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2-acetylaminofluorene and Body Weight

2-acetylaminofluorene has been researched along with Body Weight in 60 studies

2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" Two diets used widely in toxicological and/or nutritional studies, and considered to be nutritionally adequate, were compared with respect to their influence on growth, body weight, lifespan, spontaneous neoplasia, and neoplastic responses to 2-acetylaminofluorene (2-AAF)."3.68Effects of diet type on incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors in BALB/c mice fed AIN-76A diet versus NIH-07 diet. ( Bucci, TJ; Fullerton, FR; Greenman, DL, 1992)
" Rats were initially given a single ip injection of diethylnitrosamine (200 mg/kg body weight) and fed basal diet containing 0."3.67Inhibitory effects of ethoxyquin, 4,4'-diaminodiphenylmethane and acetaminophen on rat hepatocarcinogenesis. ( Inoue, K; Ito, N; Masui, T; Ogiso, T; Tsuda, H, 1986)
" In contrast, the liver neoplasm promoter phenobarbital increased the multiplicity, although not the incidence, of liver neoplasms when given after FAA."3.67Absence of a promoting or sequential syncarcinogenic effect in rat liver by the carcinogenic hypolipidemic drug nafenopin given after N-2-fluorenylacetamide. ( Furuya, K; Levine, WG; Mori, H; Numoto, S; Williams, GM, 1985)
"The relationships between the shelf level at which mice were housed and body weight and food consumption/wastage were examined by analyzing data obtained from the first 9 months of a carcinogenic dose-response study carried out in 24,192 female BALB/c mice using 2-acetylaminofluorene (2-AAF) as the carcinogen."3.66Relationship of mouse body weight and food consumption/wastage to cage shelf level. ( Bryant, P; Greenman, DL; Kodell, RL; Sheldon, W, 1983)
"Acetaminophen was given in the diet either alone at 2400 or 4800 p."1.34Inhibition by acetaminophen of neoplastic initiation elicited in rat liver by the DNA-reactive hepatocarcinogen N-acetyl-2-aminofluorene. ( Duan, JD; Iatropoulos, MJ; Jeffrey, AM; Perrone, CE; Williams, GM, 2007)
"5 ppm dosage in drinking water in a defined model of a two-stage experimental rat hepatocarcinogenesis."1.33Vanadium inhibits the development of 2-acetylaminofluorene-induced premalignant phenotype in a two-stage chemical rat hepatocarcinogenesis model. ( Chakraborty, T; Chatterjee, A; Chatterjee, M; Dhachinamoorthi, D; Saralaya, MG, 2006)
" From 5 weeks after the completion of 2-AAF administration, the rats were orally dosed with 0."1.32Inhibitory effects of KAT-681, a liver-selective thyromimetic, on development of hepatocellular proliferative lesions in rats induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation. ( Akahane, M; Hayashi, M; Kuroda, J; Machida, N; Mitsumori, K; Moriwaki, H; Ohnota, H; Shibata, N; Tamura, T, 2004)
" At nodular and post-nodular stages biliary excretion of radioactive metabolites was decreased, although hepatic content of radioactivity was similar to controls not dosed with AAF."1.28Protein binding, nuclear translocation and biliary secretion of metabolites of 3'-methyl-N,N-dimethyl-4-aminoazobenzene during hepatocarcinogenesis in rats. ( Bhargava, MM; Levine, WG; Srinivasan, K, 1991)
" Each group consisted of 96 mice, except the groups of females dosed at 0 and 150 ppm, which consisted of 120 and 72 mice, respectively."1.28Increased incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors in B6C3F1 mice fed AIN-76A diet versus NIH-07 diet. ( Bucci, TJ; Fullerton, FR; Greenman, DL; McCarty, CC, 1991)
" However, sodium saccharin dosing did not result in an increased incidence of tumors in either the bladder or liver and is therefore not considered to be a promoter of carcinogenesis at these sites in the mouse."1.28The effect of lifetime sodium saccharin dosing on mice initiated with the carcinogen 2-acetylaminofluorene. ( Dooley, KL; Frederick, CB; Kadlubar, FF; Kodell, RL; Sheldon, WG, 1989)
"(c) Spermine levels were significantly lowered, with 3 minima corresponding to the putrescine maxima."1.26Intrahepatic polyamine levels during rat liver carcinogenesis induced by N-2-fluorenylacetamide. ( Aussel, C; Lafaurie, M; Lalanne, CM; Milano, G; Soula, G; Stora, C, 1981)
"Lower body weight was observed in operated rats but it is not considered to be the major cause of a complete inhibition of mammary tumor induction."1.26An inhibitory effect of salivary gland extirpation on the induction of mammary tumors in rats by N,N'-2,7-fluorenylenebisacetamide. ( Hirano, T; Jackson, CM; Lewis, JW; Morris, HP, 1976)

