2-acetylaminofluorene has been researched along with Leukemia L5178 in 3 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Leukemia L5178: An experimental lymphocytic leukemia of mice.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oberly, TJ | 1 |
| Piper, CE | 1 |
| McDonald, DS | 1 |
| Amacher, DE | 1 |
| Paillet, SC | 1 |
| Elliott, JA | 1 |
| Rogers, AM | 1 |
| Hill, R | 1 |
| Lehmann, AR | 1 |
| Arlett, CF | 1 |
| Burns, VW | 1 |
3 other studies available for 2-acetylaminofluorene and Leukemia L5178
| Article | Year |
|---|---|
Metabolic activation capabilities of S9 liver fraction from 3 species in the L5178Y mouse-lymphoma assay.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Cricetinae; Leu | 1982 |
The metabolism of N-acetyl-2-aminofluorene to a mutagen in L5178Y/TK+/-mouse lymphoma cells.
Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Dose-Response Relationship, Drug; Leukemia L5178; | 1981 |
The induction and characterization of mouse lymphoma L5178Y cell lines resistant to 1-beta-d-arabinofuranosylcytosine.
Topics: 2-Acetylaminofluorene; Animals; Cell Line; Cytarabine; Drug Resistance; Ethidium; Ethyl Methanesulfo | 1980 |