Page last updated: 2024-10-27

2,5-dihydroxybenzoic acid and Acute Brain Injuries

2,5-dihydroxybenzoic acid has been researched along with Acute Brain Injuries in 4 studies

2,5-dihydroxybenzoic acid: RN given refers to parent cpd; a oxidative product of saligenin
2,5-dihydroxybenzoic acid : A dihydroxybenzoic acid having the two hydroxy groups at the 2- and 5-positions.

Research Excerpts

ExcerptRelevanceReference
"Preischemic hyperglycemia is known to aggravate brain damage resulting from transient ischemia."1.30Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia. ( Floyd, RA; He, QP; Li, PA; Liu, GJ; Siesjö, BK, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, ZJ1
Xie, Y1
Bosco, GM1
Chen, C1
Camporesi, EM1
Globus, MY1
Alonso, O1
Dietrich, WD1
Busto, R1
Ginsberg, MD1
Althaus, JS1
Andrus, PK1
Williams, CM1
VonVoigtlander, PF1
Cazers, AR1
Hall, ED1
Li, PA1
Liu, GJ1
He, QP1
Floyd, RA1
Siesjö, BK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Enriched Oxygen Mixtures and Exercise on Oxidative Stress and Stem Cells Proliferation in Athletes.[NCT04366427]Phase 242 participants (Actual)Interventional2020-09-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for 2,5-dihydroxybenzoic acid and Acute Brain Injuries

ArticleYear
Hyperbaric oxygenation alleviates MCAO-induced brain injury and reduces hydroxyl radical formation and glutamate release.
    European journal of applied physiology, 2010, Volume: 108, Issue:3

    Topics: Animals; Blood Pressure; Brain; Brain Injuries; Gentisates; Glutamates; Hydroxybenzoates; Hydroxyl R

2010
Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia.
    Journal of neurochemistry, 1995, Volume: 65, Issue:4

    Topics: Animals; Brain Injuries; Free Radicals; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radica

1995
The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury. Reversal by tirilazad mesylate (U-74006F).
    Molecular and chemical neuropathology, 1993, Volume: 20, Issue:2

    Topics: Animals; Brain Injuries; Brain Ischemia; Free Radical Scavengers; Gentisates; Hydroxybenzoates; Hydr

1993
Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia.
    Free radical biology & medicine, 1999, Volume: 27, Issue:9-10

    Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hype

1999