2-acetylaminofluorene has been researched along with Leukemia L 1210 in 2 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aloe-emodin has been shown to exit anticancer activity." | 5.32 | Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells. ( Chang, WC; Cheng, KC; Chung, JG; Lee, YM; Li, YC; Lin, JP, 2003) |
| "Aloe-emodin has been shown to exit anticancer activity." | 1.32 | Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells. ( Chang, WC; Cheng, KC; Chung, JG; Lee, YM; Li, YC; Lin, JP, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chung, JG | 1 |
| Li, YC | 1 |
| Lee, YM | 1 |
| Lin, JP | 1 |
| Cheng, KC | 1 |
| Chang, WC | 1 |
| Lesca, P | 1 |
| Beaune, P | 1 |
| Monsarrat, B | 1 |
2 other studies available for 2-acetylaminofluorene and Leukemia L 1210
| Article | Year |
|---|---|
Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells.
Topics: 2-Acetylaminofluorene; Acetylation; Animals; Anthraquinones; Arylamine N-Acetyltransferase; Chromato | 2003 |
Ellipticines and human liver microsomes: spectral interaction with cytochrome P-450 and hydroxylation. Inhibition of aryl hydrocarbon metabolism and mutagenicity.
Topics: 2-Acetylaminofluorene; Adult; Alkaloids; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxy | 1981 |