2-acetylaminofluorene has been researched along with EHS Tumor in 7 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Other malignant neoplasms, including leiomyosarcomas, granulosa cells tumors, adrenocortical carcinomas, angiosarcomas, squamous cell carcinomas, and harderian gland tumors, metastasized at an incidence of less than 5%." | 1.26 | Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide. ( Frith, CH; Littlefield, NA; Umholtz, R, 1981) |
| "Osteosarcomas were found in 16 of 24,192 (0." | 1.26 | Osteosarcomas in BALB/c female mice. ( Frith, CH; Highman, B; Johnson, BP, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| POIRIER, MM | 1 |
| MILLER, JA | 2 |
| MILLER, EC | 2 |
| Frith, CH | 2 |
| Littlefield, NA | 1 |
| Umholtz, R | 1 |
| Johnson, BP | 1 |
| Highman, B | 1 |
| Allaben, WT | 1 |
| Weeks, CE | 1 |
| Weis, CC | 1 |
| Burger, GT | 1 |
| King, CM | 1 |
| Fuchs, RP | 1 |
| Lang, MC | 1 |
| Chopra, P | 1 |
| Manga, A | 1 |
| Nayak, NC | 1 |
| Kroes, R | 1 |
| Berkvens, JM | 1 |
| Weisburger, JH | 1 |
7 other studies available for 2-acetylaminofluorene and EHS Tumor
| Article | Year |
|---|---|
THE CARCINOGENIC ACTIVITIES OF N-HYDROXY-2-ACETYLAMINOFLUORENE AND ITS METAL CHELATES AS A FUNCTION OF RETENTION AT THE INJECTION SITE.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Chelating Agents; Cobalt; Copper; Fluorenes; Iron; Mamm | 1965 |
Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Adenocarcinoma; Animals; Carcinogens; Female; Fibrosarcoma; Kidney Neoplasms; | 1981 |
Osteosarcomas in BALB/c female mice.
Topics: 2-Acetylaminofluorene; Animals; Bone Neoplasms; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; O | 1982 |
Rat mammary gland carcinogenesis after local injection of N-hydroxy-N-acyl-2-aminofluorenes: relationship to metabolic activation.
Topics: 2-Acetylaminofluorene; Acetyltransferases; Acyltransferases; Adenocarcinoma; Adenofibroma; Animals; | 1982 |
Comparative carcinogenicities and reactivities of N-myristoyloxy-N-acetyl-2-aminofluorene and its 7-iodo derivative.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Chemical Phenomena; Chemistry; DNA; Male; Rats; Sarcoma | 1981 |
Kupffer cell sarcoma in rats after exposure to small doses of dimethylnitrosamine and N-2-acetylaminofluorene during hepatic regeneration.
Topics: 2-Acetylaminofluorene; Animals; Dimethylnitrosamine; Fluorenes; Liver Neoplasms; Liver Regeneration; | 1979 |
Immunosuppression in primary liver and colon tumor induction with N-hydroxy-N-2-fluorenylacetamide and azoxymethane.
Topics: 2-Acetylaminofluorene; Animals; Antilymphocyte Serum; Azoxymethane; Colonic Neoplasms; Hemangiosarco | 1975 |