2-acetylaminofluorene has been researched along with Carcinogenesis in 25 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using the Solt and Farber protocol in a rat model of hepatocarcinogenesis, the chemopreventive effect of EPM on diethylnitrosamine (DEN)-initiated, 2-acetylaminofluorene (2-AAF) and partial hepatectomy (PH)-promoted liver carcinogenesis in rats was evaluated." | 7.85 | Ethanol extract of Phellinus merrillii protects against diethylnitrosamine- and 2-acetylaminofluorene-induced hepatocarcinogenesis in rats. ( Chang, HY; Chen, YC; Huang, GJ; Huang, SS; Lai, HC; Lu, CC; Yang, CH, 2017) |
| " Using the Solt and Farber protocol in a rat model of hepatocarcinogenesis, the chemopreventive effect of EPM on diethylnitrosamine (DEN)-initiated, 2-acetylaminofluorene (2-AAF) and partial hepatectomy (PH)-promoted liver carcinogenesis in rats was evaluated." | 3.85 | Ethanol extract of Phellinus merrillii protects against diethylnitrosamine- and 2-acetylaminofluorene-induced hepatocarcinogenesis in rats. ( Chang, HY; Chen, YC; Huang, GJ; Huang, SS; Lai, HC; Lu, CC; Yang, CH, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (76.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (20.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bose, P | 1 |
| Siddique, MUM | 1 |
| Acharya, R | 1 |
| Jayaprakash, V | 1 |
| Sinha, BN | 1 |
| Lapenna, A | 1 |
| Pattanayak, SP | 1 |
| Thomas, NS | 1 |
| George, K | 1 |
| Selvam, AAA | 1 |
| Kindrat, I | 1 |
| Tryndyak, V | 1 |
| de Conti, A | 1 |
| Shpyleva, S | 1 |
| Mudalige, TK | 1 |
| Kobets, T | 1 |
| Erstenyuk, AM | 1 |
| Beland, FA | 1 |
| Pogribny, IP | 1 |
| Yang, CH | 1 |
| Chang, HY | 1 |
| Chen, YC | 1 |
| Lu, CC | 1 |
| Huang, SS | 1 |
| Huang, GJ | 1 |
| Lai, HC | 1 |
| Gu, JJ | 1 |
| Yao, M | 1 |
| Yang, J | 1 |
| Cai, Y | 1 |
| Zheng, WJ | 1 |
| Wang, L | 1 |
| Yao, DB | 1 |
| Yao, DF | 1 |
| Malik, S | 1 |
| Bhatnagar, S | 1 |
| Chaudhary, N | 1 |
| Katare, DP | 1 |
| Jain, SK | 1 |
| RUTMAN, RJ | 3 |
| CANTAROW, A | 3 |
| PASCHKIS, KE | 3 |
| MORI, K | 1 |
| ICHII, S | 1 |
| NAGASE, K | 1 |
| PIROZYNSKI, WJ | 1 |
| VON BERTALANFFY, L | 1 |
| SCHINZ, HR | 1 |
| KORPASSY, B | 2 |
| MOSONYI, M | 2 |
| SZTANOJEVITS, A | 2 |
| TRAUB, A | 2 |
| MILLER, EC | 2 |
| MILLER, JA | 2 |
| BROWN, RR | 1 |
| MACDONALD, JC | 1 |
| NICHOLSON, ML | 1 |
| BURKE, WT | 1 |
| MILLER, LL | 1 |
| CRAMER, JW | 1 |
| SCHRAMM, T | 1 |
| SIDRANSKY, H | 1 |
| CLARK, S | 1 |
| BABA, T | 1 |
| WEISBURGER, JH | 1 |
| WEISBURGER, EK | 1 |
| RITCHIE, AC | 1 |
| SAFFIOTTI, U | 1 |
| REES, KR | 1 |
| ROWLAND, GF | 1 |
| ROSS, HF | 1 |
| BIELSCHOWSKY, F | 1 |
| HALL, WH | 1 |
| GRIFFIN, AC | 1 |
| COOK, H | 1 |
| CUNNINGHAM, L | 1 |
25 other studies available for 2-acetylaminofluorene and Carcinogenesis
| Article | Year |
|---|---|
Quinazolinone derivative BNUA-3 ameliorated [NDEA+2-AAF]-induced liver carcinogenesis in SD rats by modulating AhR-CYP1B1-Nrf2-Keap1 pathway.
Topics: 2-Acetylaminofluorene; Animals; Antineoplastic Agents; Antioxidants; Carcinogenesis; Carcinogens; Cy | 2020 |
Troxerutin subdues hepatic tumorigenesis via disrupting the MDM2-p53 interaction.
Topics: 2-Acetylaminofluorene; Animals; Antineoplastic Agents; Apoptosis; Carcinogenesis; Disease Progressio | 2018 |
MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Antigens, CD; Blotting, Western; Carcinogenesis; Carcinogens; Carcin | 2016 |
Ethanol extract of Phellinus merrillii protects against diethylnitrosamine- and 2-acetylaminofluorene-induced hepatocarcinogenesis in rats.
