2,4-thiazolidinedione has been researched along with Pancreatic Neoplasms in 5 studies
thiazolidine-2,4-dione: structure in first source
1,3-thiazolidine-2,4-dione : A thiazolidenedione carrying oxo substituents at positions 2 and 4.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "AsPC-1 human pancreatic cancer cells, transfected with a PPRE-luciferase construct, demonstrated increased luminescence following treatment with PPARgamma ligands, indicating the presence of functional PPARgamma protein." | 1.32 | Activation of PPARgamma increases PTEN expression in pancreatic cancer cells. ( Evers, BM; Farrow, B, 2003) |
| "PPARgamma was expressed in five human pancreatic cancer cell lines: Capan-1, AsPC-1, BxPC-3, PANC-1, and MIA PaCa-2." | 1.31 | PPARgamma ligand (thiazolidinedione) induces growth arrest and differentiation markers of human pancreatic cancer cells. ( Elnemr, A; Fushida, S; Iwata, K; Kayahara, M; Kitagawa, H; Miwa, K; Ninomia, I; Nishimura, G; Ohta, T; Terada, T; Yamamoto, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Engel, BJ | 1 |
| Carson, DD | 1 |
| Farrow, B | 1 |
| Evers, BM | 1 |
| Elnemr, A | 2 |
| Ohta, T | 2 |
| Iwata, K | 1 |
| Ninomia, I | 1 |
| Fushida, S | 2 |
| Nishimura, G | 2 |
| Kitagawa, H | 2 |
| Kayahara, M | 2 |
| Yamamoto, M | 2 |
| Terada, T | 1 |
| Miwa, K | 2 |
| Ninomiya, I | 1 |
| Fujimura, T | 1 |
| Shimizu, K | 1 |
| Yi, S | 1 |
| Yeh, TK | 1 |
| Kuo, CC | 1 |
| Lee, YZ | 1 |
| Ke, YY | 1 |
| Chu, KF | 1 |
| Hsu, HY | 1 |
| Chang, HY | 1 |
| Liu, YW | 1 |
| Song, JS | 1 |
| Yang, CW | 1 |
| Lin, LM | 1 |
| Sun, M | 1 |
| Wu, SH | 1 |
| Kuo, PC | 1 |
| Shih, C | 1 |
| Chen, CT | 1 |
| Tsou, LK | 1 |
| Lee, SJ | 1 |
5 other studies available for 2,4-thiazolidinedione and Pancreatic Neoplasms
| Article | Year |
|---|---|
Activated EGFR stimulates MUC1 expression in human uterine and pancreatic cancer cell lines.
Topics: Blotting, Western; Cell Line, Tumor; Epidermal Growth Factor; ErbB Receptors; Female; Gene Expressio | 2013 |
Activation of PPARgamma increases PTEN expression in pancreatic cancer cells.
Topics: DNA-Binding Proteins; Genes, Reporter; Humans; Ligands; Nuclear Proteins; Pancreatic Neoplasms; Phos | 2003 |
PPARgamma ligand (thiazolidinedione) induces growth arrest and differentiation markers of human pancreatic cancer cells.
Topics: Adenocarcinoma; Antigens, Differentiation; Antigens, Neoplasm; Antineoplastic Agents; Blotting, West | 2000 |
Thiazolidinedione, a peroxisome proliferator-activated receptor-gamma ligand, modulates the E-cadherin/beta-catenin system in a human pancreatic cancer cell line, BxPC-3.
Topics: beta Catenin; Blotting, Western; Cadherins; Carcinoembryonic Antigen; Cell Differentiation; Cytoskel | 2002 |
Design, Synthesis, and Evaluation of Thiazolidine-2,4-dione Derivatives as a Novel Class of Glutaminase Inhibitors.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Enzyme Inhibitors | 2017 |