2-acetylaminofluorene has been researched along with Adenoma in 15 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Adenoma: A benign epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The nuclear pore density and area were measured on freeze-fractured nuclei of ACI/N rat liver altered foci, adenomas and carcinomas induced by 2-acetylaminofluorene, and compared with those of normal hepatocytes." | 3.69 | Alterations of nuclear pores in preneoplastic and neoplastic rat liver lesions induced by 2-acetylaminofluorene. ( Mori, H; Sugie, S; Tanaka, T; Williams, GM; Yoshimi, N, 1994) |
| " Two diets used widely in toxicological and/or nutritional studies, and considered to be nutritionally adequate, were compared with respect to their influence on growth, body weight, lifespan, spontaneous neoplasia, and neoplastic responses to 2-acetylaminofluorene (2-AAF)." | 3.68 | Effects of diet type on incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors in BALB/c mice fed AIN-76A diet versus NIH-07 diet. ( Bucci, TJ; Fullerton, FR; Greenman, DL, 1992) |
| " The data indicate that at least in hepatocellular tumours of the C57Bl/10J strain and using chronic dosing regimes the ras genes do not represent markers for in vivo genotoxic activity." | 1.28 | Point mutation analysis of ras genes in spontaneous and chemically induced C57Bl/10J mouse liver tumours. ( Hardaker, KJ; Lord, PG; Loughlin, JM; Marsden, AM; Orton, TC, 1992) |
| "Pulmonary metastases occurred only in the tubulopleomorphic adenocarcinomas." | 1.26 | Morphologic characteristics of benign and malignant renal cell tumors in control and 2-acetylaminofluorene-treated BALB/c female mice. ( Frith, CH; Shinohara, Y, 1980) |
| "These neoplasms included cholangiomas, hepatoadenomas, cholangiocarcinomas, and hepatocellular cancers." | 1.25 | Tumor induction by carcinogenic agents in aquarium fish. ( Khudoley, VV; Pliss, GB, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DONIACH, I | 1 |
| Malejka-Giganti, D | 2 |
| McIver, RC | 1 |
| Rydell, RE | 1 |
| Shinohara, Y | 1 |
| Frith, CH | 1 |
| Sugie, S | 1 |
| Yoshimi, N | 1 |
| Tanaka, T | 3 |
| Mori, H | 1 |
| Williams, GM | 3 |
| Chen, JJ | 1 |
| Pliss, GB | 1 |
| Khudoley, VV | 1 |
| Matsushima, T | 1 |
| Sugimura, T | 1 |
| Fullerton, FR | 1 |
| Greenman, DL | 1 |
| Bucci, TJ | 1 |
| Lord, PG | 1 |
| Hardaker, KJ | 1 |
| Loughlin, JM | 1 |
| Marsden, AM | 1 |
| Orton, TC | 1 |
| Poirier, MC | 1 |
| Fullerton, NF | 1 |
| Kinouchi, T | 1 |
| Smith, BA | 1 |
| Beland, FA | 1 |
| Gebhardt, R | 2 |
| Maruyama, H | 1 |
| Berghem, L | 1 |
| Sorof, S | 1 |
| Custer, RP | 1 |
| Hoch-Ligeti, C | 1 |
| Wagner, BP | 1 |
| Deringer, MK | 1 |
| Stewart, HL | 1 |
1 review available for 2-acetylaminofluorene and Adenoma
| Article | Year |
|---|---|
Experimental carcinogenesis in small aquarium fishes.
Topics: 2-Acetylaminofluorene; Adenoma; Adenoma, Bile Duct; Aflatoxins; Animals; Benzopyrenes; Carcinogens; | 1976 |
14 other studies available for 2-acetylaminofluorene and Adenoma
| Article | Year |
|---|---|
The effect of radioactive iodine alone and in combination with methylthiouracil and acetylaminofluorene upon tumour production in the rat's thyroid gland.
Topics: 2-Acetylaminofluorene; Adenoma; Iodine; Iodine Compounds; Lymphoma, Non-Hodgkin; Methylthiouracil; N | 1950 |
Activation of certain N-arylacetamides and N-arylacetohydroxamic acids in relation to mammary gland tumorigenesis in the rat.
Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenofibroma; Adenoma; Animals; Biotransformation; Carcinogen | 1981 |
Inhibitory effect of disulfiram on rat mammary tumor induction by N-2-fluorenylacetamide and on its metabolic conversion to N-hydroxy-N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenofibroma; Adenoma; Animals; Biotransformation; Body Weigh | 1980 |
Morphologic characteristics of benign and malignant renal cell tumors in control and 2-acetylaminofluorene-treated BALB/c female mice.
Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenoma; Animals; Carcinoma, Papillary; Cystadenoma; Female; | 1980 |
Alterations of nuclear pores in preneoplastic and neoplastic rat liver lesions induced by 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Adenoma; Animals; Cell Nucleus; Disease Models, Animal; Freeze Fracturing; Li | 1994 |
Global tests for analysis of multiple tumour data from animal carcinogenicity experiments.
Topics: 2-Acetylaminofluorene; Adenoma; Animals; Biological Assay; Carcinogenicity Tests; Carcinogens; Carci | 1996 |
Tumor induction by carcinogenic agents in aquarium fish.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Adenoma, Bile Duct | 1975 |
Effects of diet type on incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors in BALB/c mice fed AIN-76A diet versus NIH-07 diet.
Topics: 2-Acetylaminofluorene; Adenoma; Animals; Body Weight; Carcinoma, Hepatocellular; Eating; Female; Foo | 1992 |
Point mutation analysis of ras genes in spontaneous and chemically induced C57Bl/10J mouse liver tumours.
Topics: 2-Acetylaminofluorene; Adenoma; Aminobiphenyl Compounds; Animals; Base Sequence; Carcinoma; Diethyln | 1992 |
Comparison between DNA adduct formation and tumorigenesis in livers and bladders of mice chronically fed 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Adenoma; Animals; Autoradiography; Carcinoma; Chromatography, High Pressure L | 1991 |
Glutamine synthetase heterogeneous expression as a marker for the cellular lineage of preneoplastic and neoplastic liver populations.
Topics: 2-Acetylaminofluorene; Adenoma; Aflatoxin B1; Aflatoxins; Animals; Biomarkers, Tumor; Diethylnitrosa | 1989 |
Decreased fibronectin in rat liver altered foci and adenomas induced by N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Adenoma; Animals; Fibronectins; Liver; Liver Neoplasms; Male; Precancerous Co | 1988 |
Elevated expression and cell cycle deregulation of a mitosis-associated target polypeptide of a carcinogen in hyperplastic and malignant rat hepatocytes.
Topics: 2-Acetylaminofluorene; Adenoma; Animals; Cell Cycle; Hyperplasia; Liver; Liver Neoplasms, Experiment | 1987 |
Tumor induction in Praomys (Mastomys) natalensis by N,N'-2,7-fluorenylenebisacetamide.
Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenoma; Adrenal Gland Neoplasms; Animals; Carcinogens; Diges | 1985 |