2-acetylaminofluorene has been researched along with Cholangiocarcinoma in 2 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Cholangiocarcinoma: A malignant tumor arising from the epithelium of the BILE DUCTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In our model, rats subjected to 2-acetylaminofluorene/ partial-hepatectomy followed by aflatoxin injection (APA regimen) developed well-differentiated hepatocholangiocarcinomas." | 3.75 | Establishment of cancer cell lines from rat hepatocholangiocarcinoma and assessment of the role of granulocyte-colony stimulating factor and hepatocyte growth factor in their growth, motility and survival. ( Gasbarrini, A; Pani, G; Petersen, BE; Piscaglia, AC; Shupe, TD; Tesori, V, 2009) |
| "A rat cell line-nominated CC-62 derived from a combined hepatocellular and cholangiocellular carcinoma obtained by administration of 2-acetylaminofluorene to male Wistar rats, has been established." | 3.71 | Characterization of a new rat cell line established from 2'AAF-induced combined hepatocellular cholangiocellular carcinoma. ( Callaghan, R; Carda, C; Gil-Benso, R; Gregori-Romero, MA; Llombart-Bosch, A; Martinez-Lorente, A; Navarro-Fos, S; Pellin-Perez, A; Peydro-Olaya, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piscaglia, AC | 1 |
| Shupe, TD | 1 |
| Pani, G | 1 |
| Tesori, V | 1 |
| Gasbarrini, A | 1 |
| Petersen, BE | 1 |
| Gil-Benso, R | 1 |
| Martinez-Lorente, A | 1 |
| Pellin-Perez, A | 1 |
| Navarro-Fos, S | 1 |
| Gregori-Romero, MA | 1 |
| Carda, C | 1 |
| Callaghan, R | 1 |
| Peydro-Olaya, A | 1 |
| Llombart-Bosch, A | 1 |
2 other studies available for 2-acetylaminofluorene and Cholangiocarcinoma
| Article | Year |
|---|---|
Establishment of cancer cell lines from rat hepatocholangiocarcinoma and assessment of the role of granulocyte-colony stimulating factor and hepatocyte growth factor in their growth, motility and survival.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Move | 2009 |
Characterization of a new rat cell line established from 2'AAF-induced combined hepatocellular cholangiocellular carcinoma.
Topics: 2-Acetylaminofluorene; Aneuploidy; Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma | 2001 |