2-acetylaminofluorene has been researched along with Bile Duct Cancer in 5 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A rat cell line-nominated CC-62 derived from a combined hepatocellular and cholangiocellular carcinoma obtained by administration of 2-acetylaminofluorene to male Wistar rats, has been established." | 3.71 | Characterization of a new rat cell line established from 2'AAF-induced combined hepatocellular cholangiocellular carcinoma. ( Callaghan, R; Carda, C; Gil-Benso, R; Gregori-Romero, MA; Llombart-Bosch, A; Martinez-Lorente, A; Navarro-Fos, S; Pellin-Perez, A; Peydro-Olaya, A, 2001) |
| "Well to moderately well differentiated hepatocellular carcinomas developed in 50% and 75% of rats fed the CD + AAF diet for 4 and 6 months, respectively." | 1.26 | Enhancement of 2-acetylaminofluorene liver carcinogenesis in rats fed a choline-devoid diet. ( Lombardi, B; Shinozuka, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MORI, K | 1 |
| THERET, C | 2 |
| Gil-Benso, R | 1 |
| Martinez-Lorente, A | 1 |
| Pellin-Perez, A | 1 |
| Navarro-Fos, S | 1 |
| Gregori-Romero, MA | 1 |
| Carda, C | 1 |
| Callaghan, R | 1 |
| Peydro-Olaya, A | 1 |
| Llombart-Bosch, A | 1 |
| Lombardi, B | 1 |
| Shinozuka, H | 1 |
5 other studies available for 2-acetylaminofluorene and Bile Duct Cancer
| Article | Year |
|---|---|
Effect of liver feeding on the production of liver cancer of 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinogens; Humans; Liver Ext | 1954 |
[Experimental hepatic cancers. Selective modifications brought about by adrenaline and acetylcholine on the action of DAB and 2-AAF].
Topics: 2-Acetylaminofluorene; Acetylcholine; Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcin | 1961 |
[Facilitation, by chlorpromazine, of hepatic cancer production by 2-acetylaminofluorene in female Wistar rats].
Topics: 2-Acetylaminofluorene; Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Chlorpromazine; Femal | 1962 |
Characterization of a new rat cell line established from 2'AAF-induced combined hepatocellular cholangiocellular carcinoma.
Topics: 2-Acetylaminofluorene; Aneuploidy; Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma | 2001 |
Enhancement of 2-acetylaminofluorene liver carcinogenesis in rats fed a choline-devoid diet.
Topics: 2-Acetylaminofluorene; Adenoma, Bile Duct; Animals; Bile Duct Neoplasms; Carcinoma, Hepatocellular; | 1979 |