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2,5-hexanedione and Peripheral Nerve Diseases

2,5-hexanedione has been researched along with Peripheral Nerve Diseases in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (57.14)	18.7374
1990's	5 (17.86)	18.2507
2000's	3 (10.71)	29.6817
2010's	4 (14.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Li, M; Li, X; Wang, Q; Wang, S; Xie, K; Zhang, C	1
Gavin, T; LoPachin, RM	1
Bin, P; Chen, H; Dai, Y; Duan, H; Liu, Q; Niu, Y; Zheng, Y	1
Bin, P; Chen, H; Dai, Y; Duan, H; Liu, Q; Niu, Y; Zhao, L; Zheng, Y	1
Cangiano, A; Lutzemberger, L; Rizzuto, N; Rossi, A; Simonati, A; Toschi, G	1
Calisti, R; Governa, M; Martini, M; Tagliavento, G	1
Bus, JS; Gillies, PJ; Norton, RM	2
Bus, JS; Gillies, PJ; Norton, RM; White, EL	1
Baker, TS; Bus, JS; Gillies, PJ; Norton, RM	1
Sterman, AB	1
Eto, K; Misumi, J; Nagano, M; Nomura, S; Sato, K	1
Dyer, KS; Jortner, BS; Lehning, EJ; LoPachin, RM	1
Fujii, T; Fujikake, N; Komatsu, T; Ogawa, Y; Tanaka, J	1
Futatsuka, M; Kudo, M; Misumi, J; Nagano, M; Zhao, W	1
Arezzo, JC; Fox, JH; Jortner, BS; Kitano, T; Lehning, EJ; LoPachin, RM	1
Chiu, FC; He, DK; Lehning, EJ; LoPachin, RM; Opanashuk, LA	1
He, DK; Lehning, EJ; LoPachin, RM; Opanashuk, LA	1
Schaumburg, HH; Spencer, PS	1
Bertolazzi, M; Capodicasa, E; Lotti, M; Moretto, A; Peraica, M; Richardson, RJ; Scapellato, ML	1
Amarnath, V; Anthony, DC; Graham, DG; St Clair, MB	1
Braendgaard, H; Sidenius, P	1
Sickles, DW	1
Autilio-Gambetti, L; Gambetti, P; Monaco, S; Zabel, D	1
Hitoshi, T; Kaisaku, J; Misumi, J; Nagano, M	1
Couri, D; Milks, MM	1
Calisti, R; Colombi, A; Coppa, G; Governa, M; Tagliavento, G; Troni, W	1
Carden, MJ; Lee, VM; Schlaepfer, WW	1

Reviews

3 review(s) available for 2,5-hexanedione and Peripheral Nerve Diseases

Article	Year
Toxic neuropathies: Mechanistic insights based on a chemical perspective. Neuroscience letters, 2015, Jun-02, Volume: 596 Topics: Axons; Central Nervous System Diseases; Environmental Pollutants; Hexanones; Humans; Peripheral Nervous System Diseases	2015
[Polyneuropathies in shoe factory workers]. Recenti progressi in medicina, 1984, Volume: 75, Issue:5 Topics: Electromyography; Hexanes; Hexanones; Humans; Italy; Occupational Diseases; Peripheral Nervous System Diseases; Shoes; Tritolyl Phosphates	1984
Molecular mechanisms of gamma-diketone neuropathy. Advances in experimental medicine and biology, 1991, Volume: 283 Topics: Animals; Axons; Biotransformation; Hexanes; Hexanones; Humans; Methyl n-Butyl Ketone; Peripheral Nervous System Diseases; Structure-Activity Relationship	1991

