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2-acetylaminofluorene and Kidney Neoplasms

2-acetylaminofluorene has been researched along with Kidney Neoplasms in 10 studies

2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

Kidney Neoplasms: Tumors or cancers of the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
" Two diets used widely in toxicological and/or nutritional studies, and considered to be nutritionally adequate, were compared with respect to their influence on growth, body weight, lifespan, spontaneous neoplasia, and neoplastic responses to 2-acetylaminofluorene (2-AAF)."3.68Effects of diet type on incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors in BALB/c mice fed AIN-76A diet versus NIH-07 diet. ( Bucci, TJ; Fullerton, FR; Greenman, DL, 1992)
"Other malignant neoplasms, including leiomyosarcomas, granulosa cells tumors, adrenocortical carcinomas, angiosarcomas, squamous cell carcinomas, and harderian gland tumors, metastasized at an incidence of less than 5%."1.26Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide. ( Frith, CH; Littlefield, NA; Umholtz, R, 1981)
"Pulmonary metastases occurred only in the tubulopleomorphic adenocarcinomas."1.26Morphologic characteristics of benign and malignant renal cell tumors in control and 2-acetylaminofluorene-treated BALB/c female mice. ( Frith, CH; Shinohara, Y, 1980)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19907 (70.00)18.7374
1990's3 (30.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frith, CH2
Littlefield, NA1
Umholtz, R1
Althoff, J1
Chesterman, FC1
Shinohara, Y1
Blanck, A1
Assefaw-Redda, Y1
Eriksson, LC1
Gustafsson, JA1
Ekvärn, S1
Hällström, IP1
Hagiwara, A1
Tanaka, H1
Imaida, K2
Tamano, S1
Fukushima, S1
Ito, N3
Yamamoto, RS1
Weisburger, EK1
Reuber, MD1
Fullerton, FR1
Greenman, DL1
Bucci, TJ1
Tsuda, H2
Ogiso, T2
Hasegawa, R1
Masui, T1
Shirai, T1
Hirose, M1

Reviews

1 review available for 2-acetylaminofluorene and Kidney Neoplasms

ArticleYear
The role of hormones on digestive and urinary tract carcinogenesis.
    Recent progress in hormone research, 1976, Volume: 33

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Carcinogens; Diet; Female; Food; Gonadal Steroid Hormon

1976

Other Studies

9 other studies available for 2-acetylaminofluorene and Kidney Neoplasms

ArticleYear
Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:4

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Animals; Carcinogens; Female; Fibrosarcoma; Kidney Neoplasms;

1981
Tumours of the urinary bladder, renal pelvis, ureter and urethra.
    IARC scientific publications, 1982, Issue:34

    Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cricetinae; Diethylstilbestrol; Humans; Kidney Neoplasm

1982
Morphologic characteristics of benign and malignant renal cell tumors in control and 2-acetylaminofluorene-treated BALB/c female mice.
    The American journal of pathology, 1980, Volume: 100, Issue:2

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenoma; Animals; Carcinoma, Papillary; Cystadenoma; Female;

1980
Growth hormone administration after treatment in the resistant hepatocyte model does not affect progression of rat liver carcinogenesis.
    Cancer letters, 1994, May-16, Volume: 79, Issue:2

    Topics: 2-Acetylaminofluorene; Androstenedione; Animals; Body Weight; Cell Division; Diethylnitrosamine; Fem

1994
Correlation between medium-term multi-organ carcinogenesis bioassay data and long-term observation results in rats.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Butylated Hydroxyanisole; Carcinogenicity Tests; Carcin

1993
Decreased incidence of renal cell carcinoma in rats with one kidney ingesting N-4-(4'-fluorobiphenyl)acetamide.
    Experientia, 1976, Feb-15, Volume: 32, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Carcinoma; Kidney Neoplasms; Liver Neoplasms; Male; Nep

1976
Effects of diet type on incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors in BALB/c mice fed AIN-76A diet versus NIH-07 diet.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:2

    Topics: 2-Acetylaminofluorene; Adenoma; Animals; Body Weight; Carcinoma, Hepatocellular; Eating; Female; Foo

1992
Inhibition of neoplastic development in rat liver, kidney, oesophagus and forestomach by 4,4'-diaminodiphenylmethane administration.
    Carcinogenesis, 1987, Volume: 8, Issue:5

    Topics: 2-Acetylaminofluorene; Aniline Compounds; Animals; Esophageal Neoplasms; Kidney Neoplasms; Liver Neo

1987
Organ specific modifying potential of ethinyl estradiol on carcinogenesis initiated with different carcinogens.
    Carcinogenesis, 1987, Volume: 8, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Interactio

1987