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-199033 (55.00)18.7374
1990's18 (30.00)18.2507
2000's9 (15.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furtado, KS1
Pires, PW1
Justulin, LA1
Rodrigues, MA1
Felisbino, SL1
Barbisan, LF2
Cui, R1
Wang, B1
Zhang, F1
Chen, G1
Yin, S1
Espandiari, P1
Glauert, HP1
Lehmler, HJ1
Lee, EY1
Srinivasan, C1
Robertson, LW1
Hayashi, M2
Ohnota, H2
Tamura, T2
Kuroda, J2
Shibata, N2
Akahane, M2
Moriwaki, H1
Machida, N1
Mitsumori, K2
Kashida, Y1
Chakraborty, T2
Samanta, S1
Ghosh, B1
Thirumoorthy, N1
Chatterjee, M2
Chatterjee, A1
Saralaya, MG1
Dhachinamoorthi, D1
Williams, GM7
Iatropoulos, MJ1
Jeffrey, AM1
Duan, JD1
Perrone, CE1
Laishes, BA2
Rolfe, PB1
Numoto, S2
Furukawa, K1
Furuya, K2
Hosaka, S1
Nagayama, H1
Hirono, I1
Greenman, DL4
Bryant, P1
Kodell, RL2
Sheldon, W1
Malejka-Giganti, D1
McIver, RC1
Rydell, RE1
Depass, LR1
Morris, MD1
Milano, G1
Aussel, C2
Stora, C3
Lafaurie, M3
Soula, G1
Lalanne, CM1
Mori, H7
Tanaka, T8
Nishikawa, A1
Takahashi, M2
Peraino, C2
Krebs, B2
Staffeldt, EF1
Haugen, DA1
Lombard, LS1
Stevens, FJ1
Fry, RJ1
Lok, E1
Mehta, R1
Jee, P1
Laver, G1
Nera, EA1
McMullen, E1
Clayson, DB1
La Porta, CA1
Comolli, R1
Storer, RD1
Cartwright, ME1
Cook, WO1
Soper, KA1
Nichols, WW1
Ho, YS1
Lin, JK1
Blanck, A1
Assefaw-Redda, Y1
Eriksson, LC1
Gustafsson, JA1
Ekvärn, S1
Hällström, IP1
Tokumo, K1
Umemura, T1
Sirma, H1
Gebhardt, R1
Poirier, MC1
Kojima, T1
Okumura, A1
Sugie, S2
Hagiwara, A1
Tanaka, H1
Imaida, K2
Tamano, S1
Fukushima, S1
Ito, N4
Pascale, RM1
Simile, MM1
DeMiglio, MR1
Muroni, MR1
Gaspa, L1
Dragani, TA1
Feo, F1
Danz, M1
Sänger, J1
Friedrichsen, K1
Linss, W1
Shimizu, I1
Yasuda, M1
Mizobuchi, Y1
Ma, YR1
Liu, F1
Shiba, M1
Horie, T1
Ito, S1
Spinardi-Barbisan, AL1
Kaneno, R1
Marchesan Rodrigues, MA1
Fávero Salvadori, DM1
Trindade Moreira, EL1
Viana de Camargo, JL1
Bushnell, DE1
Jeter, JR1
Yamamoto, RS1
Weisburger, EK2
Mohan, LC1
Grantham, PH1
Weisburger, JH2
Idoine, JB1
Hirano, T1
Morris, HP1
Jackson, CM1
Lewis, JW1
Littlefield, NA1
Cueto, C1
Davis, AK1
Medlock, K1
Goodman, JI1
Trosko, JE1
Yager, JD1
Reuber, MD1
Fullerton, FR2
Bucci, TJ2
Ogawa, K1
Hasegawa, R2
Wada, S1
Yamaguchi, S2
Srinivasan, K1
Levine, WG2
Bhargava, MM1
Takahashi, S1
Shirai, T1
Maruyama, H2
Maeura, Y1
Zang, E1
Takeuchi, T1
Shimizu, M1
Morishita, Y1
Mori, Y3
McCarty, CC1
Castelli, D1
Seralini, GE1
Frederick, CB1
Dooley, KL1
Sheldon, WG1
Kadlubar, FF1
Niwa, K2
Yoshimi, N1
Iwata, H2
Hara, A1
LeBoeuf, RA1
Hoekstra, WG1
Masui, T1
Tsuda, H1
Inoue, K1
Ogiso, T1
Shima, H1
Kuniyasu, T1
Muto, Y1
Rajpurohit, R1
Krishnaswamy, K1
Randerath, K1
Lu, LJ1
Li, D1
Shimizu, A1
Hiramatsu, N1
Kishida, T1
Natake, M1
Boothe, A1
Kodell, R1
Daoud, AH1
Griffin, AC1

