2,5-hexanedione has been researched along with Atrophy in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 8 (42.11) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Das, S; Jortner, BS; LoPachin, RM; Reid, ML | 1 |
| He, D; LoPachin, RM; Opanashuk, LA; Reid, ML | 1 |
| DeCaprio, AP; LoPachin, RM | 1 |
| Jortner, BS; Lopachin, RM; Monir, A; Reid, ML | 1 |
| Qian, Y; Zeng, F | 1 |
| Baker, TS; Bus, JS; Gillies, PJ; Norton, RM | 1 |
| Bus, JS; Chapin, RE; Morgan, KT | 1 |
| Dyer, KS; Jortner, BS; Lehning, EJ; LoPachin, RM | 1 |
| Allard, EK; Blanchard, KT; Boekelheide, K | 2 |
| Allard, EK; Boekelheide, K | 1 |
| Graham, DG | 1 |
| Gambetti, P; Sayre, LM | 1 |
| Blanchard, KT; Boekelheide, K; Lee, J | 1 |
| Ihata, Y; Iijima, N; Ishihara, A; Miyamoto, E; Nagano, K; Ohira, A; Oishi, Y | 1 |
| Arezzo, JC; Fox, JH; Jortner, BS; Kitano, T; Lehning, EJ; LoPachin, RM | 1 |
| He, DK; Lehning, EJ; LoPachin, RM; Opanashuk, LA | 1 |
| Boekelheide, K | 1 |
| Saxena, AK; Shanker, R; Singh, KP; Upreti, RK | 1 |
1 review(s) available for 2,5-hexanedione and Atrophy
| Article | Year |
|---|---|
gamma-Diketone neuropathy: axon atrophy and the role of cytoskeletal protein adduction.
Topics: Animals; Atrophy; Axons; Cytoskeletal Proteins; Hexanones; Neurofilament Proteins; Neurotoxins; Tibial Nerve | 2004 |
18 other study(ies) available for 2,5-hexanedione and Atrophy
| Article | Year |
|---|---|
gamma-diketone central neuropathy: quantitative morphometric analysis of axons in rat spinal cord white matter regions and nerve roots.
Topics: Animals; Atrophy; Axons; Hexanones; Image Processing, Computer-Assisted; Male; Nerve Degeneration; Nerve Tissue; Neurotoxins; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord Diseases; Statistics, Nonparametric | 2003 |
2,5-Hexanedione-induced changes in the monomeric neurofilament protein content of rat spinal cord fractions.
Topics: Administration, Oral; Animals; Atrophy; Axons; Dose-Response Relationship, Drug; Hexanones; Lumbosacral Region; Male; Nerve Degeneration; Neurofilament Proteins; Neurotoxicity Syndromes; Neurotoxins; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Diseases; Subcellular Fractions | 2004 |
Gamma-Diketone central neuropathy: quantitative analyses of cytoskeletal components in myelinated axons of the rat rubrospinal tract.
Topics: Animals; Atrophy; Axons; Body Weight; Cytoskeleton; Dose-Response Relationship, Drug; Hexanones; Male; Microfilament Proteins; Microtubules; Neurotoxins; Rats; Rats, Sprague-Dawley; Spinal Cord; Statistics, Nonparametric | 2005 |
Re-establishment of spermatogenesis by diethylstilbestrol after 2,5-hexanedione-induced irreversible testicular atrophy in rats.
Topics: Animals; Antineoplastic Agents, Hormonal; Atrophy; Body Weight; Diethylstilbestrol; Hexanones; Hormones; Male; Organ Size; Rats; Rats, Sprague-Dawley; Spermatogenesis; Testis; Testosterone | 2008 |
Altered lipid metabolism in 2,5-hexanedione-induced testicular atrophy and peripheral neuropathy in the rat.
Topics: Acetates; Animals; Atrophy; Hexanones; Ketones; Leucine; Lipid Metabolism; Liver; Male; Peripheral Nervous System Diseases; Rats; Sciatic Nerve; Testicular Diseases | 1981 |
The morphogenesis of testicular degeneration induced in rats by orally administered 2,5-hexanedione.
Topics: Animals; Atrophy; Cell Nucleus; Endoplasmic Reticulum; Golgi Apparatus; Hexanones; Ketones; Male; Rats; Rats, Inbred F344; Seminiferous Epithelium; Spermatids; Spermatogenesis; Testis; Time Factors | 1983 |
Axonal atrophy is a specific component of 2,5-hexanedione peripheral neuropathy.
