2-acetylaminofluorene has been researched along with Carcinoma in 9 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The data indicate that at least in hepatocellular tumours of the C57Bl/10J strain and using chronic dosing regimes the ras genes do not represent markers for in vivo genotoxic activity." | 1.28 | Point mutation analysis of ras genes in spontaneous and chemically induced C57Bl/10J mouse liver tumours. ( Hardaker, KJ; Lord, PG; Loughlin, JM; Marsden, AM; Orton, TC, 1992) |
| " Hence, the levels of statistical significance obtained for dose-response trends and comparisons of treated and control groups were similar using 48 animals per dose groups with B6C3 mice, or combinations of 24 animals per dose from 2 genotypes, or 12 animals per dose from the 4 hybrid genotypes." | 1.28 | Bladder and liver tumorigenesis induced by 2-acetylaminofluorene in different F1 mouse hybrids: variation within genotypes and effects of using more than one genotype on risk assessment. ( Blackwell, BN; Gaylor, DW; Moore, GE; Wolff, GL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SKORYNA, SC | 1 |
| ROSS, RC | 1 |
| RUDIS, LA | 1 |
| Williams, GM | 1 |
| Maeura, Y | 1 |
| Weisburger, JH | 1 |
| Jull, JW | 1 |
| Matsumoto, M | 1 |
| Hopp, ML | 1 |
| Oyasu, R | 1 |
| Reuber, MD | 2 |
| Lord, PG | 1 |
| Hardaker, KJ | 1 |
| Loughlin, JM | 1 |
| Marsden, AM | 1 |
| Orton, TC | 1 |
| Wolff, GL | 1 |
| Gaylor, DW | 1 |
| Blackwell, BN | 1 |
| Moore, GE | 1 |
| Poirier, MC | 1 |
| Fullerton, NF | 1 |
| Kinouchi, T | 1 |
| Smith, BA | 1 |
| Beland, FA | 1 |
9 other studies available for 2-acetylaminofluorene and Carcinoma
| Article | Year |
|---|---|
Histogenesis of sebaceous gland carcinomas produced in rats by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma; Rats; Sebaceous Glands | 1951 |
Simultaneous inhibition of liver carcinogenicity and enhancement of bladder carcinogenicity of N-2-fluorenylacetamide by butylated hydroxytoluene.
Topics: 2-Acetylaminofluorene; Animals; Butylated Hydroxytoluene; Carcinoma; Carcinoma, Hepatocellular; Coca | 1983 |
The effect of time on the incidence of carcinomas obtained by the implantation of paraffin wax pellets into mouse bladder.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma; Female; Mice; Naphthols; Neoplasms, Experimental; Paraffi | 1979 |
Effect of pair-feeding of carcinogen on the incidence of bladder tumors in hamsters. Role of indole, age, and sex.
Topics: 2-Acetylaminofluorene; Administration, Oral; Age Factors; Animals; Carcinoma; Cricetinae; Diet; Fema | 1976 |
Carcinoma and cirrhosis of the liver in A X C male rats with one kidney ingesting 0.025% N-2-fluorenyldiacetamide.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma; Carcinosarcoma; Diet; Fluorenes; Kidney; Liver Cirrhosis, | 1975 |
Decreased incidence of renal cell carcinoma in rats with one kidney ingesting N-4-(4'-fluorobiphenyl)acetamide.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Carcinoma; Kidney Neoplasms; Liver Neoplasms; Male; Nep | 1976 |
Point mutation analysis of ras genes in spontaneous and chemically induced C57Bl/10J mouse liver tumours.
Topics: 2-Acetylaminofluorene; Adenoma; Aminobiphenyl Compounds; Animals; Base Sequence; Carcinoma; Diethyln | 1992 |
Bladder and liver tumorigenesis induced by 2-acetylaminofluorene in different F1 mouse hybrids: variation within genotypes and effects of using more than one genotype on risk assessment.
Topics: 2-Acetylaminofluorene; Animals; Carcinoma; Female; Genotype; Liver Neoplasms, Experimental; Male; Mi | 1991 |
Comparison between DNA adduct formation and tumorigenesis in livers and bladders of mice chronically fed 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Adenoma; Animals; Autoradiography; Carcinoma; Chromatography, High Pressure L | 1991 |