2,4-thiazolidinedione has been researched along with Parkinson Disease in 3 studies
thiazolidine-2,4-dione: structure in first source
1,3-thiazolidine-2,4-dione : A thiazolidenedione carrying oxo substituents at positions 2 and 4.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, HL | 1 |
| Lin, HC | 1 |
| Tseng, YF | 1 |
| Chao, JC | 1 |
| Hsu, CY | 1 |
| Connolly, JG | 1 |
| Bykov, K | 1 |
| Gagne, JJ | 1 |
| Carta, AR | 1 |
| Pisanu, A | 1 |
1 review available for 2,4-thiazolidinedione and Parkinson Disease
| Article | Year |
|---|---|
Modulating microglia activity with PPAR-γ agonists: a promising therapy for Parkinson's disease?
Topics: Animals; Antiparkinson Agents; Encephalitis; Humans; Microglia; Parkinson Disease; Pioglitazone; PPA | 2013 |
2 other studies available for 2,4-thiazolidinedione and Parkinson Disease
| Article | Year |
|---|---|
Association of thiazolidinedione with a lower risk of Parkinson's disease in a population with newly-diagnosed diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Diabetes Mellitus; Dose-Response Relationship, | 2018 |
Thiazolidinediones and Parkinson Disease: A Cohort Study.
Topics: Aged; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Male; Parkinso | 2015 |