2-acetylaminofluorene has been researched along with Cell Transformation, Neoplastic in 71 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Activation of ras protooncogenes in 11 2-acetylaminofluorene (AAF)-induced hepatocellular carcinomas (HCCs) or liver cell lines and 9 3'-methyl-(dimethylamino)azobenzene (3'-Me-DAB)-induced HCCs in rats was examined using the NIH3T3 cell transfection assay and oligonucleotide hybridization analysis." | 7.68 | Low frequency of ras activation in 2-acetylaminofluorene- and 3'-methyl-4-(dimethylamino)azobenzene-induced rat hepatocellular carcinomas. ( Kitagawa, T; Lee, GH; Li, H; Liu, J; Nomura, K; Ohtake, K, 1991) |
| "Activation of ras protooncogenes in 11 2-acetylaminofluorene (AAF)-induced hepatocellular carcinomas (HCCs) or liver cell lines and 9 3'-methyl-(dimethylamino)azobenzene (3'-Me-DAB)-induced HCCs in rats was examined using the NIH3T3 cell transfection assay and oligonucleotide hybridization analysis." | 3.68 | Low frequency of ras activation in 2-acetylaminofluorene- and 3'-methyl-4-(dimethylamino)azobenzene-induced rat hepatocellular carcinomas. ( Kitagawa, T; Lee, GH; Li, H; Liu, J; Nomura, K; Ohtake, K, 1991) |
| " Examples are shown, illustrating that the current practice of labeling dose-response curves for carcinogenesis as supralinear, linear or sublinear, is meaningless unless the dose-response scales are defined." | 2.43 | Critique of dose response in carcinogenesis. ( Waddell, WJ, 2006) |
| "HMGB3 in human liver cancer tissues were evaluated using bioinformatics databases from GEO, TCGA, and Oncomine." | 1.48 | Abnormal expression of ( Dong, ZZ; Fang, M; Wang, L; Yao, DF; Yao, M; Zheng, WJ, 2018) |
| " The rats were observed daily and body weights were taken before initial dosing and at weekly intervals thereafter." | 1.34 | Inhibition by dietary hydroquinone of acetylaminofluorene induction of initiation of rat liver carcinogenesis. ( Duan, JD; Iatropoulos, MJ; Jeffrey, AM; Williams, GM, 2007) |
| "Acetaminophen was given in the diet either alone at 2400 or 4800 p." | 1.34 | Inhibition by acetaminophen of neoplastic initiation elicited in rat liver by the DNA-reactive hepatocarcinogen N-acetyl-2-aminofluorene. ( Duan, JD; Iatropoulos, MJ; Jeffrey, AM; Perrone, CE; Williams, GM, 2007) |
| "With phenobarbital treatment the total focal volume was 20% of the liver volume three weeks after PH, whereas the corresponding value in the case of 3-methylcholanthrene was only 1%." | 1.30 | Induced drug resistance inhibits selection of initiated cells and cancer development. ( Eriksson, LC; Rissler, P; Torndal, UB, 1997) |
