2-acetylaminofluorene has been researched along with Acrania in 4 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Harris, C | 3 |
Stark, KL | 3 |
Luchtel, DL | 1 |
Juchau, MR | 4 |
Faustman-Watts, EM | 1 |
Namkung, MJ | 1 |
Greenaway, JC | 1 |
4 other studies available for 2-acetylaminofluorene and Acrania
Article | Year |
---|---|
Abnormal neurulation induced by 7-hydroxy-2-acetylaminofluorene and acetaminophen: evidence for catechol metabolites as proximate dysmorphogens.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Acetaminophen; Animals; Biological Availability; | 1989 |
Modulation of the embryotoxicity and cytotoxicity elicited by 7-hydroxy-2-acetylaminofluorene and acetaminophen via deacetylation.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Acetaminophen; Acetylation; Animals; Cell Surviv | 1989 |
Glutathione status and the incidence of neural tube defects elicited by direct acting teratogens in vitro.
Topics: 2-Acetylaminofluorene; Animals; Cytochalasin D; Cytochalasins; Female; Glutathione; Hydroxyacetylami | 1988 |
Analysis of metabolites of 2-acetylaminofluorene generated in an embryo culture system. Relationship of biotransformation to teratogenicity in vitro.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Animals; Biotransformation; Chromatography, High | 1985 |