Other Studies

25 other study(ies) available for 2,5-hexanedione and Peripheral Nerve Diseases

Article	Year
Hair pyrrole adducts serve as biomarkers for peripheral nerve impairment induced by 2,5-hexanedione and n-hexane in rats. PloS one, 2018, Volume: 13, Issue:12 Topics: Animals; Biomarkers; Hair; Hexanes; Hexanones; Male; Peripheral Nervous System Diseases; Pyrroles; Rats; Rats, Wistar	2018
The effect of 2,5-hexanedione on permeability of blood-nerve barrier in rats. Human & experimental toxicology, 2010, Volume: 29, Issue:6 Topics: Animals; Blood-Nerve Barrier; Body Weight; Disease Models, Animal; Evans Blue; Fluorescent Dyes; Gait; Hexanes; Hexanones; Male; Organ Specificity; Peripheral Nervous System Agents; Peripheral Nervous System Diseases; Permeability; Random Allocation; Rats; Rats, Wistar; Sciatic Nerve; Severity of Illness Index; Tibial Nerve; Time Factors	2010
[Effect of 2,5-hexanedione on myelin protein zero in sciatic nerve and its antibody in serum of rats at different time points]. Wei sheng yan jiu = Journal of hygiene research, 2010, Volume: 39, Issue:3 Topics: Animals; Antibodies; Hexanones; Male; Myelin P0 Protein; Peripheral Nervous System Diseases; Random Allocation; Rats; Rats, Wistar; Sciatic Nerve; Time Factors	2010
Neurotoxic effects of 2,5-hexanedione in rats: early morphological and functional changes in nerve fibres and neuromuscular junctions. Neurotoxicology, 1981, Volume: 2, Issue:1 Topics: Animals; Electrophysiology; Hexanones; Male; Muscle, Skeletal; Nerve Fibers; Neuromuscular Junction; Neurotoxins; Peripheral Nerves; Peripheral Nervous System Diseases; Rats; Rats, Wistar	1981
Effect of 2,5-Hexanedione on lipid biosynthesis in sciatic nerve and brain of the rat. Toxicology and applied pharmacology, 1980, Jun-30, Volume: 54, Issue:2 Topics: Animals; Body Weight; Brain; Drinking; Eating; Hexanones; In Vitro Techniques; Ketones; Lipids; Male; Peripheral Nervous System Diseases; Rats; Rats, Inbred F344; Sciatic Nerve	1980
Inhibition of sciatic nerve sterologenesis in hexacarbon-induced distal axonopathy in the rat. Toxicology and applied pharmacology, 1980, Jun-30, Volume: 54, Issue:2 Topics: Acetates; Animals; Hexanones; In Vitro Techniques; Ketones; Male; Mevalonic Acid; Peripheral Nervous System Diseases; Rats; Rats, Inbred F344; Sciatic Nerve; Sterols; Time Factors	1980
Inhibition of sterologenesis but not glycolysis in 2,5-hexanedione-induced distal axonopathy in the rat. Toxicology and applied pharmacology, 1981, Jun-30, Volume: 59, Issue:2 Topics: Acetates; Animals; Axons; Diet; Glucose; Glycolysis; Hexanones; Iodoacetates; Iodoacetic Acid; Ketones; Lipid Metabolism; Male; Peripheral Nervous System Diseases; Rats; Sciatic Nerve; Sterols	1981
Altered lipid metabolism in 2,5-hexanedione-induced testicular atrophy and peripheral neuropathy in the rat. Toxicology and applied pharmacology, 1981, Jun-30, Volume: 59, Issue:2 Topics: Acetates; Animals; Atrophy; Hexanones; Ketones; Leucine; Lipid Metabolism; Liver; Male; Peripheral Nervous System Diseases; Rats; Sciatic Nerve; Testicular Diseases	1981
Cell body remodeling during dying-back axonopathy: DRG changes during advanced disease. Journal of neuropathology and experimental neurology, 1982, Volume: 41, Issue:4 Topics: Animals; Axons; Endoplasmic Reticulum; Ganglia, Spinal; Golgi Apparatus; Hexanones; Nerve Degeneration; Neurons; Peripheral Nervous System Diseases; Polyribosomes; Rats; Rats, Inbred Strains; Spinal Nerves	1982
[An experimental study on electrophysiological and histopathological changes in 2,5-hexanedione-intoxicated rats]. Sangyo igaku. Japanese journal of industrial health, 1983, Volume: 25, Issue:2 Topics: Animals; Hexanones; Ketones; Male; Neural Conduction; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Sensation; Spinal Nerve Roots; Tibial Nerve	1983
Axonal atrophy is a specific component of 2,5-hexanedione peripheral neuropathy. Toxicology and applied pharmacology, 1995, Volume: 135, Issue:1 Topics: Administration, Oral; Animals; Atrophy; Axons; Behavior, Animal; Body Weight; Drinking; Hexanones; Injections, Intraperitoneal; Male; Myelin Sheath; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tibial Nerve	1995
Neurotoxic effects of 2,5-hexanedione on rapidly growing unmyelinated peripheral nerve axons of a rat fetus: dose-effect relationship. Environmental research, 1993, Volume: 63, Issue:2 Topics: Animals; Axons; Body Weight; Dose-Response Relationship, Drug; Female; Hexanones; Male; Microscopy, Electron; Peripheral Nervous System Diseases; Pregnancy; Rats; Rats, Sprague-Dawley; Sciatic Nerve	1993