| " Moreover, maximal mutation frequency at the Na+/K(+)-ATPase gene locus (ouar mutation) was attained within 30 or 40 min of exposure, dependent on dosage of N-NO-AAF." | 1.28 | Induction of ouabain-resistance mutation and cycle-dependent transformation of C3H/10T1/2 cells by N-nitroso-2-acetylaminofluorene. ( Kuo, ML; Lin, JK, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (60.56) | 18.7374 |
| 1990's | 11 (15.49) | 18.2507 |
| 2000's | 9 (12.68) | 29.6817 |
| 2010's | 8 (11.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, WJ | 1 |
| Yao, M | 4 |
| Fang, M | 1 |
| Wang, L | 2 |
| Dong, ZZ | 2 |
| Yao, DF | 6 |
| Matboli, M | 1 |
| ElGwad, AA | 1 |
| Hasanin, AH | 1 |
| El-Tawdi, A | 1 |
| Habib, EK | 1 |
| Elmansy, RA | 1 |
| Ibrahim, D | 1 |
| Shehata, H | 1 |
| Tash, F | 1 |
| Papp, V | 1 |
| Rókusz, A | 1 |
| Dezső, K | 1 |
| Bugyik, E | 1 |
| Szabó, V | 1 |
| Pávai, Z | 1 |
| Paku, S | 1 |
| Nagy, P | 2 |
| Yan, XD | 1 |
| Zhang, HJ | 2 |
| Yan, MJ | 1 |
| Gu, X | 1 |
| Shi, Y | 1 |
| Chen, J | 1 |
| Qiu, LW | 4 |
| Zong, L | 1 |
| Lu, YY | 1 |
| Huang, H | 1 |
| Wu, W | 4 |
| Wu, XH | 3 |
| Jiang, H | 1 |
| Li, YM | 2 |
| Gu, WJ | 2 |
| Shen, YC | 1 |
| Sai, WL | 3 |
| Shen, JJ | 1 |
| Yu, HB | 1 |
| Wang, YL | 1 |
| Alwahaibi, NY | 1 |
| Budin, SB | 1 |
| Mohamed, J | 1 |
| Alhamdani, A | 1 |
| Rohrbeck, A | 1 |
| Salinas, G | 1 |
| Maaser, K | 1 |
| Linge, J | 1 |
| Salovaara, S | 1 |
| Corvi, R | 1 |
| Borlak, J | 1 |
| Bian, YZ | 1 |
| Zhang, CG | 1 |
| Yang, JL | 1 |
| Satoh, K | 1 |
| Yamakawa, D | 1 |
| Kasai, K | 1 |
| Hayakari, M | 1 |
| Uchida, K | 1 |
| Miura, T | 1 |
| Amin, I | 1 |
| Koh, BK | 1 |
| Asmah, R | 1 |
| Groos, J | 1 |
| Kopp-Schneider, A | 1 |
| Waddell, WJ | 1 |
| Carrasco-Legleu, CE | 1 |
| Sánchez-Pérez, Y | 1 |
| Márquez-Rosado, L | 1 |
| Fattel-Fazenda, S | 1 |
| Arce-Popoca, E | 1 |
| Hernández-García, S | 1 |
| Villa-Treviño, S | 1 |
| Williams, GM | 7 |
| Iatropoulos, MJ | 2 |
| Jeffrey, AM | 2 |
| Duan, JD | 2 |
| Perrone, CE | 1 |
| Bibbiani, C | 1 |
| Malvaldi, G | 1 |
| Lebherz, WB | 1 |
| Shaikh, B | 1 |
| Pienta, RJ | 1 |
| Takahashi, S | 1 |
| Lombardi, B | 1 |
| Shinozuka, H | 1 |
| Becker, FF | 2 |
| Pickett, CB | 1 |
| Williams, JB | 1 |
| Lu, AY | 1 |
| Cameron, RG | 1 |
| Poiley, JA | 2 |
| Raineri, R | 2 |
| Katayama, S | 1 |
| Ohmori, T | 1 |
| Maeura, Y | 1 |
| Croci, T | 1 |
| Ernst, MK | 1 |
| Cavanaugh, DM | 1 |
| Sell, S | 3 |
| Salman, J | 1 |
| Creek, KE | 1 |
| Walter, VP | 1 |
| Evers, D | 1 |
| Yeo, E | 1 |
| Elliott, WL | 1 |
| Heinstein, PF | 1 |
| Morré, DM | 1 |
| Morré, DJ | 1 |
| Oshiro, Y | 1 |
| Balwierz, PS | 1 |
| Zimmerman, RJ | 2 |
| Little, JB | 2 |
| Farber, E | 2 |
| Ashby, J | 1 |
| Styles, JA | 1 |
| Lindahl, R | 1 |
| Evces, S | 1 |
| Sheng, WL | 1 |
| Oglesby, LA | 1 |
| Cudak, C | 1 |
| Curtis, G | 1 |
| Garland, H | 1 |
| Hyatt, B | 1 |
| Montgomery, L | 1 |
| Nesnow, S | 1 |
