Page last updated: 2024-11-07

2-acetylaminofluorene and Enlarged Liver

2-acetylaminofluorene has been researched along with Enlarged Liver in 1 studies

2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

Research Excerpts

ExcerptRelevanceReference
" Because the administration of 2-acetylaminofluorene (2AAF) followed by a partial hepatectomy, selectively induces the HPC proliferation, we investigated the effects of chronic 2AAF administration on the HCC development caused by the chronic administration of the carcinogen diethylnitrosamine (DEN) for 16 weeks in the rat."1.62Enrichment of progenitor cells by 2-acetylaminofluorene accelerates liver carcinogenesis induced by diethylnitrosamine in vivo. ( Arellanes-Robledo, J; Castro-Gil, MP; Del-Pozo-Jauner, L; Gabiño-López, NB; López-Torres, CD; Pérez-Carreón, JI; Quintanar-Jurado, V; Sánchez-Rodríguez, R; Torres-Mena, JE; Villa-Treviño, S, 2021)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Castro-Gil, MP1
Sánchez-Rodríguez, R1
Torres-Mena, JE1
López-Torres, CD1
Quintanar-Jurado, V1
Gabiño-López, NB1
Villa-Treviño, S1
Del-Pozo-Jauner, L1
Arellanes-Robledo, J1
Pérez-Carreón, JI1

Other Studies

1 other study available for 2-acetylaminofluorene and Enlarged Liver

ArticleYear
Enrichment of progenitor cells by 2-acetylaminofluorene accelerates liver carcinogenesis induced by diethylnitrosamine in vivo.
    Molecular carcinogenesis, 2021, Volume: 60, Issue:6

    Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Diethyln

2021