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2-acetylaminofluorene and Chromosome Deletion

2-acetylaminofluorene has been researched along with Chromosome Deletion in 4 studies

2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

Chromosome Deletion: Actual loss of portion of a chromosome.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fuchs, RP2
Schwartz, N1
Daune, MP1
Schaaper, RM1
Koffel-Schwartz, N1
Mah, MC1
Maher, VM1
Thomas, H1
Reid, TM1
King, CM1
McCormick, JJ1
Carothers, AM1
Urlaub, G1
Steigerwalt, RW1
Chasin, LA1
Grunberger, D1

Other Studies

4 other studies available for 2-acetylaminofluorene and Chromosome Deletion

ArticleYear
Hot spots of frameshift mutations induced by the ultimate carcinogen N-acetoxy-N-2-acetylaminofluorene.
    Nature, 1981, Dec-17, Volume: 294, Issue:5842

    Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Base Sequence; Chromosome Deletion; DNA Replicati

1981
N-acetoxy-N-acetyl-2-aminofluorene-induced mutagenesis in the lacI gene of Escherichia coli.
    Carcinogenesis, 1990, Volume: 11, Issue:7

    Topics: 2-Acetylaminofluorene; Bacterial Proteins; Base Sequence; Chromosome Aberrations; Chromosome Deletio

1990
Mutations induced by aminofluorene-DNA adducts during replication in human cells.
    Carcinogenesis, 1989, Volume: 10, Issue:12

    Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Bacterial Proteins; Base Sequence; Carcinogens; C

1989
Characterization of mutations induced by 2-(N-acetoxy-N-acetyl)aminofluorene in the dihydrofolate reductase gene of cultured hamster cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:17

    Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Base Sequence; Cell Line; Chemical Pheno

1986