2,5-dihydroxybenzoic acid has been researched along with Reperfusion Injury in 14 studies
2,5-dihydroxybenzoic acid: RN given refers to parent cpd; a oxidative product of saligenin
2,5-dihydroxybenzoic acid : A dihydroxybenzoic acid having the two hydroxy groups at the 2- and 5-positions.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preexisting hyperglycemia is associated with enhanced reperfusion injury in the postischemic rat brain." | 1.30 | Hydroxyl radical formation in hyperglycemic rats during middle cerebral artery occlusion/reperfusion. ( Huang, NC; Quast, MJ; Wei, J, 1997) |
| "Preischemic hyperglycemia is known to aggravate brain damage resulting from transient ischemia." | 1.30 | Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia. ( Floyd, RA; He, QP; Li, PA; Liu, GJ; Siesjö, BK, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (78.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, E | 1 |
| Ramos, SV | 1 |
| Huang, X | 1 |
| Liu, Y | 1 |
| Botta, A | 1 |
| Sung, HK | 1 |
| Turnbull, PC | 1 |
| Wheeler, MB | 1 |
| Berger, T | 1 |
| Wilson, DJ | 1 |
| Perry, CGR | 1 |
| Mak, TW | 1 |
| Sweeney, G | 1 |
| Arab, HA | 1 |
| Walker, NI | 1 |
| Cheung, K | 1 |
| Hickman, PE | 1 |
| Potter, JM | 1 |
| Kadkhodaee, M | 1 |
| Roberts, MS | 1 |
| Yang, ZJ | 1 |
| Xie, Y | 1 |
| Bosco, GM | 1 |
| Chen, C | 1 |
| Camporesi, EM | 1 |
| Delbarre, B | 2 |
| Delbarre, G | 2 |
| Calinon, F | 2 |
| Ophir, A | 1 |
| Berenshtein, E | 1 |
| Kitrossky, N | 3 |
| Berman, ER | 1 |
| Photiou, S | 1 |
| Rothman, Z | 1 |
| Chevion, M | 3 |
| Hu, D | 1 |
| Feng, YP | 1 |
| Lancelot, E | 1 |
| Callebert, J | 1 |
| Revaud, ML | 1 |
| Boulu, RG | 1 |
| Plotkine, M | 1 |
| Obata, T | 1 |
| Wei, J | 1 |
| Huang, NC | 1 |
| Quast, MJ | 1 |
| Li, PA | 1 |
| Liu, GJ | 1 |
| He, QP | 1 |
| Floyd, RA | 2 |
| Siesjö, BK | 1 |
| Zager, RA | 1 |
| Gmur, DJ | 1 |
| Schimpf, BA | 1 |
| Bredl, CR | 1 |
| Foerder, CA | 1 |
| Udassin, R | 2 |
| Ariel, I | 1 |
| Haskel, Y | 2 |
| Arieli, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Enriched Oxygen Mixtures and Exercise on Oxidative Stress and Stem Cells Proliferation in Athletes.[NCT04366427] | Phase 2 | 42 participants (Actual) | Interventional | 2020-09-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 other studies available for 2,5-dihydroxybenzoic acid and Reperfusion Injury
| Article | Year |
|---|---|
Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes.
Topics: Animals; Gentisates; Hydroxybenzoates; Iron; Lipocalin-2; Male; Mice; Mice, Knockout; Mitochondria; | 2018 |
Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury.
Topics: Acetylcysteine; Animals; Aspartate Aminotransferases; Chromans; Disease Models, Animal; Female; Free | 2015 |
Hyperbaric oxygenation alleviates MCAO-induced brain injury and reduces hydroxyl radical formation and glutamate release.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Gentisates; Glutamates; Hydroxybenzoates; Hydroxyl R | 2010 |
Action of trimetazidine on retina of gerbils after ischemia reperfusion insult: determination of .OH, amino acids, and electroretinogram.
Topics: Amino Acids; Animals; Aspartic Acid; Electroretinography; Female; gamma-Aminobutyric Acid; Gentisate | 1994 |
Hydroxyl radical generation in the cat retina during reperfusion following ischemia.
Topics: Animals; Cats; Eye Proteins; Free Radicals; Gentisates; Hydroxybenzoates; Reactive Oxygen Species; R | 1993 |
[HPLC--detection of hydroxyl radicals in striatum extracellular fluid in rats subjected to reperfusion after cerebral ischemia and the action of vitamin E].
Topics: Animals; Brain Ischemia; Chromatography, High Pressure Liquid; Corpus Striatum; Extracellular Space; | 1993 |
Detection of hydroxyl radicals in rat striatum during transient focal cerebral ischemia: possible implication in tissue damage.
Topics: Analysis of Variance; Animals; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; Gentisa | 1995 |
Use of microdialysis for in-vivo monitoring of hydroxyl free-radical generation in the rat.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Electric Stimulation; Gentisates; Hydrogen Per | 1997 |
Hydroxyl radical formation in hyperglycemic rats during middle cerebral artery occlusion/reperfusion.
Topics: Animals; Arterial Occlusive Diseases; Cerebral Arteries; Cerebral Infarction; Enzyme Inhibitors; Gen | 1997 |
Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia.
Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hype | 1999 |
Evidence against increased hydroxyl radical production during oxygen deprivation-reoxygenation proximal tubular injury.
Topics: Acute Kidney Injury; Animals; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl Radi | 1992 |
Glutamate accumulation and increased hydroxyl free radical formation in the abdominal aorta and heart of gerbil after ischemia/reperfusion insult.
Topics: Animals; Aorta, Abdominal; Female; Free Radicals; Gentisates; Gerbillinae; Glutamates; Glutamic Acid | 1992 |
Salicylate as an in vivo free radical trap: studies on ischemic insult to the rat intestine.
Topics: Animals; Disease Models, Animal; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl R | 1991 |
Direct evidence for the involvement of free radicals in ischemic insult to the intestine.
Topics: Animals; Disease Models, Animal; Free Radicals; Gentisates; Hydroxybenzoates; Intestines; Male; Rats | 1991 |