| Smith, BD | 1 |
| Niles, R | 1 |
| Teeter, LD | 1 |
| Estes, M | 1 |
| Chan, JY | 1 |
| Atassi, H | 1 |
| Kuo, MT | 1 |
| Umemura, T | 1 |
| Tokumo, K | 1 |
| Sirma, H | 1 |
| Gebhardt, R | 1 |
| Poirier, MC | 1 |
| Höhne, MW | 1 |
| Zieroth, S | 1 |
| Veser, U | 1 |
| Kahl, GF | 1 |
| Schwarz, LR | 1 |
| Rissler, P | 1 |
| Torndal, UB | 1 |
| Eriksson, LC | 1 |
| De Miglio, MR | 1 |
| Simile, MM | 1 |
| Muroni, MR | 1 |
| Pusceddu, S | 1 |
| Calvisi, D | 1 |
| Carru, A | 1 |
| Seddaiu, MA | 1 |
| Daino, L | 1 |
| Deiana, L | 1 |
| Pascale, RM | 1 |
| Feo, F | 1 |
| Bitsch, A | 1 |
| Klöhn, PC | 1 |
| Hadjiolov, N | 1 |
| Bergmann, O | 1 |
| Neumann, HG | 1 |
| Daniel, MR | 1 |
| Dehnel, JM | 1 |
| Elejalde, BR | 1 |
| Rubenchik, BL | 1 |
| Romanenko, AM | 1 |
| Landolph, JR | 1 |
| Heidelberger, C | 1 |
| Miller, EC | 1 |
| Anichkov, NM | 1 |
| Tonelli, QJ | 1 |
| Custer, RP | 1 |
| Sorof, S | 1 |
| Parker, S | 1 |
| Gruenstein, M | 1 |
| Weinstein, IB | 1 |
| Kitagawa, T | 3 |
| Ball, WJ | 1 |
| Salser, JS | 1 |
| Balis, ME | 1 |
| Li, H | 1 |
| Lee, GH | 1 |
| Liu, J | 1 |
| Nomura, K | 1 |
| Ohtake, K | 1 |
| Maruyama, H | 1 |
| Tanaka, T | 1 |
| Lin, JK | 1 |
| Kuo, ML | 1 |
| Gerlyng, P | 1 |
| Seglen, PO | 2 |
| Evarts, RP | 1 |
| Nakatsukasa, H | 1 |
| Marsden, E | 1 |
| Thorgeirsson, SS | 2 |
| Embleton, MJ | 1 |
| James, HS | 1 |
| Haynes, AJ | 1 |
| Butler, PC | 1 |
| Schwarze, PE | 1 |
| Schechtman, LM | 1 |
| Hatch, GG | 1 |
| Anderson, TM | 1 |
| Putman, DL | 1 |
| Kouri, RE | 1 |
| Cameron, JW | 1 |
| Nims, RW | 1 |
| Spalding, JW | 1 |
| Tennant, RW | 1 |
| Lubet, RA | 1 |
| Kessler, DJ | 1 |
| Heilman, CA | 1 |
| Cossman, J | 1 |
| Maguire, RT | 1 |
| Shirai, T | 1 |
| Tsuda, H | 1 |
| Ogiso, T | 1 |
| Hirose, M | 1 |
| Ito, N | 1 |
| Préat, V | 1 |
| de Gerlache, J | 2 |
| Lans, M | 2 |
| Roberfroid, M | 1 |
| Sivak, A | 1 |
| Tu, AS | 1 |
| Peraino, C | 1 |
| Vesselinovitch, SD | 1 |
| Novicki, DL | 1 |
| Rosenberg, MR | 1 |
| Michalopoulos, G | 1 |
| Sugioka, Y | 1 |
| Fujii-Kuriyama, Y | 1 |
| Muramatsu, M | 1 |
| Deleener, A | 1 |
| Kirsch-Volders, M | 1 |
7 reviews available for 2-acetylaminofluorene and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Critique of dose response in carcinogenesis.
Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Carcinogenicity Tests; Carcinogens; Cell Transformation, | 2006 |
The sequential analysis of liver cancer induction.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Female; | 1980 |
Carcinogenic synergism and its reflection in vitro.
Topics: 2-Acetylaminofluorene; Acetanilides; Aminobiphenyl Compounds; Animals; Azo Compounds; Carcinogens; C | 1980 |
Some current perspectives on chemical carcinogenesis in humans and experimental animals: Presidential Address.
Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Biotransformation; Carcinogens; Carcinogens, Environment | 1978 |
[Experimental replication of bladder tumors. Morphologic features of early stages of their development].
Topics: 2-Acetylaminofluorene; 2-Naphthylamine; Animals; Butylhydroxybutylnitrosamine; Cell Membrane; Cell T | 1979 |
Cellular effects of chemical carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Butylated Hydroxytoluene; Carcinogens; Cell Transformation, Neoplast | 1986 |
Single-hit versus multi-hit concept of hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Age Factors; Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylni | 1985 |
64 other studies available for 2-acetylaminofluorene and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Abnormal expression of
Topics: 2-Acetylaminofluorene; Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepatocellular; | 2018 |
Pantoprazole attenuates tumorigenesis via inhibition of exosomal secretion in a rat model of hepatic precancerous lesion induced by diethylnitrosamine and 2-acetamidofluorene.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diethyln | 2019 |
Expansion of hepatic stem cell compartment boosts liver regeneration.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Different | 2014 |
Overexpression of insulin-like growth factor-I receptor as a pertinent biomarker for hepatocytes malignant transformation.
Topics: 2-Acetylaminofluorene; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Transformation, N | 2013 |
Abnormal expression of insulin-like growth factor-II and its dynamic quantitative analysis at different stages of hepatocellular carcinoma development.
Topics: 2-Acetylaminofluorene; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Transformation, N | 2008 |
Quantitative analysis of hepatic hypoxia-inducible factor-1alpha and its abnormal gene expression during the formation of hepatocellular carcinoma.
Topics: 2-Acetylaminofluorene; Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Transformation, Neopl | 2009 |
Characteristics of hepatic nuclear-transcription factor-kappa B expression and quantitative analysis in rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Transformation, N | 2009 |
Nuclear factor-kappa B as a promising target for selenium chemoprevention in rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cyclin D1; | 2010 |
Toxicogenomics applied to in vitro carcinogenicity testing with Balb/c 3T3 cells revealed a gene signature predictive of chemical carcinogens.
Topics: 2-Acetylaminofluorene; Animals; BALB 3T3 Cells; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; | 2010 |
Oncofetal antigen glypican-3 as a promising early diagnostic marker for hepatocellular carcinoma.
Topics: 2-Acetylaminofluorene; Animals; Biomarkers, Tumor; Blotting, Western; Carcinoma, Hepatocellular; Cel | 2011 |
Nonclonal growth of preneoplastic cells positive for glutathione S-transferase P-form in the rat liver.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Glutathione Transferase; Hepatocyte | 2012 |
Effect of cacao liquor extract on tumor marker enzymes during chemical hepatocarcinogenesis in rats.
Topics: 2-Acetylaminofluorene; Alkaline Phosphatase; Analysis of Variance; Animals; Biomarkers, Tumor; Cacao | 2004 |
Application of a color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Neoplastic; Glutathione S-Transfer | 2006 |
A single dose of caffeic acid phenethyl ester prevents initiation in a medium-term rat hepatocarcinogenesis model.
Topics: 2-Acetylaminofluorene; Animals; Caffeic Acids; Carcinogens; Cell Proliferation; Cell Transformation, | 2006 |
Inhibition by dietary hydroquinone of acetylaminofluorene induction of initiation of rat liver carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Antioxidants; Carcinogens; Cell Division; Cell Transformation, Neopl | 2007 |
Inhibition by acetaminophen of neoplastic initiation elicited in rat liver by the DNA-reactive hepatocarcinogen N-acetyl-2-aminofluorene.
Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Antineoplastic Agents; Body Weight; Carcinoma, Hepato | 2007 |
[Induction, characterization and isolation of preneoplastic hepatocytes following combined treatment with 2-acetaminofluorene and ferric nitrilotriacetate].
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Centrifugation, Isopycnic; Ferric C | 1981 |
Detection of urinary metabolites of 2-acetylaminofluorene by cultured hamster embryo cells and high performance liquid chromatography.
Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Cell Transformation, Neoplastic; Cells, Cultured; | 1980 |
Progression of carcinogen-induced foci of gamma-glutamyltranspeptidase-positive hepatocytes to hepatomas in rats fed a choline-deficient diet.
