2-acetylaminofluorene has been researched along with Disease Exacerbation in 11 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Excerpt | Relevance | Reference |
|---|
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomas, NS | 1 |
| George, K | 1 |
| Selvam, AAA | 1 |
| FOULDS, L | 1 |
| Furtado, KS | 1 |
| Pires, PW | 1 |
| Justulin, LA | 1 |
| Rodrigues, MA | 1 |
| Felisbino, SL | 1 |
| Barbisan, LF | 1 |
| Wu, W | 1 |
| Yao, DF | 1 |
| Qiu, LW | 1 |
| Sai, WL | 1 |
| Shen, JJ | 1 |
| Yu, HB | 1 |
| Wu, XH | 1 |
| Li, YM | 1 |
| Wang, YL | 1 |
| Gu, WJ | 1 |
| Shpyleva, SI | 1 |
| Muskhelishvili, L | 1 |
| Tryndyak, VP | 1 |
| Koturbash, I | 1 |
| Tokar, EJ | 1 |
| Waalkes, MP | 1 |
| Beland, FA | 1 |
| Pogribny, IP | 1 |
| Mazzantini, RP | 1 |
| de Conti, A | 1 |
| Moreno, FS | 1 |
| Miki, A | 1 |
| Yano, Y | 1 |
| Kato, H | 1 |
| Seo, Y | 1 |
| Kuriyama, M | 1 |
| Azuma, T | 1 |
| Hayashi, Y | 1 |
| Liao, DZ | 1 |
| Blanck, A | 1 |
| Gustafsson, JA | 1 |
| Hällström, IP | 1 |
| De Miglio, MR | 1 |
| Simile, MM | 1 |
| Muroni, MR | 1 |
| Pusceddu, S | 1 |
| Calvisi, D | 1 |
| Carru, A | 1 |
| Seddaiu, MA | 1 |
| Daino, L | 1 |
| Deiana, L | 1 |
| Pascale, RM | 1 |
| Feo, F | 1 |
| Stål, P | 2 |
| Wang, GS | 2 |
| Olsson, JM | 2 |
| Eriksson, LC | 2 |
11 other studies available for 2-acetylaminofluorene and Disease Exacerbation
| Article | Year |
|---|---|
Troxerutin subdues hepatic tumorigenesis via disrupting the MDM2-p53 interaction.
Topics: 2-Acetylaminofluorene; Animals; Antineoplastic Agents; Apoptosis; Carcinogenesis; Disease Progressio | 2018 |
The structure and progression of vesical tumours induced in mice by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Abdominal Cavity; Animals; Disease Progression; Mice; Neoplasms; Tissues; Uri | 1950 |
Metalloproteinases 2 and 9 activity during promotion and progression stages of rat liver carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Body Weight; Diethylnitrosamine; Disease Progression; Glutathione S- | 2009 |
Characteristics of hepatic nuclear-transcription factor-kappa B expression and quantitative analysis in rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Transformation, N | 2009 |
Chronic administration of 2-acetylaminofluorene alters the cellular iron metabolism in rat liver.
Topics: 2-Acetylaminofluorene; Animals; Antimicrobial Cationic Peptides; Carcinogens; Cation Transport Prote | 2011 |
Persistent and remodeling hepatic preneoplastic lesions present differences in cell proliferation and apoptosis, as well as in p53, Bcl-2 and NF-kappaB pathways.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Cocarcinogenesis; | 2008 |
Anti-tumor effect of pegylated interferon in the rat hepatocarcinogenesis model.
Topics: 2-Acetylaminofluorene; Algorithms; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Diethy | 2008 |
Expression of the c-jun, jun-B, ets-2 and liver regeneration factor-1 (LRF-1) genes during promotion and progression of rat liver carcinogenesis in the resistant hepatocyte model.
Topics: 2-Acetylaminofluorene; Activating Transcription Factor 3; Animals; Carcinogens; Disease Models, Anim | 1996 |
Correlation of c-myc overexpression and amplification with progression of preneoplastic liver lesions to malignancy in the poorly susceptible Wistar rat strain.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Cell Transformation, Neoplastic; Chloroform; Diethylnitro | 1999 |
Effects of dietary iron overload on progression in chemical hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Carcinogens; Carcinoma, Hepatocellular; Cell Division; Ch | 1999 |
Diet restriction increases ubiquinone contents and inhibits progression of hepatocellular carcinoma in the rat.
Topics: 2-Acetylaminofluorene; Animals; Antioxidants; Apoptosis; Carcinogens; Cell Division; Diethylnitrosam | 2000 |