2-acetylaminofluorene has been researched along with Melanoma in 2 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, SY | 1 |
| Yang, JH | 1 |
| Hsia, TC | 1 |
| Lee, JH | 1 |
| Chiu, TH | 1 |
| Wei, YH | 1 |
| Chung, JG | 1 |
| Zimmerman, RJ | 1 |
| Little, JB | 1 |
2 other studies available for 2-acetylaminofluorene and Melanoma
| Article | Year |
|---|---|
Effect of inhibition of aloe-emodin on N-acetyltransferase activity and gene expression in human malignant melanoma cells (A375.S2).
Topics: 2-Acetylaminofluorene; Anthraquinones; Arylamine N-Acetyltransferase; Cell Line, Tumor; Dose-Respons | 2005 |
Characteristics of human diploid fibroblasts transformed in vitro by chemical carcinogens.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Calcium; Cell Division; Cell Transformat | 1983 |