Reviews

1 review available for 2-acetylaminofluorene and Body Weight

ArticleYear
The role of hormones on digestive and urinary tract carcinogenesis.
    Recent progress in hormone research, 1976, Volume: 33

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Carcinogens; Diet; Female; Food; Gonadal Steroid Hormon

1976

Other Studies

59 other studies available for 2-acetylaminofluorene and Body Weight

ArticleYear
Metalloproteinases 2 and 9 activity during promotion and progression stages of rat liver carcinogenesis.
    Journal of molecular histology, 2009, Volume: 40, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Diethylnitrosamine; Disease Progression; Glutathione S-

2009
Suppressive effect of herbal compound 861 on chemical hepatocarcinogenesis in rats.
    Chinese medical journal, 2003, Volume: 116, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Blotting, Northern; Blotting, Western; Body Weight; Diethylnitrosami

2003
Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 79, Issue:1

    Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Administration, Oral; Animals; Biphenyl Compounds; Body

2004
Inhibitory effects of KAT-681, a liver-selective thyromimetic, on development of hepatocellular proliferative lesions in rats induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation.
    Archives of toxicology, 2004, Volume: 78, Issue:8

    Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Body Weight; Carcinogens; Cell Proliferation; Diethylnitr

2004
Different inhibitory effects in the early and late phase of treatment with KAT-681, a liver-selective thyromimetic, on rat hepatocarcinogenesis induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 84, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Anticarcinogenic Agents; Apoptosis; Body Weight; Carcinogens; Cell P

2005
Vanadium induces apoptosis and modulates the expressions of metallothionein, Ki-67 nuclear antigen, and p53 during 2-acetylaminofluorene-induced rat liver preneoplasia.
    Journal of cellular biochemistry, 2005, Mar-01, Volume: 94, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Body Weight; DNA Damage; Gene Expression Regulation; Ki-6

2005
Vanadium inhibits the development of 2-acetylaminofluorene-induced premalignant phenotype in a two-stage chemical rat hepatocarcinogenesis model.
    Life sciences, 2006, May-08, Volume: 78, Issue:24

    Topics: 2-Acetylaminofluorene; Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Chromosome Aberra

2006
Inhibition by acetaminophen of neoplastic initiation elicited in rat liver by the DNA-reactive hepatocarcinogen N-acetyl-2-aminofluorene.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2007, Volume: 16, Issue:6

    Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Antineoplastic Agents; Body Weight; Carcinoma, Hepato

2007
Search for endogenous liver colony-forming units in F344 rats given a two-thirds hepatectomy during short-term feeding of 2-acetylaminofluorene.
    Cancer research, 1981, Volume: 41, Issue:5

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Clone Cells; Diet; DNA, Neoplasm; gamma-Glutamyltransfe

1981
Effects of the hepatocarcinogenic peroxisome-proliferating hypolipidemic agents clofibrate and nafenopin on the rat liver cell membrane enzymes gamma-glutamyltranspeptidase and alkaline phosphatase and on the early stages of liver carcinogenesis.
    Carcinogenesis, 1984, Volume: 5, Issue:12

    Topics: 2-Acetylaminofluorene; Alkaline Phosphatase; Animals; Body Weight; Cell Division; Cell Membrane; Clo

1984
Suppressive effect of caffeine on the development of hepatic tumors induced by 2-acetylaminofluorene in ACI rats.
    Gan, 1984, Volume: 75, Issue:12

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Caffeine; Drinking; Eating; Enzyme Induction; Liver Neo

1984
Relationship of mouse body weight and food consumption/wastage to cage shelf level.
    Laboratory animal science, 1983, Volume: 33, Issue:6

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Feeding Behavior; Female; Housing, Animal; Mice; Mice,

