2-acetylaminofluorene has been researched along with Cholangioma in 4 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "03% 2-acetylaminofluorene (AAF) resulted, 12 to 15 months later, in a massive production of hepatic cysts." | 7.66 | Hepatic cyst formation in male rats partially hepatectomized as weanlings during short-term feeding of 2-acetylaminofluorene. ( Pitot, HC; Potter, VR; Richards, WL, 1982) |
| "03% 2-acetylaminofluorene (AAF) resulted, 12 to 15 months later, in a massive production of hepatic cysts." | 3.66 | Hepatic cyst formation in male rats partially hepatectomized as weanlings during short-term feeding of 2-acetylaminofluorene. ( Pitot, HC; Potter, VR; Richards, WL, 1982) |
| "Well to moderately well differentiated hepatocellular carcinomas developed in 50% and 75% of rats fed the CD + AAF diet for 4 and 6 months, respectively." | 1.26 | Enhancement of 2-acetylaminofluorene liver carcinogenesis in rats fed a choline-devoid diet. ( Lombardi, B; Shinozuka, H, 1979) |
| "These neoplasms included cholangiomas, hepatoadenomas, cholangiocarcinomas, and hepatocellular cancers." | 1.25 | Tumor induction by carcinogenic agents in aquarium fish. ( Khudoley, VV; Pliss, GB, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Richards, WL | 1 |
| Pitot, HC | 1 |
| Potter, VR | 1 |
| Pliss, GB | 1 |
| Khudoley, VV | 1 |
| Matsushima, T | 1 |
| Sugimura, T | 1 |
| Lombardi, B | 1 |
| Shinozuka, H | 1 |
1 review available for 2-acetylaminofluorene and Cholangioma
| Article | Year |
|---|---|
Experimental carcinogenesis in small aquarium fishes.
Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; | 1976 |
3 other studies available for 2-acetylaminofluorene and Cholangioma
| Article | Year |
|---|---|
Hepatic cyst formation in male rats partially hepatectomized as weanlings during short-term feeding of 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Adenoma, Bile Duct; Animals; Chemical and Drug Induced Liver Injury; Cysts; H | 1982 |
Tumor induction by carcinogenic agents in aquarium fish.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Adenoma, Bile Duct | 1975 |
Enhancement of 2-acetylaminofluorene liver carcinogenesis in rats fed a choline-devoid diet.
Topics: 2-Acetylaminofluorene; Adenoma, Bile Duct; Animals; Bile Duct Neoplasms; Carcinoma, Hepatocellular; | 1979 |