2-acetylaminofluorene has been researched along with Lung Neoplasms in 18 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Other malignant neoplasms, including leiomyosarcomas, granulosa cells tumors, adrenocortical carcinomas, angiosarcomas, squamous cell carcinomas, and harderian gland tumors, metastasized at an incidence of less than 5%." | 1.26 | Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide. ( Frith, CH; Littlefield, NA; Umholtz, R, 1981) |
| "Osteosarcomas were found in 16 of 24,192 (0." | 1.26 | Osteosarcomas in BALB/c female mice. ( Frith, CH; Highman, B; Johnson, BP, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (66.67) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Morsy, HM | 1 |
| Ahmed, OM | 1 |
| Zoheir, KMA | 1 |
| Abdel-Moneim, A | 1 |
| ORR, JW | 1 |
| BIELSCHOWSKY, F | 1 |
| Cheo, DL | 2 |
| Friedberg, EC | 2 |
| FISCHER, W | 1 |
| Zhang, Z | 1 |
| Sun, J | 1 |
| Sun, L | 1 |
| Frith, CH | 2 |
| Littlefield, NA | 1 |
| Umholtz, R | 1 |
| Maeura, Y | 1 |
| Williams, GM | 1 |
| Hoch-Ligeti, C | 1 |
| Harris, PN | 1 |
| Stewart, HL | 1 |
| Johnson, BP | 1 |
| Highman, B | 1 |
| Wang, YJ | 1 |
| Ho, YS | 1 |
| Lo, MJ | 1 |
| Lin, JK | 1 |
| Wang, Y | 2 |
| Stoner, G | 1 |
| You, M | 1 |
| Burns, DK | 1 |
| Meira, LB | 1 |
| Houle, JF | 1 |
| Sivak, A | 1 |
| Pozharisskiĭ, KM | 1 |
| Tomatis, L | 1 |
| Tsuda, H | 2 |
| Ogiso, T | 2 |
| Hasegawa, R | 1 |
| Imaida, K | 1 |
| Masui, T | 1 |
| Ito, N | 2 |
| Greenman, DL | 1 |
| Boothe, A | 1 |
| Kodell, R | 1 |
| Shirai, T | 1 |
| Hirose, M | 1 |
2 reviews available for 2-acetylaminofluorene and Lung Neoplasms
| Article | Year |
|---|---|
Cocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Viral; Cocarcinogenesis; Diet; Gas | 1979 |
[Successes of experimental oncology and problems of the study of the morphogenesis of tumors].
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Azoxymethane; Benzopyr | 1975 |
16 other studies available for 2-acetylaminofluorene and Lung Neoplasms
| Article | Year |
|---|---|
The anticarcinogenic effect of eugenol on lung cancer induced by diethylnitrosamine/2-acetylaminofluorene in Wistar rats: insight on the mechanisms of action.
Topics: 2-Acetylaminofluorene; Animals; Anticarcinogenic Agents; Apoptosis; Diethylnitrosamine; Eugenol; Liv | 2023 |
The histology of pulmonary tumours of the rat induced by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Lung Neoplasms; Neoplasms; Rats | 1947 |
Use of nucleotide excision repair-deficient mice as a model for chemically induced lung cancer.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cocarcinogenesis; Crosses, Genetic; Disease Models, Ani | 2003 |
[On lung changes and lung tumors in rats after administration of acetylaminofluorene].
Topics: 2-Acetylaminofluorene; Animals; Fluorenes; Lung Neoplasms; Neoplasms, Experimental; Rats | 1960 |
Statistical analysis of current status data with informative observation times.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenicity Tests; Carcinogens; Computer Simulation; Female; Lun | 2005 |
Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Adenocarcinoma; Animals; Carcinogens; Female; Fibrosarcoma; Kidney Neoplasms; | 1981 |
Enhancing effect of butylated hydroxytoluene on the development of liver altered foci and neoplasms induced by N-2-fluorenylacetamide in rats.
Topics: 2-Acetylaminofluorene; Animals; Butylated Hydroxytoluene; Diet; Dose-Response Relationship, Drug; Dr | 1984 |
Endocardial tumors induced by carbamate or fluorenylacetamide derivatives in rats.
Topics: 2-Acetylaminofluorene; Animals; Carbamates; Diagnosis, Differential; Endocarditis; Endocardium; Fema | 1983 |
Osteosarcomas in BALB/c female mice.
Topics: 2-Acetylaminofluorene; Animals; Bone Neoplasms; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; O | 1982 |
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
Topics: 2-Acetylaminofluorene; Adenine; Aging; Animals; Antineoplastic Agents; Disease Models, Animal; DNA D | 1995 |
ras mutations in 2-acetylaminofluorene-induced lung and liver tumors from C3H/HeJ and (C3H x A/J)F1 mice.
Topics: 2-Acetylaminofluorene; Animals; Base Sequence; Codon; DNA Mutational Analysis; Female; Genes, ras; L | 1993 |
Mutational inactivation of the xeroderma pigmentosum group C gene confers predisposition to 2-acetylaminofluorene-induced liver and lung cancer and to spontaneous testicular cancer in Trp53-/- mice.
Topics: 2-Acetylaminofluorene; Animals; DNA Repair; Female; Genes, p53; Humans; Liver Neoplasms, Experimenta | 1999 |
Validity and limitations of long-term experimentation in cancer research.
Topics: 2-Acetylaminofluorene; Amines; Animals; Bis(Chloromethyl) Ether; Carcinogens, Environmental; Dichlor | 1977 |
Inhibition of neoplastic development in rat liver, kidney, oesophagus and forestomach by 4,4'-diaminodiphenylmethane administration.
Topics: 2-Acetylaminofluorene; Aniline Compounds; Animals; Esophageal Neoplasms; Kidney Neoplasms; Liver Neo | 1987 |
Age-dependent responses to 2-acetylaminofluorene in BALB/c female mice.
Topics: 2-Acetylaminofluorene; Aging; Animals; Body Weight; Environment; Female; Liver Neoplasms; Liver Neop | 1987 |
Organ specific modifying potential of ethinyl estradiol on carcinogenesis initiated with different carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Interactio | 1987 |