2,5-dihydroxybenzoic acid has been researched along with Disease Models, Animal in 11 studies
2,5-dihydroxybenzoic acid: RN given refers to parent cpd; a oxidative product of saligenin
2,5-dihydroxybenzoic acid : A dihydroxybenzoic acid having the two hydroxy groups at the 2- and 5-positions.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After a single injection of PTZ at a dose evoking clonic-tonic seizures, PBN did not modify either the formation of free hydroxyl radicals measured by the levels of 2,3-dihydroxybenzoic acid (DHBA) and 2,5-DHBA or the susceptibility to PTZ." | 3.72 | The role of superoxide dismutase and alpha-tocopherol in the development of seizures and kindling induced by pentylenetetrazol - influence of the radical scavenger alpha-phenyl-N-tert-butyl nitrone. ( Keilhoff, G; Krug, M; Rauca, C; Wiswedel, I; Zerbe, R, 2004) |
| "Heart failure was induced in mice via chronic TAC." | 1.51 | Gentisic acid prevents the transition from pressure overload-induced cardiac hypertrophy to heart failure. ( Choi, SY; Jeong, MH; Kee, HJ; Kee, SJ; Kim, GR; Kim, HS; Ryu, Y; Sun, S, 2019) |
| "Osteoporosis is a disease characterized by low bone mass, most commonly caused by an increase in bone resorption that is not matched by sufficient bone formation." | 1.48 | Locally delivered ethyl-2,5-dihydroxybenzoate using 3D printed bone implant for promotion of bone regeneration in a osteoporotic animal model. ( Han, JJ; Kim, D; Kim, J; Kim, MS; Koo, MA; Kwon, BJ; Lee, MH; Park, JC; Seon, GM, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kwon, BJ | 1 |
| Seon, GM | 1 |
| Lee, MH | 1 |
| Koo, MA | 1 |
| Kim, MS | 1 |
| Kim, D | 2 |
| Han, JJ | 1 |
| Kim, J | 1 |
| Park, JC | 1 |
| Sun, S | 1 |
| Kee, HJ | 1 |
| Ryu, Y | 1 |
| Choi, SY | 1 |
| Kim, GR | 1 |
| Kim, HS | 1 |
| Kee, SJ | 1 |
| Jeong, MH | 1 |
| Arab, HA | 1 |
| Walker, NI | 1 |
| Cheung, K | 1 |
| Hickman, PE | 1 |
| Potter, JM | 1 |
| Kadkhodaee, M | 1 |
| Roberts, MS | 1 |
| Kwon, TH | 1 |
| Chao, DL | 1 |
| Malloy, K | 1 |
| Sun, D | 1 |
| Alessandri, B | 1 |
| Bullock, MR | 1 |
| Rauca, C | 1 |
| Wiswedel, I | 1 |
| Zerbe, R | 1 |
| Keilhoff, G | 1 |
| Krug, M | 1 |
| Dahchour, A | 1 |
| Lallemand, F | 1 |
| Ward, RJ | 1 |
| De Witte, P | 1 |
| Cai, Q | 1 |
| Takemura, G | 1 |
| Ashraf, M | 1 |
| Lancelot, E | 1 |
| Callebert, J | 1 |
| Revaud, ML | 1 |
| Boulu, RG | 1 |
| Plotkine, M | 1 |
| Andreassen, OA | 1 |
| Ferrante, RJ | 1 |
| Dedeoglu, A | 1 |
| Albers, DW | 1 |
| Klivenyi, P | 1 |
| Carlson, EJ | 1 |
| Epstein, CJ | 1 |
| Beal, MF | 1 |
| Udassin, R | 2 |
| Ariel, I | 1 |
| Haskel, Y | 2 |
| Kitrossky, N | 2 |
| Chevion, M | 2 |
| Arieli, I | 1 |
11 other studies available for 2,5-dihydroxybenzoic acid and Disease Models, Animal
| Article | Year |
|---|---|
Locally delivered ethyl-2,5-dihydroxybenzoate using 3D printed bone implant for promotion of bone regeneration in a osteoporotic animal model.
Topics: Animals; Bone and Bones; Bone Density; Bone Regeneration; Cell Differentiation; Coated Materials, Bi | 2018 |
Gentisic acid prevents the transition from pressure overload-induced cardiac hypertrophy to heart failure.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Gentisates; Heart Failure; Male; Mice; Myoc | 2019 |
Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury.
Topics: Acetylcysteine; Animals; Aspartate Aminotransferases; Chromans; Disease Models, Animal; Female; Free | 2015 |
Tempol, a novel stable nitroxide, reduces brain damage and free radical production, after acute subdural hematoma in the rat.
Topics: Animals; Antioxidants; Brain Chemistry; Brain Damage, Chronic; Cyclic N-Oxides; Disease Models, Anim | 2003 |
The role of superoxide dismutase and alpha-tocopherol in the development of seizures and kindling induced by pentylenetetrazol - influence of the radical scavenger alpha-phenyl-N-tert-butyl nitrone.
Topics: alpha-Tocopherol; Analysis of Variance; Animals; Blotting, Western; Chromatography, High Pressure Li | 2004 |
Production of reactive oxygen species following acute ethanol or acetaldehyde and its reduction by acamprosate in chronically alcoholized rats.
Topics: Acamprosate; Acetaldehyde; Alcohol Deterrents; Alcoholism; Animals; Disease Models, Animal; Ethanol; | 2005 |
Antioxidative properties of histidine and its effect on myocardial injury during ischemia/reperfusion in isolated rat heart.
Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Chromatography, High Pressure Liquid; Disease Models | 1995 |
Detection of hydroxyl radicals in rat striatum during transient focal cerebral ischemia: possible implication in tissue damage.
Topics: Analysis of Variance; Animals; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; Gentisa | 1995 |
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Carrier Prote | 2001 |
Salicylate as an in vivo free radical trap: studies on ischemic insult to the rat intestine.
Topics: Animals; Disease Models, Animal; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl R | 1991 |
Direct evidence for the involvement of free radicals in ischemic insult to the intestine.
Topics: Animals; Disease Models, Animal; Free Radicals; Gentisates; Hydroxybenzoates; Intestines; Male; Rats | 1991 |