1983
Inhibitory effect of disulfiram on rat mammary tumor induction by N-2-fluorenylacetamide and on its metabolic conversion to N-hydroxy-N-2-fluorenylacetamide.
    Journal of the National Cancer Institute, 1980, Volume: 64, Issue:6

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenofibroma; Adenoma; Animals; Biotransformation; Body Weigh

1980
Feedback control of cholesterol biosynthesis in rats fed the liver carcinogens benzidine and 2-acetylaminofluorene.
    Cancer biochemistry biophysics, 1981, Volume: 5, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Benzidines; Body Weight; Cholesterol; Feedback; Liver; Male; Rats; S

1981
Intrahepatic polyamine levels during rat liver carcinogenesis induced by N-2-fluorenylacetamide.
    Carcinogenesis, 1981, Volume: 2, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Female; Liver Neoplasms; Neoplasms, Experimental; Organ

1981
Enhancing effect of barbital on N-2-fluorenylacetamide-induced rat liver lesions.
    Gan, 1981, Volume: 72, Issue:5

    Topics: 2-Acetylaminofluorene; Animals; Barbital; Barbiturates; Body Weight; Kinetics; Liver; Male; Organ Si

1981
Initiation and promotion of liver tumorigenesis.
    National Cancer Institute monograph, 1981, Issue:58

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Carcinogens; Kinetics; Liver Neoplasms; Neoplasms, Expe

1981
Modifications in adrenal activity during hepatocarcinogenesis by N-2-fluorenylacetamide.
    Steroids, 1980, Volume: 35, Issue:5

    Topics: 2-Acetylaminofluorene; Adrenal Glands; Aldosterone; Animals; Body Weight; Estradiol; Female; Liver N

1980
Effects of varying the dietary concentration of phenobarbital on its enhancement of 2-acetylaminofluorene-induced hepatic tumorigenesis.
    Cancer research, 1980, Volume: 40, Issue:9

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Diet; Dose-Response Relationship, Drug; Drug Synergism;

1980
The effect of butylated hydroxytoluene on the growth of enzyme-altered foci in male Fischer 344 rat liver tissue.
    Carcinogenesis, 1995, Volume: 16, Issue:5

    Topics: 2-Acetylaminofluorene; Analysis of Variance; Animals; Antioxidants; Body Weight; Butylated Hydroxyto

1995
Over-expression of protein kinase C delta is associated with a delay in preneoplastic lesion development in diethylnitrosamine-induced rat hepatocarcinogenesis.
    Carcinogenesis, 1995, Volume: 16, Issue:5

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Carcinogens; Caseins; Diet; Diethylnitrosamine; gamma-G

1995
Short-term carcinogenesis bioassay of genotoxic procarcinogens in PIM transgenic mice.
    Carcinogenesis, 1995, Volume: 16, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Benzene; Biotransformation; Body Weight; Carcinogenicity Tests; Carc

1995
N-nitroso-2-acetylaminofluorene: a direct-acting carcinogen inducing hepatocellular carcinoma in Sprague-Dawley rats.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:8

    Topics: 2-Acetylaminofluorene; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Body

1994
Growth hormone administration after treatment in the resistant hepatocyte model does not affect progression of rat liver carcinogenesis.
    Cancer letters, 1994, May-16, Volume: 79, Issue:2

    Topics: 2-Acetylaminofluorene; Androstenedione; Animals; Body Weight; Cell Division; Diethylnitrosamine; Fem

1994
Inhibition by gonadectomy of effects of 2-acetylaminofluorene in livers of male, but not female rats.
    Carcinogenesis, 1993, Volume: 14, Issue:9

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; DNA; Dose-Response Relationship, Drug; Female; Liver; M

1993
Inhibitory effect of the non-steroidal anti-inflammatory drugs, indomethacin and piroxicam on 2-acetylaminofluorene-induced hepatocarcinogenesis in male ACI/N rats.
    Cancer letters, 1993, Volume: 68, Issue:2-3

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Indomethacin; Liver; Liver Neoplasms, Experimental; Mal

1993
Correlation between medium-term multi-organ carcinogenesis bioassay data and long-term observation results in rats.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Butylated Hydroxyanisole; Carcinogenicity Tests; Carcin

1993
The BN rat strain carries dominant hepatocarcinogen resistance loci.
    Carcinogenesis, 1996, Volume: 17, Issue:8

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Carcinogens; Genes, Dominant; Genetic Predisposition to

