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2,5-dihydroxybenzoic acid and Brain Ischemia

2,5-dihydroxybenzoic acid has been researched along with Brain Ischemia in 5 studies

2,5-dihydroxybenzoic acid: RN given refers to parent cpd; a oxidative product of saligenin
2,5-dihydroxybenzoic acid : A dihydroxybenzoic acid having the two hydroxy groups at the 2- and 5-positions.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Preischemic hyperglycemia is known to aggravate brain damage resulting from transient ischemia."1.30Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia. ( Floyd, RA; He, QP; Li, PA; Liu, GJ; Siesjö, BK, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hu, D1
Feng, YP1
Althaus, JS2
Andrus, PK2
Williams, CM1
VonVoigtlander, PF2
Cazers, AR1
Hall, ED2
Christensen, T1
Bruhn, T1
Balchen, T1
Diemer, NH1
Li, PA1
Liu, GJ1
He, QP1
Floyd, RA1
Siesjö, BK1

Other Studies

5 other studies available for 2,5-dihydroxybenzoic acid and Brain Ischemia

ArticleYear
[HPLC--detection of hydroxyl radicals in striatum extracellular fluid in rats subjected to reperfusion after cerebral ischemia and the action of vitamin E].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:5

    Topics: Animals; Brain Ischemia; Chromatography, High Pressure Liquid; Corpus Striatum; Extracellular Space;

1993
The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury. Reversal by tirilazad mesylate (U-74006F).
    Molecular and chemical neuropathology, 1993, Volume: 20, Issue:2

    Topics: Animals; Brain Injuries; Brain Ischemia; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydr

1993
Hydroxyl radical production and lipid peroxidation parallels selective post-ischemic vulnerability in gerbil brain.
    Journal of neuroscience research, 1993, Volume: 34, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Cerebral Cortex; Cytochrome P-450 Enzyme Inhibitors; Dose-Response R

1993
Evidence for formation of hydroxyl radicals during reperfusion after global cerebral ischaemia in rats using salicylate trapping and microdialysis.
    Neurobiology of disease, 1994, Volume: 1, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Male;

1994
Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia.
    Free radical biology & medicine, 1999, Volume: 27, Issue:9-10

    Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hype

1999