2-acetylaminofluorene has been researched along with Cancer of the Thyroid in 6 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous chronic administration of chlorpromazine (CPZ) before the start of the 2-acetylaminofluorene (2-AAF) action and during the cancerogenic process systematically facilitate the growth of apudome-like medullary tumors inside the thyroid gland." | 5.27 | [The C cell system and experimental thyroid apudomas in the rat: the combined action of 2-acetylaminofluorene and chlorpromazine in inducing systemic medullary type tumors. An ultrastructural study]. ( Alliet, J; Lalégerie, P; Théret, CG, 1984) |
| "Previous chronic administration of chlorpromazine (CPZ) before the start of the 2-acetylaminofluorene (2-AAF) action and during the cancerogenic process systematically facilitate the growth of apudome-like medullary tumors inside the thyroid gland." | 1.27 | [The C cell system and experimental thyroid apudomas in the rat: the combined action of 2-acetylaminofluorene and chlorpromazine in inducing systemic medullary type tumors. An ultrastructural study]. ( Alliet, J; Lalégerie, P; Théret, CG, 1984) |
| "025% 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) for two weeks combined with partial hepatectomy at the end of the first week and followed by long-term treatment with phenobarbital (PB) or 3'-methyl-4-dimethylaminoazobenzene (3'-Me-DAB) from week 3 to week 86 resulted in dose-dependent development of liver and thyroid neoplastic and preneoplastic lesions." | 1.27 | Dose-dependent induction of liver and thyroid neoplastic lesions by short-term administration of 2-amino-3-methylimidazo[4,5-f]quinoline combined with partial hepatectomy followed by phenobarbital or low dose 3'-methyl-4-dimethylaminoazobenzene promotion. ( Asamoto, M; Inoue, T; Ito, N; Nagao, M; Ogiso, T; Tsuda, H, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HALL, WH | 1 |
| Théret, CG | 1 |
| Alliet, J | 1 |
| Lalégerie, P | 1 |
| Hagiwara, A | 1 |
| Tanaka, H | 1 |
| Imaida, K | 2 |
| Tamano, S | 1 |
| Fukushima, S | 1 |
| Ito, N | 4 |
| Tsuda, H | 3 |
| Asamoto, M | 1 |
| Ogiso, T | 3 |
| Inoue, T | 1 |
| Nagao, M | 1 |
| Hasegawa, R | 1 |
| Masui, T | 1 |
| Shirai, T | 1 |
| Hirose, M | 1 |
6 other studies available for 2-acetylaminofluorene and Cancer of the Thyroid
| Article | Year |
|---|---|
The role of initiating and promoting factors in the pathogenesis of tumors of the thyroid.
Topics: 2-Acetylaminofluorene; Animals; Neoplasms; Rats; Thyroid Gland; Thyroid Neoplasms | 1948 |
[The C cell system and experimental thyroid apudomas in the rat: the combined action of 2-acetylaminofluorene and chlorpromazine in inducing systemic medullary type tumors. An ultrastructural study].
Topics: 2-Acetylaminofluorene; Animals; Apudoma; Chlorpromazine; Cocarcinogenesis; Golgi Apparatus; Microsco | 1984 |
Correlation between medium-term multi-organ carcinogenesis bioassay data and long-term observation results in rats.
Topics: 2-Acetylaminofluorene; Animals; Body Weight; Butylated Hydroxyanisole; Carcinogenicity Tests; Carcin | 1993 |
Dose-dependent induction of liver and thyroid neoplastic lesions by short-term administration of 2-amino-3-methylimidazo[4,5-f]quinoline combined with partial hepatectomy followed by phenobarbital or low dose 3'-methyl-4-dimethylaminoazobenzene promotion.
Topics: 2-Acetylaminofluorene; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Hepatectomy; Liv | 1988 |
Inhibition of neoplastic development in rat liver, kidney, oesophagus and forestomach by 4,4'-diaminodiphenylmethane administration.
Topics: 2-Acetylaminofluorene; Aniline Compounds; Animals; Esophageal Neoplasms; Kidney Neoplasms; Liver Neo | 1987 |
Organ specific modifying potential of ethinyl estradiol on carcinogenesis initiated with different carcinogens.
Topics: 2-Acetylaminofluorene; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Interactio | 1987 |