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2-acetylaminofluorene and Adenocarcinoma

2-acetylaminofluorene has been researched along with Adenocarcinoma in 11 studies

2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"Other malignant neoplasms, including leiomyosarcomas, granulosa cells tumors, adrenocortical carcinomas, angiosarcomas, squamous cell carcinomas, and harderian gland tumors, metastasized at an incidence of less than 5%."1.26Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide. ( Frith, CH; Littlefield, NA; Umholtz, R, 1981)
"Pulmonary metastases occurred only in the tubulopleomorphic adenocarcinomas."1.26Morphologic characteristics of benign and malignant renal cell tumors in control and 2-acetylaminofluorene-treated BALB/c female mice. ( Frith, CH; Shinohara, Y, 1980)
"Lower body weight was observed in operated rats but it is not considered to be the major cause of a complete inhibition of mammary tumor induction."1.26An inhibitory effect of salivary gland extirpation on the induction of mammary tumors in rats by N,N'-2,7-fluorenylenebisacetamide. ( Hirano, T; Jackson, CM; Lewis, JW; Morris, HP, 1976)
"These neoplasms included cholangiomas, hepatoadenomas, cholangiocarcinomas, and hepatocellular cancers."1.25Tumor induction by carcinogenic agents in aquarium fish. ( Khudoley, VV; Pliss, GB, 1975)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199011 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ZUSSMAN, WV1
Frith, CH2
Littlefield, NA1
Umholtz, R1
Li, SA1
Malejka-Giganti, D3
Li, JJ1
McIver, RC1
Rydell, RE1
Ohmori, T1
Watanabe, K1
Williams, GM1
Allaben, WT1
Weeks, CE1
Weis, CC1
Burger, GT1
King, CM1
Shinohara, Y1
Pliss, GB1
Khudoley, VV1
Hirano, T1
Morris, HP1
Jackson, CM1
Lewis, JW1
Hoch-Ligeti, C1
Wagner, BP1
Deringer, MK1
Stewart, HL1

Other Studies

11 other studies available for 2-acetylaminofluorene and Adenocarcinoma

ArticleYear
SALIVARY AND SEBACEOUS GLAND ALTERATIONS IN RATS INGESTING N-2 FLUORENYLACETAMIDE.
    Archives of pathology, 1965, Volume: 80

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Atrophy; Carcinogens; Diethylstilbestrol; Ear Canal; Fluorene

1965
Incidence of pulmonary metastases for various neoplasms in BALB/cStCrlfC3H/Nctr female fed N-2-fluorenylacetamide.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:4

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Animals; Carcinogens; Female; Fibrosarcoma; Kidney Neoplasms;

1981
Steroid hormone receptors in the rat mammary adenocarcinoma induced by N-hydroxy-N-2-fluorenylacetamide.
    Journal of the National Cancer Institute, 1982, Volume: 69, Issue:1

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Animals; Breast Neoplasms; Castration; Centrifugation, Densit

1982
Activation of certain N-arylacetamides and N-arylacetohydroxamic acids in relation to mammary gland tumorigenesis in the rat.
    National Cancer Institute monograph, 1981, Issue:58

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenofibroma; Adenoma; Animals; Biotransformation; Carcinogen

1981
Inhibitory effect of disulfiram on rat mammary tumor induction by N-2-fluorenylacetamide and on its metabolic conversion to N-hydroxy-N-2-fluorenylacetamide.
    Journal of the National Cancer Institute, 1980, Volume: 64, Issue:6

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenofibroma; Adenoma; Animals; Biotransformation; Body Weigh

1980
Absence of uniform progressive growth of long-term transplants of rat liver neoplastic nodules.
    Journal of the National Cancer Institute, 1980, Volume: 65, Issue:2

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Animals; Liver Neoplasms; Male; Neoplasm Transplantation; Neo

1980
Rat mammary gland carcinogenesis after local injection of N-hydroxy-N-acyl-2-aminofluorenes: relationship to metabolic activation.
    Carcinogenesis, 1982, Volume: 3, Issue:3

    Topics: 2-Acetylaminofluorene; Acetyltransferases; Acyltransferases; Adenocarcinoma; Adenofibroma; Animals;

1982
Morphologic characteristics of benign and malignant renal cell tumors in control and 2-acetylaminofluorene-treated BALB/c female mice.
    The American journal of pathology, 1980, Volume: 100, Issue:2

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenoma; Animals; Carcinoma, Papillary; Cystadenoma; Female;

1980
Tumor induction by carcinogenic agents in aquarium fish.
    Journal of the National Cancer Institute, 1975, Volume: 55, Issue:1

    Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Adenoma, Bile Duct

1975
An inhibitory effect of salivary gland extirpation on the induction of mammary tumors in rats by N,N'-2,7-fluorenylenebisacetamide.
    Acta pathologica japonica, 1976, Volume: 26, Issue:3

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Animals; Atrophy; Body Weight; Diet; Female; Fluorenes; Mamma

1976
Tumor induction in Praomys (Mastomys) natalensis by N,N'-2,7-fluorenylenebisacetamide.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:4

    Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenoma; Adrenal Gland Neoplasms; Animals; Carcinogens; Diges

1985