2-acetylaminofluorene has been researched along with Aneuploid in 4 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A rat cell line-nominated CC-62 derived from a combined hepatocellular and cholangiocellular carcinoma obtained by administration of 2-acetylaminofluorene to male Wistar rats, has been established." | 3.71 | Characterization of a new rat cell line established from 2'AAF-induced combined hepatocellular cholangiocellular carcinoma. ( Callaghan, R; Carda, C; Gil-Benso, R; Gregori-Romero, MA; Llombart-Bosch, A; Martinez-Lorente, A; Navarro-Fos, S; Pellin-Perez, A; Peydro-Olaya, A, 2001) |
| "In human hepatoma (Hep G2) cells and peripheral blood lymphocytes (HPBL) the cytokinesis-blocked micronuclei (MN) and fluorescent in situ hybridization (FISH) assays were applied to study aneugenic and clastogenic potentials of X-rays, directly and indirectly acting chemicals." | 1.29 | Detection of aneugenic and clastogenic potential of X-rays, directly and indirectly acting chemicals in human hepatoma (Hep G2) and peripheral blood lymphocytes, using the micronucleus assay and fluorescent in situ hybridization with a DNA centromeric pro ( Darroudi, F; Hadjidekova, V; Meijers, CM; Natarajan, AT, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Darroudi, F | 1 |
| Meijers, CM | 1 |
| Hadjidekova, V | 1 |
| Natarajan, AT | 1 |
| Parry, JM | 1 |
| Jenkins, GJ | 1 |
| Haddad, F | 1 |
| Bourner, R | 1 |
| Parry, EM | 1 |
| Gil-Benso, R | 1 |
| Martinez-Lorente, A | 1 |
| Pellin-Perez, A | 1 |
| Navarro-Fos, S | 1 |
| Gregori-Romero, MA | 1 |
| Carda, C | 1 |
| Callaghan, R | 1 |
| Peydro-Olaya, A | 1 |
| Llombart-Bosch, A | 1 |
| Becker, FF | 1 |
| Wolman, SR | 1 |
| Asofsky, R | 1 |
| Sell, S | 1 |
4 other studies available for 2-acetylaminofluorene and Aneuploid
| Article | Year |
|---|---|
Detection of aneugenic and clastogenic potential of X-rays, directly and indirectly acting chemicals in human hepatoma (Hep G2) and peripheral blood lymphocytes, using the micronucleus assay and fluorescent in situ hybridization with a DNA centromeric pro
Topics: 2-Acetylaminofluorene; Aneuploidy; Carcinoma, Hepatocellular; Cell Nucleus; Centromere; Colchicine; | 1996 |
In vitro and in vivo extrapolations of genotoxin exposures: consideration of factors which influence dose-response thresholds.
Topics: 1,2-Dimethylhydrazine; 2-Acetylaminofluorene; Amino Acid Substitution; Aneuploidy; Animals; Cells, C | 2000 |
Characterization of a new rat cell line established from 2'AAF-induced combined hepatocellular cholangiocellular carcinoma.
Topics: 2-Acetylaminofluorene; Aneuploidy; Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma | 2001 |
Sequential analysis of transplantable hepatocellular carcinomas.
Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Aneuploidy; Animals; Blood Proteins; Carcinoma, Hepatocel | 1975 |