1996
2-Acetylaminofluorene-produced selective cytotoxic damage of a ductal compartment and its repair in the submandibular gland of rats.
    Cell and tissue research, 1997, Volume: 288, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Cell Survival; Male; Mutagens; Organ Size; Rats; Rats,

1997
Suppressive effect of oestradiol on chemical hepatocarcinogenesis in rats.
    Gut, 1998, Volume: 42, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Biomarkers, Tumor; Body Weight; Diethylnitrosamine; Estradiol; Femal

1998
Lymphoproliferative response and T lymphocyte subsets in a medium-term multi-organ bioassay for carcinogenesis in Wistar rats.
    Cancer letters, 2000, Jun-30, Volume: 154, Issue:2

    Topics: 1,2-Dimethylhydrazine; 2-Acetylaminofluorene; Alkylating Agents; Animals; Body Weight; Butylhydroxyb

2000
Effects of 2-acetylaminofluorene on diurnal oscillations in nucleic acid metabolism in two classes of nuclei isolated from rat liver.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Cell Nucleus; Circadian Rhythm; DNA; Fasting; Fluorenes

1978
Mechanisms of the inhibitory action of p-hydroxyacetanilide on carcinogenesis by N-2-fluorenylacetamide or N-hydroxy-N-2-fluorenylacetamide.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:4

    Topics: 2-Acetylaminofluorene; Acetaminophen; Amidohydrolases; Animals; Body Weight; Eating; Feces; Fluorene

1976
An inhibitory effect of salivary gland extirpation on the induction of mammary tumors in rats by N,N'-2,7-fluorenylenebisacetamide.
    Acta pathologica japonica, 1976, Volume: 26, Issue:3

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Animals; Atrophy; Body Weight; Diet; Female; Fluorenes; Mamma

1976
Chronic dose-response studies in mice fed 2-AAF.
    Journal of toxicology and environmental health, 1975, Volume: 1, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Diet; Dose-Response Relationship, Drug; Female; Fluoren

1975
Studies on the mechanism of inhibition of 2-acetylaminofluorene toxicity by butylated hydroxytoluene.
    Chemico-biological interactions, 1976, Volume: 12, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Butylated Hydroxytoluene; Cell Nucleus; Cresols; DNA; D

1976
Effect of age and testosterone on the induction of hyperplastic nodules, carcinomas, and cirrhosis of the liver in rats ingesting n-2-fluorenyldiacetamide.
    European journal of cancer, 1976, Volume: 12, Issue:2

    Topics: 2-Acetylaminofluorene; Age Factors; Animals; Body Weight; Castration; Fluorenes; Hyperplasia; Liver

1976
Effects of diet type on incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors in BALB/c mice fed AIN-76A diet versus NIH-07 diet.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:2

    Topics: 2-Acetylaminofluorene; Adenoma; Animals; Body Weight; Carcinoma, Hepatocellular; Eating; Female; Foo

1992
Dose response study of N-nitrosodiethanolamine initiation of rat hepatocarcinogenesis.
    Teratogenesis, carcinogenesis, and mutagenesis, 1991, Volume: 11, Issue:5

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Cocarcinogenesi

1991
Protein binding, nuclear translocation and biliary secretion of metabolites of 3'-methyl-N,N-dimethyl-4-aminoazobenzene during hepatocarcinogenesis in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1991, Volume: 21, Issue:7

    Topics: 2-Acetylaminofluorene; Animals; Bile; Body Weight; Carcinogens; Cell Nucleus; Chromatography, Gel; C

1991
Age-dependent induction of preneoplastic liver cell foci by 2-acetylaminofluorene, phenobarbital and acetaminophen in F344 rats initially treated with diethylnitrosamine.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:3

    Topics: 2-Acetylaminofluorene; Acetaminophen; Aging; Animals; Biomarkers, Tumor; Body Weight; Carcinogens; D

1991
Modulation by butylated hydroxytoluene of liver and bladder carcinogenesis induced by chronic low-level exposure to 2-acetylaminofluorene.
    Cancer research, 1991, Dec-01, Volume: 51, Issue:23 Pt 1

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Butylated Hydroxytoluene; Dose-Response Relationship, D

1991
Modifying effects of anticancer drugs adriamycin, actinomycin D, and cisplatin on N-2-fluorenylacetamide-induced hepatocarcinogenesis in male ACI/N rats.
    Journal of toxicology and environmental health, 1991, Volume: 32, Issue:3

    Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Body Weight; Cisplatin; Dactinomycin; Doxorubi