Topics: 2-Acetylaminofluorene; Animal Feed; Animals; Cell Transformation, Neoplastic; Choline Deficiency; Di | 1982 |
The direct and indirect effects of promoters may depend upon the nature of the initiated cell.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; DN | 1983 |
Regulation of glutathione transferase and DT-diaphorase mRNAs in persistent hepatocyte nodules during chemical hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; DNA; Glutathione Transferase; Liver | 1984 |
Species specificity affects the choice of S9 preparations for use in the hamster embryo cell transformation system.
Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Cell Transformation, Neoplastic; Cricetinae; Inte | 1984 |
Early stages of N-2-fluorenylacetamide-induced hepatocarcinogenesis in male and female rats and effect of gonadectomy on liver neoplastic conversion and neoplastic development.
Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Castration; Cell Transformation, Neop | 1984 |
Use of the hamster embryo cell transformation assay to detect metabolic activation of N-2-acetylaminofluorene by intact organ cells.
Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Cell Transformation, Neoplastic; Cricetinae; Embr | 1983 |
Light- and electron-microscopic autoradiographic analysis of proliferating cells during the early stages of chemical hepatocarcinogenesis in the rat induced by feeding N-2-fluorenylacetamide in a choline-deficient diet.
Topics: 2-Acetylaminofluorene; Animals; Autoradiography; Cell Transformation, Neoplastic; Choline Deficiency | 1984 |
Sialoglycoconjugate changes during 2-acetylaminofluorene-induced hepatocarcinogenesis in the rat.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Cytidine Monophosphate N-Acetylneur | 1984 |
Morphological transformation of C3H/10T1/2 CL8 cells by procarcinogens.
Topics: 2-Acetylaminofluorene; 2-Naphthylamine; 4-Nitroquinoline-1-oxide; Aflatoxin B1; Aflatoxins; Animals; | 1982 |
Characteristics of human diploid fibroblasts transformed in vitro by chemical carcinogens.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Calcium; Cell Division; Cell Transformat | 1983 |
Expression of the tumor aldehyde dehydrogenase phenotype during 2-acetylaminofluorene-induced rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Cell Transformatio | 1982 |
Relationship of N-arylacetamide metabolism and macromolecular binding to oncogenic transformation of C3H10T1/2CL8 cells.
Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Cell Line; Cell Transformation, Neoplastic; Mice; | 1982 |
Starvation for arginine and glutamine sensitizes human diploid cells to the transforming effects of N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Arginine; Cell Transformation, Neoplastic; Cells, | 1981 |
Characterization of collagen synthesized by normal and chemically transformed rat liver epithelial cell lines.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Cell Line; Cell Transformation, Neoplast | 1980 |
Activation of distinct multidrug-resistance (P-glycoprotein) genes during rat liver regeneration and hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequen | 1993 |
Dose response effects of 2-acetylaminofluorene on DNA damage, cytotoxicity, cell proliferation and neoplastic conversion in rat liver.
Topics: 2-Acetylaminofluorene; Animals; Cell Division; Cell Survival; Cell Transformation, Neoplastic; DNA D | 1993 |
Carcinogen-induced diploid hepatocytes: sensitive target cells for transformation by mutated c-Ha-ras oncogene.
Topics: 2-Acetylaminofluorene; Animals; Base Sequence; Cell Separation; Cell Transformation, Neoplastic; Die | 1993 |
Induced drug resistance inhibits selection of initiated cells and cancer development.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Neoplastic; Drug Resistance, Neopl | 1997 |
Correlation of c-myc overexpression and amplification with progression of preneoplastic liver lesions to malignancy in the poorly susceptible Wistar rat strain.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Cell Transformation, Neoplastic; Chloroform; Diethylnitro | 1999 |
New insights into carcinogenesis of the classical model arylamine 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Carcinogens; Cell Division; Cell Transformation, Neoplast | 1999 |
Factors affecting the performance of the styles cell transformation test.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Agar; Animals; Benzo(a)pyrene; Biotransformation; B | 1980 |
Functional markers and growth behavior of preneoplastic hepatocytes.
Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Cell Aggregation; Cell Transformation, Neoplasti | 1976 |
In-vitro transformation of cells from patients with naevoid basal-cell-carcinoma syndrome.