Topics: Administration, Oral; Animals; Atrophy; Axons; Behavior, Animal; Body Weight; Drinking; Hexanones; Injections, Intraperitoneal; Male; Myelin Sheath; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tibial Nerve | 1995 |
Fate of germ cells in 2,5-hexanedione-induced testicular injury. I. Apoptosis is the mechanism of germ cell death.
Topics: Animals; Apoptosis; Atrophy; Cell Death; Digoxigenin; DNA; DNA Nucleotidylexotransferase; Electrophoresis, Agar Gel; Hexanones; Male; Rats; Rats, Inbred F344; Spermatozoa; Staining and Labeling; Testis; Uridine Triphosphate | 1996 |
Exogenous stem cell factor (SCF) compensates for altered endogenous SCF expression in 2,5-hexanedione-induced testicular atrophy in rats.
Topics: Animals; Apoptosis; Atrophy; Base Sequence; Cell Division; Coculture Techniques; Dose-Response Relationship, Drug; Hexanones; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spermatozoa; Stem Cell Factor; Testicular Diseases; Testis | 1996 |
Fate of germ cells in 2,5-hexanedione-induced testicular injury. II. Atrophy persists due to a reduced stem cell mass and ongoing apoptosis.
Topics: Animals; Apoptosis; Atrophy; Cholinesterase Inhibitors; DNA; Hexanones; Male; Rats; Rats, Sprague-Dawley; Spermatogonia; Staining and Labeling; Stem Cells; Testis | 1996 |
Protein crosslinking correlates with axonal atrophy, swelling and degeneration in gamma-diketone neuropathy: commentary on forum position paper.
Topics: Animals; Atrophy; Axons; Cross-Linking Reagents; Hexanones; Humans; Ketones; Nerve Degeneration; Nerve Tissue Proteins; Neurotoxins; Structure-Activity Relationship | 1997 |
Mechanistic importance of axonal atrophy and swelling in gamma-diketone axonopathy: commentary on forum position paper.
Topics: Animals; Atrophy; Axons; Hexanones; Humans; Ketones; Neurotoxins | 1997 |
Leuprolide, a gonadotropin-releasing hormone agonist, reestablishes spermatogenesis after 2,5-hexanedione-induced irreversible testicular injury in the rat, resulting in normalized stem cell factor expression.
Topics: Animals; Atrophy; Hexanones; Leuprolide; Male; Rats; Rats, Inbred F344; Spermatogenesis; Stem Cell Factor; Testis | 1998 |
[Effect of 2,5-hexanedione on myosin heavy chain isoform content in perineal muscles of the rats].
Topics: Animals; Atrophy; Hexanones; Male; Muscle Fibers, Fast-Twitch; Muscle, Skeletal; Myosin Heavy Chains; Neurotoxins; Perineum; Protein Isoforms; Rats; Rats, Wistar; Succinate Dehydrogenase | 1999 |
gamma-diketone peripheral neuropathy. I. Quality morphometric analyses of axonal atrophy and swelling.
Topics: Animals; Atrophy; Axons; Body Weight; Cell Size; Electrophysiology; Gait; Hand Strength; Hexanones; Image Processing, Computer-Assisted; Male; Myelin Sheath; Neurotoxins; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Tibial Nerve | 2000 |
Gamma-diketone peripheral neuropathy III. Neurofilament gene expression.
Topics: Animals; Atrophy; Blotting, Northern; Ganglia, Spinal; Hexanones; Male; Nerve Tissue Proteins; Neurofilament Proteins; Neurotoxins; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; RNA | 2001 |
2,5-Hexanedione alters microtubule assembly. I. Testicular atrophy, not nervous system toxicity, correlates with enhanced tubulin polymerization.
Topics: Animals; Atrophy; Brain; Hexanones; Ketones; Male; Microtubules; Polymers; Rats; Testis; Tubulin | 1987 |
Comparative study of 2,5-hexanediol and 2,5-hexanedione induced thymic toxicity in weanling and adult rats.
Topics: Aging; Animals; Atrophy; Glycols; Hexanones; Ketones; Male; Organ Size; Organ Specificity; Rats; Thymus Gland | 1986 |