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2,5-dihydroxybenzoic acid and Alkaptonuria

2,5-dihydroxybenzoic acid has been researched along with Alkaptonuria in 1 studies

2,5-dihydroxybenzoic acid: RN given refers to parent cpd; a oxidative product of saligenin
2,5-dihydroxybenzoic acid : A dihydroxybenzoic acid having the two hydroxy groups at the 2- and 5-positions.

Alkaptonuria: An inborn error of amino acid metabolism resulting from a defect in the enzyme HOMOGENTISATE 1,2-DIOXYGENASE, an enzyme involved in the breakdown of PHENYLALANINE and TYROSINE. It is characterized by accumulation of HOMOGENTISIC ACID in the urine, OCHRONOSIS in various tissues, and ARTHRITIS.

Research Excerpts

ExcerptRelevanceReference
"Gentisic acid (GA), a metabolite of acetylsalicylic acid (ASA), and homogentisic acid (HGA), which is excreted at high levels in alkaptonuria, are divalent phenolic acids with very similar structures."3.96Novel absorbance peak of gentisic acid following the oxidation reaction. ( Ejima, Y; Hirakawa, E; Hosokawa, S; Morinishi, T; Ohsaki, H; Shimosawa, T; Shukuya, K; Sogabe, K; Tokuhara, Y, 2020)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Hosokawa, S1
Shukuya, K1
Sogabe, K1
Ejima, Y1
Morinishi, T1
Hirakawa, E1
Ohsaki, H1
Shimosawa, T1
Tokuhara, Y1

Other Studies

1 other study available for 2,5-dihydroxybenzoic acid and Alkaptonuria

ArticleYear
Novel absorbance peak of gentisic acid following the oxidation reaction.
    PloS one, 2020, Volume: 15, Issue:4

    Topics: Alkaptonuria; Aspirin; Chromatography, Liquid; Gentisates; Homogentisic Acid; Humans; Mass Spectrome

2020