2-acetylaminofluorene has been researched along with Necrosis in 5 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ito, Y | 1 |
| Watanabe, T | 1 |
| Nagatomo, S | 1 |
| Seki, T | 1 |
| Niimi, S | 1 |
| Ariga, T | 1 |
| Ghoshal, AK | 1 |
| Mullen, B | 1 |
| Medline, A | 1 |
| Farber, E | 1 |
| Ho, YS | 1 |
| Lin, JK | 1 |
| Tessitore, L | 1 |
| Pani, P | 1 |
| Dianzani, MU | 1 |
| Shima, H | 1 |
| Kuniyasu, T | 1 |
| Sugie, S | 1 |
| Tanaka, T | 1 |
| Mori, H | 1 |
| Takahashi, M | 1 |
| Muto, Y | 1 |
5 other studies available for 2-acetylaminofluorene and Necrosis
| Article | Year |
|---|---|
Annexin A3-expressing cellular phenotypes emerge from necrotic lesion in the pericentral area in 2-acetylaminofluoren/carbon tetrachloride-treated rat livers.
Topics: 2-Acetylaminofluorene; Alanine Transaminase; Animals; Annexin A3; Aspartate Aminotransferases; Bone | 2007 |
Sequential analysis of hepatic carcinogenesis. Regeneration of liver after carbon tetrachloride-induced liver necrosis when hepatocyte proliferation is inhibited by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Division; Liver; Liver Neoplasms; Liver R | 1983 |
N-nitroso-2-acetylaminofluorene: a direct-acting carcinogen inducing hepatocellular carcinoma in Sprague-Dawley rats.
Topics: 2-Acetylaminofluorene; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Body | 1994 |
Mechanisms of the enhanced liver carcinogenesis by choline in female rats: delay in liver growth after partial hepatectomy and stimulation of 2-AAF mitoinhibition.
Topics: 2-Acetylaminofluorene; Animals; Cell Division; Choline; Diethylnitrosamine; DNA, Neoplasm; Drug Inte | 1992 |
Inhibitory effects of polyprenoic acid (E-5166) on N-2-fluorenylacetamide-initiated hepatocarcinogenesis in rats.
Topics: 2-Acetylaminofluorene; Animals; Body Weight; Drug Antagonism; Liver; Liver Neoplasms, Experimental; | 1986 |