Different administration schedules of the same dose of 2,5-hexanedione influence the development of neuropathy and the toxicokinetics. Neurochemical research, 1997, Volume: 22, Issue:1 Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Drug Administration Schedule; Hexanones; Male; Neural Conduction; Neurotoxins; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains	1997
gamma-diketone peripheral neuropathy. I. Quality morphometric analyses of axonal atrophy and swelling. Toxicology and applied pharmacology, 2000, Jun-01, Volume: 165, Issue:2 Topics: Animals; Atrophy; Axons; Body Weight; Cell Size; Electrophysiology; Gait; Hand Strength; Hexanones; Image Processing, Computer-Assisted; Male; Myelin Sheath; Neurotoxins; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Tibial Nerve	2000
gamma-diketone peripheral neuropathy. II. Neurofilament subunit content. Toxicology and applied pharmacology, 2000, Jun-01, Volume: 165, Issue:2 Topics: Animals; Electrophoresis, Polyacrylamide Gel; Hexanones; Immunoblotting; Male; Molecular Weight; Nerve Tissue Proteins; Neurofilament Proteins; Neurotoxins; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tibial Nerve	2000
Gamma-diketone peripheral neuropathy III. Neurofilament gene expression. Neurotoxicology, 2001, Volume: 22, Issue:2 Topics: Animals; Atrophy; Blotting, Northern; Ganglia, Spinal; Hexanones; Male; Nerve Tissue Proteins; Neurofilament Proteins; Neurotoxins; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; RNA	2001
Experimental neuropathy produced by 2,5-hexanedione--a major metabolite of the neurotoxic industrial solvent methyl n-butyl ketone. Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:8 Topics: Animals; Axons; Environmental Exposure; Hexanones; Ketones; Nerve Fibers, Myelinated; Occupational Diseases; Peripheral Nerves; Peripheral Nervous System Diseases; Rats; Solvents	1975
Phenylmethanesulfonyl fluoride elicits and intensifies the clinical expression of neuropathic insults. Archives of toxicology, 1992, Volume: 66, Issue:1 Topics: Aging; Animals; Carboxylic Ester Hydrolases; Chickens; Female; Hexanones; Peripheral Nervous System Diseases; Phenylmethylsulfonyl Fluoride	1992
The retrograde fast component of axonal transport in motor and sensory nerves of the rat during administration of 2,5-hexanedione. Brain research, 1986, Jul-16, Volume: 378, Issue:1 Topics: Animals; Axonal Transport; Evoked Potentials; Hexanones; Ketones; Male; Motor Neurons; Nerve Tissue Proteins; Neurons, Afferent; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains	1986
Toxic neurofilamentous axonopathies and fast anterograde axonal transport. II. The effects of single doses of neurotoxic and non-neurotoxic diketones and beta, beta'-iminodipropionitrile (IDPN) on the rate and capacity of transport. Neurotoxicology, 1989,Spring, Volume: 10, Issue:1 Topics: Animals; Axonal Transport; Axons; Cytoskeleton; Hexanones; Intermediate Filaments; Male; Nerve Tissue Proteins; Nitriles; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains	1989
Giant axonal neuropathy: acceleration of neurofilament transport in optic axons. Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:3 Topics: Animals; Axonal Transport; Axons; Biological Transport; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Hexanones; Male; Molecular Weight; Optic Nerve; Peptides; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains	1985
Effects of vitamin B12 and B6 on 2,5-hexanedione-induced neuropathy. Archives of toxicology, 1985, Volume: 56, Issue:3 Topics: Animals; Hexanones; Ketones; Male; Peripheral Nervous System Diseases; Pyridoxine; Rats; Rats, Inbred Strains; Vitamin B 12	1985
Hexacarbon neuropathy: tracking a toxin. Neurotoxicology, 1985,Winter, Volume: 6, Issue:4 Topics: Animals; Biotransformation; Hexanes; Hexanones; Humans; Intermediate Filament Proteins; Isomerism; Ketones; Methyl n-Butyl Ketone; Neurofilament Proteins; Occupational Diseases; Peripheral Nervous System Diseases; Pyrroles; Rats; Textile Industry	1985
Urinary excretion of 2,5-hexanedione and peripheral polyneuropathies workers exposed to hexane. Journal of toxicology and environmental health, 1987, Volume: 20, Issue:3 Topics: Adolescent; Adult; Electromyography; Female; Hexanes; Hexanones; Humans; Ketones; Male; Middle Aged; Occupational Diseases; Peripheral Nervous System Diseases; Shoes	1987
2,5-Hexanedione neuropathy is associated with the covalent crosslinking of neurofilament proteins. Neurochemical pathology, 1986, Volume: 5, Issue:1 Topics: Animals; Chemical Phenomena; Chemistry; Electrophoresis, Polyacrylamide Gel; Hexanones; Intermediate Filament Proteins; Ketones; Peripheral Nerves; Peripheral Nervous System Diseases; Rats; Rats, Inbred Lew	1986