2-acetylaminofluorene and Leucocythaemia studies

2-acetylaminofluorene and Leucocythaemia

2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

Research Excerpts

Excerpt	Relevance	Reference
" The purpose of this present study is to evaluate the question of whether luteolin could affect arylamine N-acetyltransferase (NAT) activity and DNA-2-aminofluorene adduct formation in human (HL-60) and mouse (L1210) leukemia cells."	7.71	Luteolin-inhibited arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human and mouse leukemia cells. ( Chung, JG; Hung, CF; Li, YC; Lin, JP; Yeh, FT, 2001)
" The purpose of this present study is to evaluate the question of whether luteolin could affect arylamine N-acetyltransferase (NAT) activity and DNA-2-aminofluorene adduct formation in human (HL-60) and mouse (L1210) leukemia cells."	3.71	Luteolin-inhibited arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human and mouse leukemia cells. ( Chung, JG; Hung, CF; Li, YC; Lin, JP; Yeh, FT, 2001)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (50.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

1 (50.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

1 (50.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Vernie, LN	1
Li, YC	1
Hung, CF	1
Yeh, FT	1
Lin, JP	1
Chung, JG	1

Studies

Vernie, LN

Li, YC

Hung, CF

Yeh, FT

Lin, JP

Chung, JG

Reviews

1 review available for 2-acetylaminofluorene and Leucocythaemia

Article	Year
Selenium in carcinogenesis. Biochimica et biophysica acta, 1984, Volume: 738, Issue:4 Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Cisplatin; Environme	1984

Article

Year

Selenium in carcinogenesis.

Biochimica et biophysica acta, 1984, Volume: 738, Issue:4

Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Cisplatin; Environme

1984

Other Studies

1 other study available for 2-acetylaminofluorene and Leucocythaemia

Article	Year
Luteolin-inhibited arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human and mouse leukemia cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2001, Volume: 39, Issue:7 Topics: 2-Acetylaminofluorene; Acetylation; Animals; Arylamine N-Acetyltransferase; Cytosol; DNA Adducts; Do	2001

Article

Year

Luteolin-inhibited arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human and mouse leukemia cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2001, Volume: 39, Issue:7

Topics: 2-Acetylaminofluorene; Acetylation; Animals; Arylamine N-Acetyltransferase; Cytosol; DNA Adducts; Do

2001