Topics: 2-Acetylaminofluorene; Adult; Carcinoma, Basal Cell; Cell Transformation, Neoplastic; Child; Humans; | 1976 |
[Hyperplastic foci in chemical carcinogenesis].
Topics: 2-Acetylaminofluorene; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Diethyln | 1976 |
Chemical carcinogens produce mutations to ouabain resistance in transformable C3H/10T1/2 Cl 8 mouse fibroblasts.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Dose- | 1979 |
Transformation of cultured mouse mammary glands by aromatic amines and amides and their derivatives.
Topics: 1-Naphthylamine; 2-Acetylaminofluorene; 2-Naphthylamine; Acetoxyacetylaminofluorene; Animals; Cell T | 1979 |
The resistance of putative premalignant liver cell populations, hyperplastic nodules, to the acute cytotoxic effects of some hepatocarcinogens.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Cell Transformation, Neoplastic; | 1976 |
Molecular and cellular mechanisms of chemical carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chemical Phenomena | 1976 |
Sequential phenotypic changes in hyperplastic areas during hepatocarcinogenesis in the rat.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Glucuronidase; Hyperplasia; L-Serin | 1976 |
Biochemical changes in preneoplastic rodent intestines.
Topics: 2-Acetylaminofluorene; Age Factors; Animals; Carboxy-Lyases; Cell Transformation, Neoplastic; Dimeth | 1976 |
Is there a liver stem cell?
Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Bile Ducts; Cell Differentiation; Cell Transform | 1990 |
Low frequency of ras activation in 2-acetylaminofluorene- and 3'-methyl-4-(dimethylamino)azobenzene-induced rat hepatocellular carcinomas.
Topics: 2-Acetylaminofluorene; Animals; Blotting, Southern; Carcinoma, Hepatocellular; Cell Transformation, | 1991 |
Effects of the peroxisome proliferator di(2-ethylhexyl)phthalate on enzymes in rat liver and on carcinogen-induced liver altered foci in comparison to the promoter phenobarbital.
Topics: 2-Acetylaminofluorene; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cell Transformation, N | 1990 |
Induction of ouabain-resistance mutation and cycle-dependent transformation of C3H/10T1/2 cells by N-nitroso-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cell Transforma | 1990 |
Effects of the tumor promoter 2-acetylaminofluorene and of 4-acetylaminofluorene on rat liver growth.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Liver; | 1990 |
In vivo differentiation of rat liver oval cells into hepatocytes.
Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Cell Transformation, Neoplastic; DNA; gamma-Glut | 1989 |
Heterogeneity of hepatocyte antigen expression in rat liver carcinogenesis: concordance between neoplastic nodules and tumours.
Topics: 2-Acetylaminofluorene; Animals; Antibodies, Monoclonal; Antigens; Cell Transformation, Neoplastic; I | 1989 |
Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats.
Topics: 2-Acetylaminofluorene; Adenine; Adenosine Triphosphatases; Amino Acids; Animals; Autophagy; Carcinog | 1985 |
Analysis of the interlaboratory and intralaboratory reproducibility of the enhancement of simian adenovirus SA7 transformation of Syrian hamster embryo cells by model carcinogenic and noncarcinogenic compounds.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Adenoviridae; Ade | 1986 |
Transformation of Epstein-Barr virus immortalized human B-cells by chemical carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Antigens, Neoplasm; Antigens, Surface; B-Lymphocytes; Cell Transform | 1987 |
Organ specific modifying potential of ethinyl estradiol on carcinogenesis initiated with different carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Interactio | 1987 |
Promoting effect of oxazepam in rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Diethylnitrosamin | 1987 |
Use of rodent hepatocytes for metabolic activation in transformation assays.
Topics: 2-Acetylaminofluorene; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cell Cycle; Cell L | 1985 |
Inhibition of DNA synthesis by chemical carcinogens in cultures of initiated and normal proliferating rat hepatocytes.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, | 1985 |
Changes in polypeptide pattern of rat liver cells during chemical hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Aging; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Liver; L | 1985 |
Nucleolar changes during the first steps of experimental hepatocarcinogenesis in rats.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Nucleolus; Cell Transformation, Neoplasti | 1985 |