2-acetylaminofluorene has been researched along with Cancer, Radiation-Induced in 4 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoogervorst, EM | 1 |
| Bruins, W | 1 |
| Zwart, E | 1 |
| van Oostrom, CT | 1 |
| van den Aardweg, GJ | 1 |
| Beems, RB | 1 |
| van den Berg, J | 1 |
| Jacks, T | 1 |
| van Steeg, H | 2 |
| de Vries, A | 1 |
| Mullenders, LH | 1 |
| Vijg, J | 1 |
| Witcofski, RL | 1 |
| Pizzarello, DJ | 1 |
| Mori, H | 1 |
| Iwata, H | 1 |
| Morishita, Y | 1 |
| Mori, Y | 1 |
| Ohno, T | 1 |
| Tanaka, T | 1 |
| Sasaki, S | 1 |
4 other studies available for 2-acetylaminofluorene and Cancer, Radiation-Induced
| Article | Year |
|---|---|
Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; DNA Damage; Female; Genes, p53; Lymphoma; Male; Mice; M | 2005 |
Mutagenesis and carcinogenesis in nucleotide excision repair-deficient XPA knock out mice.
Topics: 2-Acetylaminofluorene; Animals; Base Sequence; Benzo(a)pyrene; Cocarcinogenesis; DNA Repair; DNA-Bin | 2000 |
Influence of dose rate on carcinogenesis resulting from x-ray, 113In, and 198Au irradiation.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Gold Radioisotopes; Indium; Isotopes; Liver; Liver Neop | 1976 |
Synergistic effect of radiation on N-2-fluorenylacetamide-induced hepatocarcinogenesis in male ACI/N rats.
Topics: 2-Acetylaminofluorene; Animals; Drug Synergism; Liver; Liver Neoplasms, Experimental; Male; Neoplasm | 1990 |