Topics: 2-Acetylaminofluorene; Animals; Basidiomycota; Carcinogenesis; Cytoprotection; Diethylnitrosamine; E | 2017 |
Mitochondrial carnitine palmitoyl transferase-II inactivity aggravates lipid accumulation in rat hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinogenesis; C | 2017 |
DEN+2-AAF-induced multistep hepatotumorigenesis in Wistar rats: supportive evidence and insights.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Diethylnitrosamine; Disease Models, Animal; Lipid Pe | 2013 |
Studies in 2-acetylaminofluorene carcinogenesis. I. The intracellular distribution of nucleic acids and protein in rat liver.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Fluorenes; Liver; Neoplasms; Neoplasms, Experimental | 1954 |
Studies in 2-acetylaminofluorene carcinogenesis. II. The in vitro uptake of alanine-1-C14 by preneoplastic liver and hepatoma mitochondrial protein.
Topics: 2-Acetylaminofluorene; Alanine; Carcinogenesis; Carcinoma, Hepatocellular; Fluorenes; In Vitro Techn | 1954 |
Studies in 2-acetylaminofluorene carcinogenesis. III. The utilization of uracil-2-C14 by preneoplastic rat liver and rat hepatoma.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Fluorenes; Liver Neoplasm | 1954 |
Catalase and uricase studies on rats during 2-acetylaminofluorene carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Catalase; En | 1954 |
Changes of cytoplasmic basophilia during carcinogenesis induced by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Basophils; Carcinogenesis; Fluorenes; Neoplasms, Experimental | 1955 |
[Zürich experiments with carcinogenesis by acetylaminofluorenes and certain derivatives].
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Diethylstilbestrol; Fluorenes; Neoplasms, Experiment | 1955 |
Chronic local irritation and acetylaminofluorene carcinogenesis.
Topics: 2-Acetylaminofluorene; Carcinogenesis; Fluoresceins; Humans; Stomach Neoplasms; Tannins | 1955 |
[Chronic local irritations and acetylaminofluorene carcinogenesis].
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Carcinogens; Fluoresceins; Neoplasms, Experimental | 1956 |
On the protective action of certain polycyclic aromatic hydrocarbons against carcinogenesis by aminoazo dyes and 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Carcinogenesis; Carcinogens; Coloring Agents; Fluorenes; Humans; Hydrocarbons | 1958 |
[Carcinogenesis after feeding 2-acetylaminofluorene to rats with simultaneous 31 Me V irradiation & vitamin B12 treatment].
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Fluorenes; Gamma Rays; Neoplasms, Experimental; Rats | 1958 |
Biochemical changes during carcinogenesis. IV. Protein synthesis and urea production in perfused livers of rats fed 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Carcinogens; Liver; Protein Biosynthesis; Proteins; | 1960 |
The N- and ringhydroxylation of 2-acetylaminofluorene during carcinogenesis in the rat.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Neoplasms, Experimental; Rats | 1960 |
[The effect of fatty acids on carcinogenesis. III. The effect of linolenic acid ethyl ester on 2-acetylaminofluorene induced carcinogenesis].
Topics: 2-Acetylaminofluorene; Animals; Arachidonic Acid; Carcinogenesis; Fatty Acids; Fluorenes; Linolenic | 1961 |
Influence of p-hydroxy-propiophenone on liver tumorigenesis in rats ingesting ethionine and N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Carcinogens; Ethionine; Fluorenes; Hydroxypropiophen | 1963 |
ENDOGENOUS AND EXOGENOUS FACTORS IN CHEMICAL CARCINOGENESIS BY N-2-FLUORENYLACETAMIDE.
Topics: 2-Acetylaminofluorene; Carbon Isotopes; Carcinogenesis; Fluorenes; Liver Neoplasms; Metabolism; Neop | 1963 |
Orally administered 2-acetylaminofluorene as an initiator and as a promoter in epidermal carcinogenesis in the mouse.
Topics: 2-Acetylaminofluorene; Animals; Benz(a)Anthracenes; Carcinogenesis; Croton Oil; Fluorenes; Mice; Neo | 1955 |
The metabolism of isolated rat-liver nuclei during chemical carcinogenesis. 2. 2-Acetamidofluorene, alpha-naphthyl isothiocyanate and 2', 4'-dimethyl-4-dimethylaminoazobenzene.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Carcinogens; Fluorenes; Isothiocyanates; Liver; p-Di | 1962 |
Carcinogenesis in parabiotic rats; tumours of liver and seminal vesicle induced by acetylaminofluorene in normal males joined to castrated males or females.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenesis; Female; Humans; Liver Neoplasms; Male; Neoplasms; Ra | 1951 |
Tissue proteins and carcinogenesis; precancerous changes in the liver and serum proteins of rats fed acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Blood Proteins; Carcinogenesis; Fluorenes; Liver; Neoplasms; Rats | 1949 |