Compounds > 2,8-dihydroxyadenine
Page last updated: 2024-08-26

2,8-dihydroxyadenine and Fibrosis

2,8-dihydroxyadenine has been researched along with Fibrosis in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Boor, P; Buhl, EM; Dehairs, J; Jankowski, J; Klinkhammer, BM; Krueger, K; Lebherz, C; Lehrke, M; Marx, N; Moellmann, J; Noels, H; Swinnen, JV; Wong, DWL1
Arias, SC; Barlette, GP; Borges, RL; Camara, NO; de Almeida, DC; Fanelli, C; Fujihara, CK; Machado, FG; Malheiros, DM; Okabe, C; Zatz, R1
Aizawa, R; Hori, M; Ozaki, H; Tamura, M1
Boivin, G; Chen, J; Davies, PM; Engle, SJ; Sahota, A; Simmonds, HA; Stambrook, PJ; Stockelman, MG; Tischfield, JA; Ying, MY; Yum, MN1

Other Studies

4 other study(ies) available for 2,8-dihydroxyadenine and Fibrosis

ArticleYear
2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function.
    Biochimica et biophysica acta. Molecular basis of disease, 2024, Volume: 1870, Issue:1

    Topics: Adenine; Animals; Fibrosis; Inflammation; Kidney; Mice; Mice, Inbred C57BL; Mitochondria; Renal Insufficiency, Chronic; Sirtuin 3; TOR Serine-Threonine Kinases

2024
NF-κB activation mediates crystal translocation and interstitial inflammation in adenine overload nephropathy.
    American journal of physiology. Renal physiology, 2013, Jul-15, Volume: 305, Issue:2

    Topics: Adenine; Animals; Disease Models, Animal; Fibrosis; Granuloma; Inflammation Mediators; Kidney; Male; Nephritis, Interstitial; Nephrosclerosis; NF-kappa B; Pyrrolidines; Rats; Rats, Wistar; Thiocarbamates

2013
Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model.
    Histochemistry and cell biology, 2009, Volume: 131, Issue:4

    Topics: Actins; Adenine; Animals; Chemokines; Chemotaxis; Collagen; Cytokines; Disease Models, Animal; Fibrosis; Kidney Tubules; Macrophages; Male; Mice; Mice, Inbred C57BL; Nephritis, Interstitial

2009
Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11

    Topics: Adenine; Adenine Phosphoribosyltransferase; Alleles; Animals; Erythrocytes; Fibrosis; Homozygote; Humans; Inflammation; Kidney; Kidney Calculi; Mice; Mice, Knockout; Necrosis; Recombination, Genetic; Restriction Mapping; Stem Cells

1996