Compounds > 2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone
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2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone and Colonic Neoplasms

2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone has been researched along with Colonic Neoplasms in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de la Cruz, A; Gibson, NW; Phillips, RM; Traver, RD1
Gibson, NW; Lee, CS; Pfeifer, GP1
Ross, D; Sun, X1
Butler, J; Hargreaves, RH; Ross, D; Winski, SL1
Butler, J; Gibson, NW; Hartley, JA; Ross, D; Siegel, D1

Other Studies

5 other study(ies) available for 2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone and Colonic Neoplasms

ArticleYear
Increased activity and expression of NAD(P)H:quinone acceptor oxidoreductase in confluent cell cultures and within multicellular spheroids.
    Cancer research, 1994, Jul-15, Volume: 54, Issue:14

    Topics: Aziridines; Base Sequence; Benzoquinones; Cell Division; Colonic Neoplasms; Gene Expression; Humans; Molecular Sequence Data; Quinone Reductases; Tumor Cells, Cultured

1994
Mapping of DNA alkylation sites induced by aziridinylbenzoquinones in human cells by ligation-mediated polymerase chain reaction.
    Cancer research, 1994, Apr-01, Volume: 54, Issue:7

    Topics: Alkylation; Antineoplastic Agents; Aziridines; Base Sequence; Benzoquinones; Binding Sites; Cell Line; Colonic Neoplasms; DNA; DNA Primers; DNA, Neoplasm; Exons; Genes, p53; Humans; Molecular Sequence Data; NAD(P)H Dehydrogenase (Quinone); Phosphoglycerate Kinase; Polymerase Chain Reaction; Tumor Cells, Cultured

1994
Quinone-induced apoptosis in human colon adenocarcinoma cells via DT-diaphorase mediated bioactivation.
    Chemico-biological interactions, 1996, May-06, Volume: 100, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Aziridines; Benzoquinones; Colonic Neoplasms; Electrophoresis, Agar Gel; Humans; Mitomycin; NAD(P)H Dehydrogenase (Quinone); NADH, NADPH Oxidoreductases; Streptonigrin; Tumor Cells, Cultured

1996
A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:12

    Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Biotransformation; Cell Division; Colonic Neoplasms; Drug Screening Assays, Antitumor; Gene Targeting; Humans; Hydroquinones; NAD(P)H Dehydrogenase (Quinone); Transfection; Tumor Cells, Cultured

1998
Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity.
    Molecular pharmacology, 1992, Volume: 42, Issue:3

    Topics: Animals; Antineoplastic Agents; Aziridines; Benzoquinones; Colonic Neoplasms; DNA Damage; Humans; Liver; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Rats; Tumor Cells, Cultured

1992