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2-acetylaminofluorene and Adenoma, Hepatocellular

2-acetylaminofluorene has been researched along with Adenoma, Hepatocellular in 5 studies

2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

Research Excerpts

ExcerptRelevanceReference
"Fumonisin B1 (FB1) is a naturally occurring mycotoxin produced by Fusarium verticillioides."1.32Fumonisin B1-induced hepatocellular and cholangiocellular tumors in male Fischer 344 rats: potentiating effects of 2-acetylaminofluorene on oval cell proliferation and neoplastic development in a discontinued feeding study. ( Gelderblom, WC; Hall, Pde L; Kirsch, RE; Lemmer, ER; Marasas, WF; Shephard, EG; Van Schalkwyk, DJ; Van Wijk, RA; Vessey, CJ, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González de Mejía, E1
Ramírez-Mares, MV1
Arce-Popoca, E1
Wallig, M1
Villa-Treviño, S1
Espandiari, P1
Glauert, HP1
Lehmler, HJ1
Lee, EY1
Srinivasan, C1
Robertson, LW1
Lemmer, ER1
Vessey, CJ1
Gelderblom, WC1
Shephard, EG1
Van Schalkwyk, DJ1
Van Wijk, RA1
Marasas, WF1
Kirsch, RE1
Hall, Pde L1
Hambali, Z1
Ngah, WZ1
Wahid, SA1
Kadir, KA1
Shoji, Y1
Kaneda, K1
Wake, K1
Mishima, Y1

Other Studies

5 other studies available for 2-acetylaminofluorene and Adenoma, Hepatocellular

ArticleYear
Inhibition of liver carcinogenesis in Wistar rats by consumption of an aqueous extract from leaves of Ardisia compressa.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2004, Volume: 42, Issue:3

    Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Animals; Antineoplastic Agents; Ardisia; Carcinogens; Ca

2004
Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 79, Issue:1

    Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Administration, Oral; Animals; Biphenyl Compounds; Body

2004
Fumonisin B1-induced hepatocellular and cholangiocellular tumors in male Fischer 344 rats: potentiating effects of 2-acetylaminofluorene on oval cell proliferation and neoplastic development in a discontinued feeding study.
    Carcinogenesis, 2004, Volume: 25, Issue:7

    Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Animals; Carcinogens; Carcinogens, Environmental; Carcin

2004
Effect of ovariectomy and sex hormone replacement on glutathione and glutathione-related enzymes in rat hepatocarcinogenesis.
    Pathology, 1995, Volume: 27, Issue:1

    Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Animals; Diethylnitrosamine; Estradiol; Female; Glutathi

1995
Light and electron microscopic analysis of liver sinusoids during hepatocarcinogenesis with 2-acetylaminofluorene in rats.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:5

    Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Mal

1994