2-acetylaminofluorene has been researched along with Lymphoma in 3 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In previously described activation systems [Clive D, Spector JFS (1975): Mutat Res 31:17-29] for the mouse lymphoma mutation assay the cofactor isocitrate is rapidly exhausted and the resultant loss of NADPH can halt metabolic processes." | 3.68 | Development of an optimal S9 activation mixture for the L5178Y TK+/- mouse lymphoma mutation assay. ( Majeska, JB; Matheson, DW, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoogervorst, EM | 1 |
| Bruins, W | 1 |
| Zwart, E | 1 |
| van Oostrom, CT | 1 |
| van den Aardweg, GJ | 1 |
| Beems, RB | 1 |
| van den Berg, J | 1 |
| Jacks, T | 1 |
| van Steeg, H | 1 |
| de Vries, A | 1 |
| Storer, RD | 1 |
| Cartwright, ME | 1 |
| Cook, WO | 1 |
| Soper, KA | 1 |
| Nichols, WW | 1 |
| Majeska, JB | 1 |
| Matheson, DW | 1 |
3 other studies available for 2-acetylaminofluorene and Lymphoma
| Article | Year |
|---|---|
Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; DNA Damage; Female; Genes, p53; Lymphoma; Male; Mice; M | 2005 |
Short-term carcinogenesis bioassay of genotoxic procarcinogens in PIM transgenic mice.
Topics: 2-Acetylaminofluorene; Animals; Benzene; Biotransformation; Body Weight; Carcinogenicity Tests; Carc | 1995 |
Development of an optimal S9 activation mixture for the L5178Y TK+/- mouse lymphoma mutation assay.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; | 1990 |