2,5-hexanedione has been researched along with Encephalopathy, Toxic in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; Gao, B; Jiang, L; Liu, X; Piao, F; Shi, X; Wang, N; Yang, G; Yu, L; Zhang, C | 1 |
| Li, M; Li, X; Liu, Z; Wang, Q; Wang, S; Xie, K; Yu, T | 1 |
| Hou, L; Huang, R; Li, S; Wang, Q; Yang, J; Zhang, D; Zhao, J | 1 |
| Hou, L; Huang, R; Ruan, Z; Sun, W; Wang, Q; Zhang, D | 1 |
| Hou, LY; Wang, QS; Xie, KQ; Yu, SF; Zhang, CL; Zhao, XL | 1 |
| Kayton, R; Lasarev, M; Monterroso, V; Sabri, M; Spencer, P; Tshala-Katumbay, D | 1 |
| DeCaprio, AP; Kinney, EA; LoPachin, RM | 1 |
| He, D; LoPachin, RM; Opanashuk, LA; Reid, ML | 1 |
| Decaprio, AP; Lopachin, RM | 1 |
| Hou, LY; Song, FY; Wang, QS; Xie, KQ; Zhang, CL | 1 |
| Eyer, J; Peterson, AP; Sickles, DW; Stone, JD | 1 |
1 review(s) available for 2,5-hexanedione and Encephalopathy, Toxic
| Article | Year |
|---|---|
Protein adduct formation as a molecular mechanism in neurotoxicity.
Topics: Acrylamide; Animals; Hexanones; Humans; Nerve Tissue Proteins; Neurotoxicity Syndromes; Neurotoxins; Protein Binding; Xenobiotics | 2005 |
10 other study(ies) available for 2,5-hexanedione and Encephalopathy, Toxic
| Article | Year |
|---|---|
2,5-hexanedione-induced deregulation of axon-related microRNA expression in rat nerve tissues.
Topics: Animals; Axons; Brain-Derived Neurotrophic Factor; Databases, Genetic; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Hexanones; Male; MAP Kinase Kinase Kinase 1; MicroRNAs; Microtubule-Associated Proteins; Neurotoxicity Syndromes; Rats, Sprague-Dawley; Sciatic Nerve; Signal Transduction; Solvents; Spinal Cord; Transcriptome | 2020 |
Diallyl sulfide-induced attenuation of n-hexane-induced peripheral nerve impairment is associated with metabolic inhibition of n-hexane.
Topics: Allyl Compounds; Animals; Body Weight; Hair; Hexanes; Hexanones; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Pyrroles; Rats, Wistar; Sciatic Nerve; Sulfides | 2020 |
Glibenclamide attenuates 2,5-hexanedione-induced neurotoxicity in the spinal cord of rats through mitigation of NLRP3 inflammasome activation, neuroinflammation and oxidative stress.
Topics: Animals; Antioxidants; Glyburide; Hexanones; Inflammasomes; Male; Neuroprotective Agents; Neurotoxicity Syndromes; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Rats, Sprague-Dawley; Spinal Cord | 2020 |
NLRP3 inflammasome mediates 2,5-hexanedione-induced neurotoxicity through regulation of macrophage infiltration in rats.
Topics: Animals; Antioxidants; Cell Movement; Glutathione; Glyburide; Hexanones; Inflammasomes; Intracellular Signaling Peptides and Proteins; Macrophages; Male; Neurotoxicity Syndromes; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phosphate-Binding Proteins; Pyroptosis; Rats; Sciatic Nerve | 2020 |
2,5-hexanedione (HD) treatment alters calmodulin, Ca2+/calmodulin-dependent protein kinase II, and protein kinase C in rats' nerve tissues.
Topics: Animals; Body Weight; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Cell Membrane; Cerebral Cortex; Cytosol; Gait; Gait Disorders, Neurologic; Hexanones; Lameness, Animal; Male; Nervous System; Neurofilament Proteins; Neurotoxicity Syndromes; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Time Factors; Up-Regulation | 2008 |
Probing mechanisms of axonopathy. Part II: Protein targets of 2,5-hexanedione, the neurotoxic metabolite of the aliphatic solvent n-hexane.
Topics: Acetophenones; Amino Acids; Animals; Axons; Biomarkers; Cell Shape; Electrophoresis, Polyacrylamide Gel; Hexanes; Hexanones; Isoelectric Focusing; Male; Nerve Tissue Proteins; Neurofilament Proteins; Neurotoxicity Syndromes; Neurotoxins; Proteomics; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spinal Cord | 2009 |
Comparative covalent protein binding of 2,5-hexanedione and 3-acetyl-2,5-hexanedione in the rat.
Topics: Animals; Axons; Cytoskeletal Proteins; Ergosterol; Hexanes; Hexanones; Male; Molecular Structure; Neurotoxicity Syndromes; Rats; Rats, Wistar; Spinal Cord | 2009 |
2,5-Hexanedione-induced changes in the monomeric neurofilament protein content of rat spinal cord fractions.
Topics: Administration, Oral; Animals; Atrophy; Axons; Dose-Response Relationship, Drug; Hexanones; Lumbosacral Region; Male; Nerve Degeneration; Neurofilament Proteins; Neurotoxicity Syndromes; Neurotoxins; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Diseases; Subcellular Fractions | 2004 |
Changes of cytoskeletal proteins in nerve tissues and serum of rats treated with 2,5-hexanedione.
Topics: Actins; Animals; Biomarkers; Blotting, Western; Body Weight; Cerebral Cortex; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Hexanones; Lameness, Animal; Male; Microfilament Proteins; Microtubule Proteins; Nerve Tissue; Neurofilament Proteins; Neurotoxicity Syndromes; Neurotoxins; Polyethylene Glycols; Rats; Rats, Wistar; Sciatic Nerve; Solvents; Substantia Nigra; Tubulin | 2008 |
Neurofilaments are non-essential elements of toxicant-induced reductions in fast axonal transport: pulse labeling in CNS neurons.
Topics: Acrylamide; Animals; Axonal Transport; Central Nervous System; Hexanones; Kinetics; Male; Mice; Mice, Transgenic; Neurofilament Proteins; Neurons; Neurotoxicity Syndromes; Neurotoxins | 2000 |