1991
Increased incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors in B6C3F1 mice fed AIN-76A diet versus NIH-07 diet.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 16, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Diet; Eating; Energy Intake; Female; Growth; Liver Neop

1991
Ovarian function during aflatoxin B1-induced hepatocarcinogenesis in the rat.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 53, Issue:2

    Topics: 2-Acetylaminofluorene; Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Body Weight; Dietary P

1986
The effect of lifetime sodium saccharin dosing on mice initiated with the carcinogen 2-acetylaminofluorene.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1989, Volume: 12, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Diet; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H

1989
Induction of altered hepatocellular foci of hamster for a possible short-term assay for carcinogens.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 63, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Carbon Tetrachloride; Carcinogens; Cricetinae; Liver; M

1989
Effects of dietary selenium concentration on the development of enzyme-altered liver foci and hepatocellular carcinoma induced by diethylnitrosamine or N-acetylaminofluorene in rats.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 1

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Diet; Diethylnitrosamine; Dose-Response Relationship, D

1985
Inhibitory effect of ellagic acid on N-2-fluorenylacetamide-induced liver carcinogenesis in male ACI/N rats.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:12

    Topics: 2-Acetylaminofluorene; Animals; Benzopyrans; Body Weight; Ellagic Acid; gamma-Glutamyltransferase; L

1988
Inhibitory effects of ethoxyquin, 4,4'-diaminodiphenylmethane and acetaminophen on rat hepatocarcinogenesis.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:3

    Topics: 2-Acetylaminofluorene; Acetaminophen; Aniline Compounds; Animals; Body Weight; Butylated Hydroxyanis

1986
Inhibitory effects of polyprenoic acid (E-5166) on N-2-fluorenylacetamide-initiated hepatocarcinogenesis in rats.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Drug Antagonism; Liver; Liver Neoplasms, Experimental;

1986
Differences in response of glucuronide and glutathione conjugating enzymes to aflatoxin B1 and N-acetylaminofluorene in underfed rats.
    Journal of toxicology and environmental health, 1988, Volume: 24, Issue:1

    Topics: 2-Acetylaminofluorene; Administration, Oral; Aflatoxin B1; Aflatoxins; Animals; Aryl Hydrocarbon Hyd

1988
A comparison between different types of covalent DNA modifications (I-compounds, persistent carcinogen adducts and 5-methylcytosine) in regenerating rat liver.
    Carcinogenesis, 1988, Volume: 9, Issue:10

    Topics: 2-Acetylaminofluorene; 5-Methylcytosine; Adenosine Triphosphate; Animals; Body Weight; Cytosine; DNA

1988
Experimental studies on hepatic cirrhosis and hepatocarcinogenesis. II. Influence of cirrhotic liver on 2-FAA hepatocarcinogenesis in rats.
    Acta pathologica japonica, 1986, Volume: 36, Issue:7

    Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Body Weight; Furaldehyde; Histocytochemistry;

1986
Lack of rapid initiating, promoting or sequential syncarcinogenic effects of di(2-ethylhexyl)phthalate in rat liver carcinogenesis.
    Carcinogenesis, 1987, Volume: 8, Issue:7

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Cell Division; Cocarcinogenesis; Diethylhexyl Phthalate

1987
Effect of autoxidized linoleic acid on the contents of cytochrome P-450 and cytochrome b5, and drug-metabolizing enzyme activities in rat liver.
    Journal of nutritional science and vitaminology, 1987, Volume: 33, Issue:1

    Topics: 2-Acetylaminofluorene; Aminopyrine N-Demethylase; Animals; Body Weight; Cytochrome b Group; Cytochro

1987
Age-dependent responses to 2-acetylaminofluorene in BALB/c female mice.
    Journal of toxicology and environmental health, 1987, Volume: 22, Issue:2

    Topics: 2-Acetylaminofluorene; Aging; Animals; Body Weight; Environment; Female; Liver Neoplasms; Liver Neop

1987
Absence of a promoting or sequential syncarcinogenic effect in rat liver by the carcinogenic hypolipidemic drug nafenopin given after N-2-fluorenylacetamide.
    Toxicology and applied pharmacology, 1985, Volume: 77, Issue:1

    Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Body Weight; Carcinogens; Drug Synergism; Live

1985
Effect of retinoic acid, butylated hydroxytoluene, propylgallate and selenium on 2-acetylaminofluorene induced hepatotoxicity.
    Cancer letters, 1985, Volume: 29, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Butylated Hydroxytoluene; Drug Interactions; Female; Ga

1985