2-acetylaminofluorene has been researched along with Liver Steatosis in 1 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Groups of 28 week old DIO and LEAN mice were dosed with the bioactivation-dependent DNA-reactive hepatocarcinogen 2-acetylaminofluorene (AAF), at 2." | 1.39 | Hepatocellular proliferation and hepatocarcinogen bioactivation in mice with diet-induced fatty liver and obesity. ( Duan, JD; Hayes, AN; Iatropoulos, MJ; Jeffrey, AM; Leach, MW; Stedman, NL; Williams, GM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iatropoulos, MJ | 1 |
| Duan, JD | 1 |
| Jeffrey, AM | 1 |
| Leach, MW | 1 |
| Hayes, AN | 1 |
| Stedman, NL | 1 |
| Williams, GM | 1 |
1 other study available for 2-acetylaminofluorene and Liver Steatosis
| Article | Year |
|---|---|
Hepatocellular proliferation and hepatocarcinogen bioactivation in mice with diet-induced fatty liver and obesity.
Topics: 2-Acetylaminofluorene; Animal Feed; Animals; Carcinogens; Cell Proliferation; Diet, Fat-Restricted; | 2013 |