2-acetylaminofluorene has been researched along with Experimental Leukemia in 10 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The development from primary focus to metastasis was histologically investigated in 2,7-FAA-induced leukemia in rats." | 1.29 | Early metastatic stage of 2,7-FAA-induced leukemia in rats. ( Takayama, S, 1994) |
| "We compared the primary site of mature granulocytic leukemia with that of erythroblastic leukemia." | 1.26 | Site of origin of 2,7-FAA-induced rat leukemia. ( Fujiwara, M; Takayama, S, 1978) |
| "The induction of mature granulocytic leukemia was thought to be increased by the promotion of the granulopoiesis which had been suppressed by 2,7-FAA." | 1.26 | Influence of blood collection on incidence of 2,7-FAA induced rat leukemia. ( Fujiwara, M; Takayama, S, 1976) |
| "The incidence of leukemia and mature granulocytic leukemia became elevated by bloodletting." | 1.26 | Effect of repeated bloodletting on the incidence of 2,7-FAA-induced rat leukemia. ( Fujiwara, M; Takayama, S, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oberly, TJ | 1 |
| Piper, CE | 1 |
| McDonald, DS | 1 |
| Amacher, DE | 1 |
| Paillet, SC | 1 |
| Elliott, JA | 1 |
| Rogers, AM | 1 |
| Hill, R | 1 |
| Lehmann, AR | 1 |
| Arlett, CF | 1 |
| Burns, VW | 1 |
| Takayama, S | 7 |
| Fujiwara, M | 5 |
10 other studies available for 2-acetylaminofluorene and Experimental Leukemia
| Article | Year |
|---|---|
Metabolic activation capabilities of S9 liver fraction from 3 species in the L5178Y mouse-lymphoma assay.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Cricetinae; Leu | 1982 |
The metabolism of N-acetyl-2-aminofluorene to a mutagen in L5178Y/TK+/-mouse lymphoma cells.
Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Dose-Response Relationship, Drug; Leukemia L5178; | 1981 |
The induction and characterization of mouse lymphoma L5178Y cell lines resistant to 1-beta-d-arabinofuranosylcytosine.
Topics: 2-Acetylaminofluorene; Animals; Cell Line; Cytarabine; Drug Resistance; Ethidium; Ethyl Methanesulfo | 1980 |
Early metastatic stage of 2,7-FAA-induced leukemia in rats.
Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Bone Marrow; Female; Leukemia, Experimental; L | 1994 |
Erythroblasts as an index of initial stage of 2,7-FAA, ENU and BNU-induced rat leukemia.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Erythroblasts; Ethylnitrosourea; Female; Leukemia, Expe | 1993 |
Hematogenous development of rat mature granulocytic leukemia--comparison of 2,7-FAA-induced and transplanted leukemia.
Topics: 2-Acetylaminofluorene; Animals; Female; Fluorenes; Leukemia, Experimental; Leukemia, Myeloid; Male; | 1978 |
Site of origin of 2,7-FAA-induced rat leukemia.
Topics: 2-Acetylaminofluorene; Animals; Bone and Bones; Erythroblasts; Female; Fluorenes; Leukemia, Experime | 1978 |
Hematogenous development of rat mature granulocytic leukemia--distribution of leukemic foci in vertebral bodies.
Topics: 2-Acetylaminofluorene; Animals; Bone Marrow; Female; Leukemia, Experimental; Leukemia, Myeloid; Male | 1978 |
Influence of blood collection on incidence of 2,7-FAA induced rat leukemia.
Topics: 2-Acetylaminofluorene; Animals; Animals, Laboratory; Blood Specimen Collection; Female; Fluorenes; L | 1976 |
Effect of repeated bloodletting on the incidence of 2,7-FAA-induced rat leukemia.
Topics: 2-Acetylaminofluorene; Animals; Bloodletting; Female; Fluorenes; Hematopoiesis; Leukemia, Experiment | 1976 |