Compounds > 2-acetyl-4(5)-tetrahydroxybutylimidazole
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2-acetyl-4(5)-tetrahydroxybutylimidazole and Lymphocytopenia

2-acetyl-4(5)-tetrahydroxybutylimidazole has been researched along with Lymphocytopenia in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's6 (60.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abe, K; Chiba, J; Hagihara, K; Hashimoto, R; Inoue, R; Kita, Y; Kobayashi, Y; Machinaga, N; Muro, F; Nagasaki, M; Ohtoyo, M; Shimozato, T; Tamura, M; Watanabe, J; Yuita, H1
Cyster, JG; Huang, Y; Matloubian, M; Pereira, JP; Schwab, SR; Xu, Y1
Gugasyan, R; Losinno, C; Mandel, T1
Oskarsson, A; Thuvander, A1
Gobin, SJ; Legg, RF; Paine, AJ1
Koulmanda, M; Mackay, IR; Mandel, TE1
Gobin, SJ; Phillips, JA1
Paine, AJ; Phillips, JA1
Gobin, SJ; Legg, RF; Paine, AJ; Phillips, JA1
Gobin, SJ; Paine, AJ1

Other Studies

10 other study(ies) available for 2-acetyl-4(5)-tetrahydroxybutylimidazole and Lymphocytopenia

ArticleYear
Component of Caramel Food Coloring, THI, Causes Lymphopenia Indirectly via a Key Metabolic Intermediate.
    Cell chemical biology, 2016, 05-19, Volume: 23, Issue:5

    Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Food Coloring Agents; Imidazoles; Lymphopenia; Lysophospholipids; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred Lew; Sphingosine; Structure-Activity Relationship

2016
Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients.
    Science (New York, N.Y.), 2005, Sep-09, Volume: 309, Issue:5741

    Topics: Aldehyde-Lyases; Animals; B-Lymphocytes; Chemotaxis, Leukocyte; Enzyme Inhibitors; Food Coloring Agents; Hematopoietic Stem Cells; Imidazoles; Immunosuppressive Agents; Lymph; Lymph Nodes; Lymphoid Tissue; Lymphopenia; Lysophospholipids; Mice; Mice, Inbred C57BL; Pyridoxine; Receptors, Lysosphingolipid; RNA Interference; Sphingosine; T-Lymphocytes; Thymus Gland; Vitamin B 6

2005
The effect of 2-acetyl-4-tetrahydroxybutylimidazole on lymphocyte subsets during a contact hypersensitivity response in the NOD mouse.
    Immunology letters, 1995, Volume: 46, Issue:3

    Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Count; Dermatitis, Contact; Female; Imidazoles; Immunosuppressive Agents; Lymph Nodes; Lymphopenia; Mice; Mice, Inbred NOD; T-Lymphocyte Subsets

1995
Effects of subchronic exposure to Caramel Colour III on the immune system in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:1

    Topics: Animals; Antibodies, Viral; Antigens, Viral; Candy; Carbohydrates; Diet; Female; Food Coloring Agents; Imidazoles; Immunity; Immunosuppressive Agents; Interleukin-2; Killer Cells, Natural; Lymphocyte Activation; Lymphopenia; Mice; Mice, Inbred BALB C; Organic Chemicals; Orthomyxoviridae; Pyridoxine

1994
The role of lymphocyte production and migration in the lymphopenia caused by 2-acetyl-4-tetrahydroxybutyl imidazole.
    International journal of immunopharmacology, 1992, Volume: 14, Issue:4

    Topics: Administration, Oral; Animals; Cell Division; Cell Movement; Food Coloring Agents; Imidazoles; Immunohistochemistry; Lymphocytes; Lymphopenia; Male; Rats; Rats, Inbred F344; Tissue Distribution

1992
Prevention of spontaneous and cyclophosphamide-induced diabetes in non-obese diabetic (NOD) mice with oral 2-acetyl-4-tetrahydroxybutylimidazole (THI), a component of caramel colouring III.
    Clinical and experimental immunology, 1992, Volume: 88, Issue:3

    Topics: Administration, Oral; Animals; CD4 Antigens; CD8 Antigens; Cyclophosphamide; Diabetes Mellitus, Type 1; Female; Flow Cytometry; Imidazoles; Lymphopenia; Mice; Mice, Inbred NOD; Spleen; T-Lymphocytes; Thymus Gland

1992
Immunosuppressive effects of 2-acetyl-4-tetrahydroxybutyl imidazole (THI) in the rat.
    Clinical and experimental immunology, 1991, Volume: 85, Issue:2

    Topics: Animals; Cell Division; Diet; Flow Cytometry; Hypersensitivity, Delayed; Imidazoles; Immunity, Cellular; Immunosuppressive Agents; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Lymphopenia; Male; Organ Size; Rats; Rats, Inbred F344

1991
Effect of pyridoxine on the disposition and lymphopenic effects of 2-acetyl-4(5)-tetrahydroxybutyl imidazole in the rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:6

    Topics: Animals; Binding, Competitive; Diet; Fasting; Imidazoles; Kinetics; Lymph Nodes; Lymphopenia; Male; Peyer's Patches; Pyridoxine; Rats; Spleen

1990
The effect of 2-acetyl-4-tetrahydroxybutylimidazole on lymphocyte subsets in peripheral blood of the rat.
    International journal of immunopharmacology, 1989, Volume: 11, Issue:8

    Topics: Animals; B-Lymphocytes; Candy; Carbohydrates; Food Coloring Agents; Imidazoles; Leukocyte Count; Lymphocytes; Lymphocytes, Null; Lymphopenia; Male; Organic Chemicals; Rats; T-Lymphocytes

1989
Effect of oral and parenteral administration of B6 vitamers on the lymphopenia produced by feeding ammonia caramel or 2-acetyl-4(5)-(1,2,3,4-tetrahydroxy)butylimidazole to rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1989, Volume: 27, Issue:10

    Topics: Administration, Oral; Animals; Candy; Carbohydrates; Diet; Drug Synergism; Food Coloring Agents; Imidazoles; Infusions, Parenteral; Intestinal Absorption; Leukocyte Count; Lymphopenia; Male; Nutritional Requirements; Organic Chemicals; Pyridoxine; Rats; Water Supply

1989