009, Volume: 51, Issue:1

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Move

2009
Characteristics of transplantable tumors induced in the rat by N-2-fluorenylacetamide: elevations in tissue and serum sialic acid.
    Journal of the National Cancer Institute, 1980, Volume: 64, Issue:6

    Topics: 2-Acetylaminofluorene; Animals; Gangliosides; Liver Neoplasms, Experimental; Male; Neoplasm Metastas

1980
Biologic and morphologic characteristics of urinary bladder neoplasms induced in BALB/c female mice with 2-acetylaminofluorene.
    Journal of environmental pathology and toxicology, 1980, Volume: 3, Issue:3 Spec No

    Topics: 2-Acetylaminofluorene; Animals; Female; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasms, E

1980
Morphologic characteristics of benign and malignant renal cell tumors in control and 2-acetylaminofluorene-treated BALB/c female mice.
    The American journal of pathology, 1980, Volume: 100, Issue:2

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenoma; Animals; Carcinoma, Papillary; Cystadenoma; Female;

1980
Early metastatic stage of 2,7-FAA-induced leukemia in rats.
    Pathology international, 1994, Volume: 44, Issue:2

    Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Bone Marrow; Female; Leukemia, Experimental; L

1994
Hematogenous development of rat mature granulocytic leukemia--comparison of 2,7-FAA-induced and transplanted leukemia.
    Acta pathologica japonica, 1978, Volume: 28, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Female; Fluorenes; Leukemia, Experimental; Leukemia, Myeloid; Male;

1978
Hematogenous development of rat mature granulocytic leukemia--distribution of leukemic foci in vertebral bodies.
    Acta pathologica japonica, 1978, Volume: 28, Issue:5

    Topics: 2-Acetylaminofluorene; Animals; Bone Marrow; Female; Leukemia, Experimental; Leukemia, Myeloid; Male

1978
Ganglioside patterns of metastatic and non-metastatic transplantable hepatocellular carcinomas of the rat.
    Journal of supramolecular structure, 1979, Volume: 11, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Gangliosides; Liver Neoplasms; Liver Regeneration; Male; Membrane Li

1979
Carcinoma and cirrhosis of the liver in A X C male rats with one kidney ingesting 0.025% N-2-fluorenyldiacetamide.
    Pathologia et microbiologia, 1975, Volume: 42, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Carcinoma; Carcinosarcoma; Diet; Fluorenes; Kidney; Liver Cirrhosis,

1975