Page last updated: 2024-11-05

2,4-thiazolidinedione and Weight Loss

2,4-thiazolidinedione has been researched along with Weight Loss in 6 studies

thiazolidine-2,4-dione: structure in first source
1,3-thiazolidine-2,4-dione : A thiazolidenedione carrying oxo substituents at positions 2 and 4.

Weight Loss: Decrease in existing BODY WEIGHT.

Research Excerpts

ExcerptRelevanceReference
"Weight loss is the best treatment option, which can be a challenging task for patients to achieve and maintain."2.46Managing highly insulin-resistant diabetes mellitus: weight loss approaches and medical management. ( Brown, A; Desai, M; Taneja, D; Tannock, LR, 2010)
"Type 2 diabetes mellitus is a major cause of morbidity and mortality worldwide, and the prevalence is set to increase dramatically over the coming decades."2.43Etiology of insulin resistance. ( Petersen, KF; Shulman, GI, 2006)
"For now, the goals and methods of treating hypertension and dyslipidemia are the same in people with the metabolic syndrome as in the general population."2.41A truly deadly quartet: obesity, hypertension, hypertriglyceridemia, and hyperinsulinemia. ( Hoogwerf, BJ; Nambi, V; Sprecher, DL, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, A1
Desai, M1
Taneja, D1
Tannock, LR1
Nambi, V1
Hoogwerf, BJ2
Sprecher, DL1
Petersen, KF1
Shulman, GI1
Zinman, B1
Durán García, S1
Milton, DR1
Giaconia, JM1
Kim, DD1
Trautmann, ME1
Brodows, RG1
Castro Cabezas, M1
Halkes, CJ1
Erkelens, DW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Thiazolidinediones or Thiazolidinediones and Metformin[NCT00099320]Phase 3182 participants (Actual)Interventional2004-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for 2,4-thiazolidinedione and Weight Loss

ArticleYear
Managing highly insulin-resistant diabetes mellitus: weight loss approaches and medical management.
    Postgraduate medicine, 2010, Volume: 122, Issue:1

    Topics: Amyloid; Bariatric Surgery; Diabetes Mellitus; Diet, Reducing; Dipeptidyl-Peptidase IV Inhibitors; E

2010
A truly deadly quartet: obesity, hypertension, hypertriglyceridemia, and hyperinsulinemia.
    Cleveland Clinic journal of medicine, 2002, Volume: 69, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Hyperinsulinism; Hypertension; Hypertrigly

2002
Etiology of insulin resistance.
    The American journal of medicine, 2006, Volume: 119, Issue:5 Suppl 1

    Topics: Diabetes Mellitus, Type 2; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Insulin Receptor

2006
Obesity and free fatty acids: double trouble.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2001, Volume: 11, Issue:2

    Topics: Chylomicrons; Coronary Artery Disease; Fatty Acids, Nonesterified; Humans; Hyperglycemia; Hyperlipid

2001

Trials

1 trial available for 2,4-thiazolidinedione and Weight Loss

ArticleYear
The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes: a randomized trial.
    Annals of internal medicine, 2007, Apr-03, Volume: 146, Issue:7

    Topics: Adult; Aged; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 2; Double-Blind M

2007

Other Studies

1 other study available for 2,4-thiazolidinedione and Weight Loss

ArticleYear
Summaries for patients. Exenatide therapy for type 2 diabetes.
    Annals of internal medicine, 2007, Apr-03, Volume: 146, Issue:7

    Topics: Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Exenatide; F

2007